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Full record GDS4528

KrasG12D pancreatic ductal epithelial cells deficient in PTEN

Analysis of primary pancreatic ductal epithelial cells (PDECs) established from 6-week-old Pdx1-Cre;LSL-KrasG12D L/+;Pten L/+ animals. Oncogenic KrasG12D and Pten deficiency cooperate to induce pancreatic ductal adenocarcinoma (PDAC). Results provide insight into molecular basis of PDAC development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE25828
8 Samples
Download data: CEL

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