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Full record GDS4018

Anti-CD3 monoclonal antibody effect on splenic Foxp3+ regulatory T cells

Analysis of sorted spleen T cells of BDC2.5 RAGo/o Foxp3 NOD mice after anti-CD3 treatment. Anti-CD3 treatment prevented diabetes development in BDC2.5.RAGo/o mice. Results provide insight into the mechanism of action of anti-CD3.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE22527
6 Samples
Download data: CEL

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