GEO DataSet Links for SRA (Select 3454759) - GEO DataSets

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Links from SRA

Items: 2

Select item 3024026241.

shControl_Rep3

Organism:: Mus musculus

Source name:: Embryonic Dorsal Root Ganglia_shControl

Platform:: GPL17021
Series:: GSE90476 GSE90477

Download data: TXT

Sample

Accession:: GSM2402624

ID:: 302402624

SRA Run Selector

Select item 2000904762.

miRNA-9 regulates axon regeneration through the transcriptional regulator REST and the epigenetic factor UHRF1 [RNA-seq]

(Submitter supplied) Injured sensory neurons successfully activate a pro-regenerative transcriptional program to enable axon regeneration and functional recovery, but the roles of genes that are inactivated after injury remain poorly understood. Analysis of the miRNA expression profile triggered by axon injury revealed down-regulation of the neural development associated miRNA, miR-9. A target of miR-9 is the critical epigenetic regulator involved in DNA methylation, ubiquitin-like containing PHD ring finger 1 (UHRF1), which increased after injury to promote axon regeneration. more...