Format
Sort by

Send to:

Choose Destination

Links from PMC

Items: 2

1.

Steroid Receptor Coactivator 1 is an Integrator of Glucose and NAD(+)/NADH Homeostasis

(Submitter supplied) SRC-1 affects the expression of complex I of the mitochondrial electron transport chain, a set of enzymes responsible for the conversion of NADH to NAD(+). NAD(+) and NADH were subsequently identified as metabolites that underlie SRC-1's response to glucose deprivation. Knockdown of SRC-1 in glycolytic cancer cells abrogated their ability to grow in the absence of glucose consistent with SRC-1's role in promoting cellular adaptation to reduced glucose availability
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5418
Platform:
GPL570
8 Samples
Download data: CEL
Series
Accession:
GSE56843
ID:
200056843
2.
Full record GDS5418

Glucose effect on steroid receptor coactivator 1 deficient-A549 lung cancer epithelial cell line

Analysis of highly glycolytic A549 lung cancer cells depleted for steroid receptor coactivator SRC-1 and grown in the absence of glucose. SRC-1 promotes gluconeogenesis and glycemia. Results provide insight into the role of SRC-1 in glycolytic cancer cells undergoing glucose deprivation.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL570
Series:
GSE56843
8 Samples
Download data: CEL

Supplemental Content

db=gds|term=|query=1|qty=2|blobid=MCID_61ab7457f02bd60a2c483936|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center