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Full record GDS4208

Truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1 effect on spleen cells

Analysis of spleen cells from animals expressing a truncated form of CBF beta-SMMHC lacking the RUNX1 high-affinity binding domain (HABD). The type I CBF beta-SMMHC fusion in acute myeloid leukemia (AML) patients lacks HABD. Results provide insight into the molecular pathogenesis of leukemia.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE21155
8 Samples
Download data: CEL, CHP

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