GEO DataSet Links for PMC (Select 4467398) - GEO DataSets

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Items: 2

Select item 2000624601.

Preclinical antitumor activity of ST7612AA1: a novel second generation oral histone deacetylase (HDAC) inhibitor

(Submitter supplied) assess the efficacy of ST7612AA1 oral pan-histone deacetylase inhibitor (HDACi), with respect to various solid and haematological tumors, and to characterize its mechanism of action

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5615
Platform:: GPL10558
12 Samples

Download data: TXT

Series

Accession:: GSE62460

ID:: 200062460

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 56152.

Oral histone deacetylase inhibitor ST7612AA1 effect on diffuse large B-cell lymphoma in vitro models

Analysis of lymphoma cell lines DOHH2 (derived from GCB-DLBCL) and TMD8 (derived from ABC-DLBCL) exposed to ST7612AA1 (300nM) for 8 hrs. ST7612AA1 is an oral thiol-based histone deacetylase inhibitor (HDACi). Results provide insight into the molecular mechanisms underlying ST7612AA1 action in DLBCL.