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Full record GDS4533

Huntington's disease Hdh knock-out and knock-in embryonic stem cells

Analysis of embryonic stem cells without Hdh or with knock-in alleles with different Hdh CAG-polyglutamine repeat sizes. CAG-repeat length is inversely correlated with the age of onset of Huntington's disease (HD) symptoms in humans. Results provide insight into molecular mechanisms underlying HD.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 6 cell line, 3 genotype/variation, 7 other sets
Platform:
GPL1261
Series:
GSE26001
24 Samples
Download data: CEL

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