GEO DataSet Links for SRA (Select 11137032) - GEO DataSets

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Items: 2

Select item 3046243771.

Femoral homogenate - DO mouse 387

Organism:: Mus musculus

Source name:: Femur

Platform:: GPL19057
Series:: GSE152708

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Accession:: GSM4624377

ID:: 304624377

SRA Run Selector

Select item 2001527082.

Systems genetic analysis in Diversity Outbred mice informs human bone mineral density GWAS and identifies Qsox1 as a novel determinant of bone strength

(Submitter supplied) Genome-wide association studies (GWASs) for osteoporotic traits have identified over 1000 associations; however, their impact has been limited by the difficulties of causal gene identification and a strict focus on bone mineral density (BMD). Here, we used Diversity Outbred (DO) mice to directly address these limitations by performing the first systems genetics analysis of over 50 complex skeletal phenotypes. more...