GEO DataSet Links for PMC (Select 1413522) - GEO DataSets

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Items: 2

Select item 2000042301.

Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice

(Submitter supplied) BACKGROUND: Lim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme. Conditional ablation of Lim1 in the metanephric mesenchyme blocks the formation of nephrons at the nephric vesicle stage, leading to the production of small, non-functional kidneys that lack nephrons. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1748
Platform:: GPL1261
8 Samples

Download data: CEL

Series

Accession:: GSE4230

ID:: 200004230

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 17482.

Homeobox Lim1 mutant nephron-deficient kidneys

Analysis of embryonic day 14.5 and 18.5 kidneys from Lim1 conditional mutants. Lim1 is a homoebox gene that is essential for nephrogenesis. The mutant is ablated for Lim1 in the metanephric mesenchyme, resulting in nephron deficient kidneys. Results identify genes expressed in developing nephrons.