GEO DataSet Links for SRA (Select 16042602) - GEO DataSets

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Items: 2

Select item 3055716871.

B181: dsRdRP1_rep3

Organism:: Ixodes scapularis

Source name:: Ixodes scapularis embryonic 6 (ISE6) cells

Platform:: GPL30611
Series:: GSE183810

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Accession:: GSM5571687

ID:: 305571687

SRA Run Selector

Select item 2001838102.

RNA-dependent RNA polymerases in the black-legged tick produce Argonaute-dependent small RNAs and regulate genes

(Submitter supplied) Small regulatory RNAs (sRNAs) are involved in anti-viral defense and gene regulation. Although RNA-dependent RNA Polymerases (RdRPs) play essential roles in sRNA biogenesis in nematodes, plants and fungi, their involvement in other animals remains controversial. We identify abundant classes of ~22nt sRNAs that require specific combinations of RdRPs and sRNA effector proteins (Argonautes or AGOs) expressed in the tick ISE6 cell line. more...