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Targeted DNA demethylation using TALE-TET1 fusion proteins

(Submitter supplied) Recent large-scale studies have defined genomewide, cell type-specific patterns of DNA methylation, a modification known to be important for regulating gene expression in both normal development and disease states. However, determining the functional significance of specific methylation events remains a challenging problem due to the current lack of targeted methodologies for removing these modifications. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL15520
435 Samples
Download data: CSV, TXT
Series
Accession:
GSE50761
ID:
200050761

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