Format
Sort by

Send to:

Choose Destination

Links from PMC

Items: 3

1.

Mutant IDH inhibits HNF4a to disrupt hepatocyte differentiation and promote cholangiocarcinoma.

(Submitter supplied) Gene expression of mouse hepatoblasts (HBs) expressing IDH1 WT, IDH1 R132C, IDH2 WT, R172K and empty vector controls (N=2 cultures for each condition) grown on collagen-coated plates and IDH1 R132C and empty vector controls on uncoated plates were evaluated using Affymetrix Mouse 430Av2 DNA microarrays that were processed at the Dana-Farber Cancer Institute core facility (http://macf-web.dfci.harvard.edu/) using their standard protocol. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS5676 GDS5677
Platform:
GPL8321
14 Samples
Download data: CEL
Series
Accession:
GSE57002
ID:
200057002
2.
Full record GDS5677

Mutant isocitrate dehydrogenase 1 effect on hepatoblasts grown on uncoated plates

Analysis of mutant IDH1 (R132C)-expressing hepatoblasts that were grown on uncoated plates to induce hepatocyte differentiation. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into the role of IDH1 in hepatocyte differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL8321
Series:
GSE57002
4 Samples
Download data: CEL
3.
Full record GDS5676

Mutant isocitrate dehydrogenase 1 and 2 effect on hepatoblasts grown on collagen-coated plates

Analysis of hepatoblasts expressing mutant IDH1 (R132C) and mutant IDH2 (R172K) grown on collagen-coated plates. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into molecular pathways by which IDH mutations lead to tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 genotype/variation sets
Platform:
GPL8321
Series:
GSE57002
10 Samples
Download data: CEL
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=2|blobid=MCID_61f001a166dbb977db598e3a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center