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Full record GDS3799

Bone morphogenetic protein type II receptor mutation effect on lung

Analysis of lung from transgenics expressing a BMPR2 tail domain mutation (BMPR2R899X) in smooth muscle. Nine weeks of BMPR2R899X expression can result in elevated right ventricular systolic pressures (RVSP), producing a mutant phenotype relevant to human pulmonary arterial hypertension (PAH).
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL1261
Series:
GSE11018
6 Samples
Download data: CEL, CHP

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