GEO DataSet Links for SRA (Select 5231645) - GEO DataSets

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Items: 2

Select item 3030431421.

Lrp::kanR Minimal logarithmic rep2-RNAseq

Organism:: Escherichia coli

Source name:: Culture lysate

Platform:: GPL21222
Series:: GSE111874

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Sample

Accession:: GSM3043142

ID:: 303043142

SRA Run Selector

Select item 2001118742.

Escherichia coli Lrp regulates one-third of the genome via direct, cooperative, and indirect paths

(Submitter supplied) The global regulator Lrp plays a crucial role in regulating metabolism, virulence and motility in response to environmental conditions. Lrp has previously been shown to activate or repress approximately 10% of genes in Escherichia coli. However, the full spectrum of targets, and how Lrp acts to regulate them, has stymied earlier study. We have combined matched ChIP-seq and RNA sequencing under nine physiological conditions to map the binding and regulatory activity of Lrp as it directs responses to nutrient abundance. more...