GEO DataSet Links for PMC (Select 1849984) - GEO DataSets

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Links from PMC

Items: 4

Select item 2000080001.

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2746
Platform:: GPL1261
21 Samples

Download data: CEL

Series

Accession:: GSE8000

ID:: 200008000

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000063982.

Comparison between gene expression in heart from Lmna H222P homozygous and control mice

(Submitter supplied) The present research is devoted to the identification of gene(s) severely affected by LMNA mutations, leading to striated muscle laminopathies and more specifically the cardiomyopathy. For this purpose, we developped a large-scale gene expression approach on heart and skeletal tissues from Lmna H222P heterozygous Knock-In mouse model. Keywords: disease state modification

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
14 Samples

Download data: CEL

Series

Accession:: GSE6398

ID:: 200006398

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000063973.

Comparison between gene expression in heart from Lmna H222P heterozygous and control mice

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
15 Samples

Download data: CEL

Series

Accession:: GSE6397

ID:: 200006397

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 27464.

Lmna H222P homozygous and heterozygous mutant models of Emery-Dreifuss muscular dystrophy: hearts

Analysis of hearts of A-type lamin Lmna H222P homo-/heterozygous mutants. LMNA mutations lead to autosomal dominant and recessive Emery-Dreifuss muscular dystrophy which is characterized by dilated cardiomyopathy. Results provide insight into the role of LMNA in the development of cardiomyopathy.