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Full record GDS4186

Lupus nephritis model response to sirolimus-induced mTOR inhibition (Mu11KsubA)

Analysis of kidney from sirolimus-treated NZB/W F1 females at 36 and 42 weeks of age. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been efficacious in the NZB/W model of lupus nephritis. Results provide insight into role of the mTOR pathway in autoimmune lupus nephritis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 agent, 2 disease state sets
Platform:
GPL75
Series:
GSE12024
16 Samples
Download data: CEL

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