GEO DataSet Links for SRA (Select 16934207) - GEO DataSets

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Links from SRA

Items: 2

Select item 3056121511.

M0_1

Organism:: Mus musculus

Source name:: Bone marrow

Platform:: GPL21493
Series:: GSE185375 GSE185380

Download data: BW

Sample

Accession:: GSM5612151

ID:: 305612151

SRA Run Selector

Select item 2001853752.

Multi-omics approaches reveal TNF-mediated inhibition of tissue reparative macrophages is via a gene-selective transcriptional mechanism (ATAC-Seq)

(Submitter supplied) Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis and Crohn’s Disease. Previously, we and others found that TNF blocks the emergence and function of alternatively-activated or M2 macrophages involved in wound healing and tissue-reparative functions. Conceivably, anti-TNF drugs could mediate their protective effects in part by an altered balanced of macrophage activity. more...