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1.

Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-Associated Neurocognitive Disorders

(Submitter supplied) Antiretroviral therapy (ART) has reduced morbidity and mortality in HIV infection; however HIV-1-associated neurocognitive disorders (HAND) persist despite treatment. We used microarray analysis in post-mortem brain tissues to determine ART effectiveness in the brain and to identify molecular signatures of HAND under ART.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4231
Platform:
GPL570
35 Samples
Download data: CEL
Series
Accession:
GSE28160
ID:
200028160
2.
Full record GDS4231

Antiretroviral therapy effect on brain of patients with HIV-associated neurocognitive disorders

Analysis of postmortem brain of ART-treated, HIV-1-associated neurocognitive disorders (HAND) patients. ART reduces morbidity and mortality in HIV infection, but HAND persist despite treatment. Results provide insight into ART effectiveness in brain and into molecular signatures of HAND under ART.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 disease state sets
Platform:
GPL570
Series:
GSE28160
35 Samples
Download data: CEL

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