GEO DataSet Links for PMC (Select 3968161) - GEO DataSets

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Items: 2

Select item 2000551621.

(Submitter supplied) We report here senescent changes in the structure and organization of the mucociliary pseudostratified epithelium of the mouse trachea and the main stem bronchi. We confirm previous reports of the graduate appearance of age-related, gland-like structures (ARGLS) in the submucosa, espeically in the intercartilage regions and carina. Immunohistochemistry shows these structures contain ciliated and secretory cells and Krt5+ basal cells, but not the myoepithelial cells or ciliated ducts typical of normal submucosal glands. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5412
Platform:: GPL1261
8 Samples

Download data: CEL

Series

Accession:: GSE55162

ID:: 200055162

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 54122.

Age effect on respiratory epithelium: distal trachea and carina region

Analysis of distal trachea and carina region of young (2 month) and old (14 month) C57Bl/6 females. Aging lungs are associated with a variety of structural and pathologic changes. Results provide insight into molecular mechanisms underlying age-related changes in respiratory epithelium.