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Full record GDS4125

Pten-null, K-ras-activated prostate cancer model

Analysis of prostate tumors from mutants with prostate-specific Pten loss and K-ras activation. In murine models, PTEN deletion alone fails to mimic end stage of human prostate cancer (PC). Results provide insight into cooperation between PTEN loss and RAS activation to promote EMT and metastasis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE34839
6 Samples
Download data: CEL

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