Skeletal muscle PGC-1a mediates mitochondrial, but not metabolic, changes during calorie restriction. - - GEO DataSets

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Skeletal muscle PGC-1a mediates mitochondrial, but not metabolic, changes during calorie restriction.

(Submitter supplied) Calorie restriction (CR) is a dietary intervention that extends lifespan and healthspan in a variety of organisms. CR improves mitochondrial energy production, fuel oxidation and reactive oxygen species scavenging in skeletal muscle and other tissues, and these processes are thought to be critical to the benefits of CR. PGC-1a is a transcriptional coactivator that regulates mitochondrial function and is induced by CR. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
26 Samples

Download data: CEL

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Accession:: GSE34773

ID:: 200034773

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