txid10116[orgn] AND "strain Fischer F344"[All Fields] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 1 to 20 of 112

<< First< Prev

Page of 6

Select item 2000501511.

Expression data from 15 month old rat brain subjected to fructose fetal programming

(Submitter supplied) Fructose has recently been observed to affect brain metabolism and cognitive function in adults. However, possible fetal programming of brain metabolism induced by gestational fructose has not been examined. We evaluated mitochondrial function in the brain of aging (15 month) male offspring of Fischer F344 rat dams fed either a high-fructose diet (50% energy from fructose) or a matched control diet during early life (gestation and lactation). more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6247
13 Samples

Download data: CEL

Series

Accession:: GSE50151

ID:: 200050151

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000484922.

Effect of treatment for three months with chemical carcinogen and non-carcinogens on liver miRNAome

(Submitter supplied) Here, we examined the liver microRNA profile of male Fischer rats exposed through their diet to genotoxic (2-acetylaminofluorene) and epigenetic (phenobarbital, diethylhexylphthalate, methapyrilene HCL, monuron, and chlorendic acid) chemical hepatocarcinogens, as well as to non-hepatocarcinogenic treatments (benzophenone, and diethylthiourea) for three months. The aim of the study was to investigate how liver miRNA profiles relate to mode of action and carcinogenic potential of chemicals.

Organism:: Rattus norvegicus

Type:: Non-coding RNA profiling by array

Platform:: GPL14889
38 Samples

Download data: TXT

Series

Accession:: GSE48492

ID:: 200048492

Select item 2000484893.

Dose and temporal effects of Phenobarbital on the liver miRNAome of male Fischer rats

(Submitter supplied) Male Fischer rats were fed a control diet or a diet supplemented with 50, 500 or 1000 ppm Phenobarbital. The 500 and 1000 ppm PB doses induced a transient hyperplasia and a sustained hepatomegaly in treated animals. The animals were sacrificed and liver miRNAome was profiled in three animals per group after 1, 3, 7, and 14 days of treatment. The aim was to investigate the time and dose dependent effects of phenobarbital treatment on the liver miRNAome

Organism:: Rattus norvegicus

Type:: Non-coding RNA profiling by array

Platform:: GPL14889
48 Samples

Download data: TXT

Series

Accession:: GSE48489

ID:: 200048489

Select item 2000248014.

Cultured OEC versus cultured SC and versus native OEC

(Submitter supplied) This microarray study aimed at identifying the differences in the global gene expression growth program of adult cultured olfactory ensheathing cells (cOEC) (from the olfactory bulb) versus adult cultured Schwann cells (SC) (from the sciatic nerve) and versus adult OEC directly dissected from the olfactory nerve layer (nOEC). The aim of the comparison between cOEC and SC is to define intrinsic molecular differences that distinguish cOEC from SC (both cell types support neuronal regeneration). more...