GEO DataSet Links for SRA (Select 15179045) - GEO DataSets

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Items: 2

Select item 3054193021.

Naïve KO CD8+T cells rep1

Organism:: Mus musculus

Source name:: CD8+T cells

Platform:: GPL13112
Series:: GSE179491 GSE179492

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Sample

Accession:: GSM5419302

ID:: 305419302

SRA Run Selector

Select item 2001794912.

Brd4 regulates the homeostasis of CD8+ T-lymphocytes and their proliferation in response to antigen stimulation [RNA-seq]

(Submitter supplied) Purpose: The goals of this study are to compare the differentially expressed genes between in wild type and Brd4-/- CD8+T cells. Methods: RNA extracted from wild type and Brd4-/- CD8+T cells was used to generate RNA-seq library，followed by sequencing. Results: In naïve CD8+T cells, Brd4 deletion casued 956 downregulated genes and 841 upregulated genes. In in vitro-activated CD8+T cells（18hr），Brd4 deletion resulted in 1182 downregulated genes and 789 upregulated genes. more...