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Items: 2

1.

Treg specific Gata3 knock out array

(Submitter supplied) The transcription factor Foxp3 is indispensible for the differentiation and function of regulatory T cells (Treg cells). To gain insights into the molecular mechanisms of Foxp3 mediated gene expression we purified Foxp3 complexes and explored their composition. Biochemical and mass-spectrometric analyses revealed that Foxp3 forms multi-protein complexes of 400-800 kDa or larger and identified 361 associated proteins ~30% of which are transcription-related. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5164
Platform:
GPL8321
6 Samples
Download data: CEL
Series
Accession:
GSE39864
ID:
200039864
2.
Full record GDS5164

GATA-3 deficiency effect on regulatory T cell

Analysis of regulatory T (Treg) cells from mutants deficient for the transcription factor GATA-3. GATA-3 forms a complex with the transcription factor Fox3p, essential in the function of Treg cells. Results provide insight into the role of GATA-3 in the regulation of the Treg transcriptome.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL8321
Series:
GSE39864
6 Samples
Download data: CEL

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