GEO DataSet Links for PMC (Select 4442869) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from PMC

Items: 2

Select item 2000531631.

Expression data from human monocyte-derived dendritic cells treated or not with interleukin 17A (IL-17A)

(Submitter supplied) IL-17A is a pro-inflammatory cytokine that promotes host defense against infections and contributes to the pathogenesis of chronic inflammatory diseases. Dendritic cells (DC) are antigen-presenting cells responsible for adaptive immune responses. Here, we report that IL-17A induces intense remodeling of lipid metabolism in human monocyte-derived DC, as revealed by microarrays analysis. In particular NR1H3/LXR-a and its target genes were significantly upregulated in response to IL-17A. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5817
Platform:: GPL570
9 Samples

Download data: CEL

Series

Accession:: GSE53163

ID:: 200053163

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 58172.

Interleukin 17A effect on monocyte-derived dendritic cells

Analysis of in vitro-generated dendritic cells (DCs) cultured with interleukin 17A (IL-17A) in the absence or presence of interferon-γ. IL-17A is involved in chronic inflammatory diseases. Results provide insight into the impact of IL-17A on DCs and the role of these DCs in inflammatory disease.