GEO DataSet Links for SRA (Select 2379632) - GEO DataSets

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Items: 2

Select item 3020988711.

22_CP_240

Organism:: Streptococcus pneumoniae D39; Homo sapiens

Source name:: A549_capsular mutant, more adherent_240m

Platform:: GPL21685
Series:: GSE79595

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Accession:: GSM2098871

ID:: 302098871

SRA Run Selector

Select item 2000795952.

Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection

(Submitter supplied) BACKGROUND: Streptococcus pneumoniae, the pneumococcus, is the main etiological agent of pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial cells. The exact transcriptional changes occurring in both host and microbe during infection are unknown. Here, we developed a time-resolved infection model of human lung alveolar epithelial cells by S. pneumoniae and assess the resulting transcriptome changes in both organisms simultaneously by using dual RNA-seq. more...