GEO DataSet Links for PMC (Select 8857816) - GEO DataSets

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Items: 3

Select item 2001841951.

Placental exosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL30209 GPL11154
12 Samples

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Series

Accession:: GSE184195

ID:: 200184195

PubMed Full text in PMC Similar studies

Select item 2001841942.

Placental exosomes polarize human monocyte-derived macrophages to a decidual M2-like macrophage phenotype

(Submitter supplied) Macrophages are abundant in uterine mucosa during the peri-implantation phase and early pregnancy. Decidual macrophages display dynamic changes alone with pregnancy progress: During the peri-implantation phase, macrophages displayed a pro-inflammatory phenotype which facilitates embryo implantation. While, In the late firster trimester and second trimester, decidual macrophages are anti-proinflammatory which are helpful to pregnancy maintenance. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: TXT

Series

Accession:: GSE184194

ID:: 200184194

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001840203.

Human placental exosomes induce maternal systemic immune tolerance in a monocyte-dependent manner

(Submitter supplied) Maternal immune tolerance toward to the semi-allograft fetus is a prerequisite condition for successful pregnancy. However, the role of maternal monocytes in the induction of systemic immune tolerance is poorly understood. Here we report that placenta facilitates maternal immune tolerance by extruding exosomes. Maternal monocytes were transformed into an immunosuppressive phenotype after taking up exosomes. more...