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Items: 3

1.

DNA methylome analyses implicate fallopian tube as the tissue of origin for high grade serous ovarian cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array; Methylation profiling by high throughput sequencing
Platforms:
GPL13534 GPL16791
27 Samples
Download data: IDAT, TXT
Series
Accession:
GSE81228
ID:
200081228
2.

DNA methylome analyses implicate fallopian tube as the tissue of origin for high grade serous ovarian cancer [seq]

(Submitter supplied) The cell and tissue of origin of high grade serous ovarian cancer (HGSC) is controversial. While the disease was traditionally assumed to arise from the ovarian surface epithelium (OSE), recent work supports an alternative model implicating the fallopian tube fimbriae epithelium (FTE). We used comparative DNA methylome analyses as a means to test these two competing models, hypothesizing that the HGSC methylome should more closely resemble its tissue of origin. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL16791
7 Samples
Download data: TXT
Series
Accession:
GSE81227
ID:
200081227
3.

DNA methylome analyses implicate fallopian tube as the tissue of origin for high grade serous ovarian cancer [array]

(Submitter supplied) The cell and tissue of origin of high grade serous ovarian cancer (HGSC) is controversial. While the disease was traditionally assumed to arise from the ovarian surface epithelium (OSE), recent work supports an alternative model implicating the fallopian tube fimbriae epithelium (FTE). We used comparative DNA methylome analyses as a means to test these two competing models, hypothesizing that the HGSC methylome should more closely resemble its tissue of origin. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
20 Samples
Download data: IDAT
Series
Accession:
GSE81224
ID:
200081224
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