Chronic suppression of phosphodiesterase 10A effect on striatum and hippocampus - - GEO DataSets - NCBI

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Full record GDS4542

Chronic suppression of phosphodiesterase 10A effect on striatum and hippocampus

Analysis of C57BL6 striatum and hippocampus following chronic inhibition of PDE10A activity by dosing with PDE10A inhibitor TP-10 or by PDE10A knockout. PDE10A transcripts are significantly downregulated in Huntington's disease (HD) brain. Results provide insight into the molecular basis of HD.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation, 2 tissue sets

Platform:: GPL1261
Series:: GSE40377
42 Samples

Download data: CEL

DataSet

Accession:: GDS4542

ID:: 4542

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Chronic suppression of phosphodiesterase 10A effect on striatum and hippocampus
Chronic suppression of phosphodiesterase 10A effect on striatum and hippocampus
Accession: GDS4542

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