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Full record GDS3371

Laminin alpha2 chain deficiency effect on skeletal muscle

Analysis of hind limb skeletal muscle from 4-week old dy3K/dy3K animals, which completely lack expression of laminin α2 chain. Mutations in the laminin alpha2 chain gene cause congenital muscular dystrophy type 1A (MDC1A). Results provide insight into molecular mechanisms underlying this disorder.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE12049
6 Samples
Download data: CEL

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