GEO DataSet Links for SRA (Select 35127) - GEO DataSets

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Items: 2

Select item 3006107471.

G9a_f_f_4h_pIC_H3K9me2_redo

Organism:: Mus musculus

Source name:: MEF

Platform:: GPL9250
Series:: GSE22102 GSE24826

Download data: WIG

Sample

Accession:: GSM610747

ID:: 300610747

SRA Run Selector

Select item 2000221022.

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response (sequencing)

(Submitter supplied) Effective anti-viral immunity depends on the ability of infected cells or cells triggered with virus-derived nucleic acids to produce type I interferon (IFN), which activates transcription of numerous antiviral genes. However, disproportionately strong or chronic IFN expression is a common cause of inflammatory and autoimmune diseases. Here we describe an epigenetic mechanism that determines cell-type specific differences in IFN and IFN-stimulated gene expression in response to exogenous signals. more...