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Items: 2

1.

Gene Expression Data in Human Monocyte-derived Dendritic Cell (MoDC) from Young and Aged Donors

(Submitter supplied) Dendritic cells (DCs) are major antigen-presenting cells that play a key role in initiating and regulating innate and adaptive immune responses. DCs are critical mediators of tolerance and immunity. The functional properties of DCs changes with age. The purpose of this study was to define the age-associated molecular changes in DCs by gene array analysis using Affymatrix GeneChips. We identified up and down-regulated gene expression changes in DC from aged donors compared to young donors.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5286
Platform:
GPL571
9 Samples
Download data: CEL
Series
Accession:
GSE58015
ID:
200058015
2.
Full record GDS5286

Monocyte-derived dendritic cells from young and aged donors

Comparison of dendritic cells (DCs) from young (20 to 27 years) and aged (77 to 87 years) donors. DCs are antigen-presenting cells important in initiating and regulating innate and adaptive immune responses. Results provide insight into the molecular basis of the decline in DC function with age.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL571
Series:
GSE58015
9 Samples
Download data: CEL

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