GEO DataSet Links for SRA (Select 260074) - GEO DataSets

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Items: 2

Select item 3010206461.

mouse_a_skm

Organism:: Mus musculus

Source name:: mouse_skm

Platform:: GPL13112
Series:: GSE41637

Download data: GTF

Sample

Accession:: GSM1020646

ID:: 301020646

SRA Run Selector

Select item 2000416372.

Evolutionary dynamics of gene and isoform regulation in mammalian tissues

(Submitter supplied) Most mammalian genes produce multiple distinct mRNAs through alternative splicing, but the extent of splicing conservation is not clear. To assess tissue-specific transcriptome variation across mammals, we sequenced cDNA from 9 tissues from 4 mammals and one bird in biological triplicate, at unprecedented depth. We find that while tissue-specific gene expression programs are largely conserved, alternative splicing is well conserved in only a subset of tissues and is frequently lineage-specific. more...