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Items: 1 to 20 of 36

1.

MiRNAs array after SH3BP2 silencing in Gastrointestinal stromal tumor cells

(Submitter supplied) Silencing of the adaptor SH3BP2 impairs Gastrointestinal stromal tumors growth through miRNAs We dissected SH3BP2 pathway in Gastrointestinal Stromal Tumor cells (GIST) performing a miRNA array in SH3BP2-silenced GIST cells
Organism:
Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL21599
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE213777
ID:
200213777
2.

miRNA profile in the hippocampus of APP/PS1 transgenic mice

(Submitter supplied) To explore the miRNAs associated with the memory deficits in Alzheimer's disease, we detected the miRNA profiles in the hippocampus of 6-month-old male APPswe/PS1dE9 (APP/PS1) mice and age-matched wild type C57BL/6 mice.
Organism:
Human alphaherpesvirus 2; Human betaherpesvirus 6B; Merkel cell polyomavirus; Betapolyomavirus hominis; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
6 Samples
Download data: GPR
Series
Accession:
GSE138382
ID:
200138382
3.

Microarray-based miRNA expression,identified miRNAs that were regulated by KSHV vIRF1

(Submitter supplied) HUVECs were transduced with lentiviral vIRF1 or control lentivirus (pHAGE),microarray-based miRNA expression profiling was adopted and identified a set of miRNAs that were differentially expressed between vIRF1- and pHAGE-transduced HUVECs
Organism:
Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platforms:
GPL20712 GPL21439
6 Samples
Download data: TXT
Series
Accession:
GSE119034
ID:
200119034
4.

Profiling of microRNA expression in canine mammary cancer

(Submitter supplied) MicroRNAs may act as oncogenes or tumour suppressor genes, which make these small molecules potential diagnostic/prognostic factors and targets for anticancer therapies. On account of this, we performed large-scale profiling of microRNA expression in canine mammary cancer.
Organism:
Human alphaherpesvirus 2; Human betaherpesvirus 6B; Betapolyomavirus hominis; Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Human immunodeficiency virus 1; Merkel cell polyomavirus; Canis lupus familiaris; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
171 Samples
Download data: TXT
Series
Accession:
GSE103093
ID:
200103093
5.

MicroRNAs expression different in Serum between Trauma-induced osteonecrosis of the femoral head (TIONFH) and healing patients

(Submitter supplied) We recently showed that microRNA different profile from Trauma-induced osteonecrosis of the femoral head (TIONFH) and healing patients.
Organism:
Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
20 Samples
Download data: GPR
Series
Accession:
GSE89587
ID:
200089587
6.

Human microRNA (miRNA) expression during serum starvation

(Submitter supplied) The study aimed to identify the differentially regulated microRNAs during serum starvation. We identified miRNAs exhibiting altered expression in asynchronous, serum starved and serum re-supplemented human cells. We identified several miRNAs that were upregulated following serum starvation and downregulated upon serum re-supplementation.
Organism:
Human alphaherpesvirus 2; Human betaherpesvirus 6B; Merkel cell polyomavirus; Betapolyomavirus hominis; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL23981
6 Samples
Download data: TXT
Series
Accession:
GSE103436
ID:
200103436
7.

Dysregulation of a miR-23b/27b-p53 axis impairs muscle differentiation in humans with type 2 diabetes

(Submitter supplied) Impaired skeletal muscle function is a central feature in the pathophysiology of type 2 diabetes (T2DM). The disease phenotype could be due to immature muscle cell development, which in turn may occur as the result of disturbed microRNA-mediated regulation of muscle differentiation in T2DM. To address this hypothesis, we assessed global miRNA expression during in vitro differentiation of muscle stem cells derived from T2DM patients and healthy controls. more...
Organism:
Human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Human alphaherpesvirus 2; Saimiriine gammaherpesvirus 2; Betapolyomavirus hominis; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL22371
47 Samples
Download data: TXT
Series
Accession:
GSE86069
ID:
200086069
8.

microRNA expression profiling in human colon cancer

(Submitter supplied) Using the highly sensitive miRCURY LNA™ microRNA array, we screened 3100 microRNAs abundant in the human colon cancer and Adjacent normal gastric mucosa tissues, and the function of differentially expressed microRNAs were analyzed by bioinformatics. The enrichment results indicated that these microRNAs perhaps participated in the occurrence and development process of colon cancer. In this study, three cases of colon cancer were used to acquire the microRNA expression profiling, and qPCR was employed to confirm the results of microRNA chip. more...
Organism:
Macacine alphaherpesvirus 1; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Merkel cell polyomavirus; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
6 Samples
Download data: GPR
Series
Accession:
GSE101502
ID:
200101502
9.

Plasma MicroRNA alterations between EGFR-activating mutational NSCLC patients with and without primary resistance to TKI

(Submitter supplied) The aim of the present study was to examine differentially expressed miRNAs in plasma between EGFR-TKIs sensitive and EGFR-TKIs primary resistance patients.
Organism:
Homo sapiens; Human betaherpesvirus 5; Betapolyomavirus hominis; Macacine alphaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); Human gammaherpesvirus 8; Betapolyomavirus macacae; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human gammaherpesvirus 4; Human betaherpesvirus 6B
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
8 Samples
Download data: GPR
Series
Accession:
GSE99143
ID:
200099143
10.

microRNA expression in facet cartilage degeneration

(Submitter supplied) Osteoarthritis (OA) of spine (facet joints; FJ) is one of the major causes of severe low back pain and disability worldwide. The degeneration of facet cartilage is a hallmark of FJ OA. However, endogenous mechanisms that initiate degeneration of facet cartilage are unknown and there are no disease-modifying therapies to stop FJ OA. In this study we performed microRNA array analysis to identify differentially expressed microRNAs in facet cartilage from patients with FJ OA compared to facet cartilage from patients with lumbar disc herniation (LDH).
Organism:
Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL21599
4 Samples
Download data: TXT
Series
Accession:
GSE79258
ID:
200079258
11.

microRNA expression profiling in human gastric cancer

(Submitter supplied) Using the highly sensitive miRCURY LNA™ microRNA array, we screened 3100 microRNAs abundant in the human gastric cancer and Adjacent normal gastric mucosa tissues, and the function of differentially expressed microRNAs were analyzed by bioinformatics. The enrichment results indicated that these microRNAs perhaps participated in the occurrence and development process of gastric cancer.
Organism:
Human alphaherpesvirus 2; Human betaherpesvirus 6B; Betapolyomavirus hominis; Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Human immunodeficiency virus 1; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
6 Samples
Download data: GPR
Series
Accession:
GSE78091
ID:
200078091
12.

Primary Human Osteoblasts miRNA array

(Submitter supplied) A microRNA array was performed using human primary osteoblasts (hOB) obtained from trabecular bone of postmenopausal women after knee replacement due to osteoarthritis in order to determine the miRNAs expressed in these osteoblastic cells.
Organism:
Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL20999
4 Samples
Download data: TXT, XLSX
Series
Accession:
GSE74211
ID:
200074211
13.

MiRNA Profiling of Whole Trabecular Bone: Identification of Osteoporosis-Related Changes in MiRNAs in Human Hip Bones

(Submitter supplied) MicroRNAs (miRNAs) are important regulators of gene expression, with documented roles in bone metabolism and osteoporosis, suggesting potential therapeutic targets. Our aim was to identify miRNAs differentially expressed in fractured vs nonfractured bones. Additionally, we performed a miRNA profiling of primary osteoblasts to assess the origin of these differentially expressed miRNAs. Total RNA was extracted from (a) fresh femoral neck trabecular bone from women undergoing hip replacement due to either osteoporotic fracture (OP group, n=6) or osteoarthritis in the absence of osteoporosis (Control group, n=6), matching the two groups by age and body mass index, and (b) primary osteoblasts obtained from knee replacement due to osteoarthritis (n=4). more...
Organism:
Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Betapolyomavirus hominis; Betapolyomavirus macacae; Macacine alphaherpesvirus 1; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus; Human alphaherpesvirus 2; Human betaherpesvirus 6B
Type:
Non-coding RNA profiling by array
Platform:
GPL20999
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE74209
ID:
200074209
14.

Rnase1 responsive miRNA

(Submitter supplied) To determine the importance of RNase1 on cellular miRNA function, we used a lentivirus system to stably express RNase1 in dicer wt and dicer ex5 RKO cells in serum free culture. RNase1 was found to govern miRNA that reside outside the pureview of Dicer. Assignment of RNase1 as miRNA-generating enzyme suggests that, like Dicer, RNaseA enzymes mediate essential physiological functions through regulatory RNA.
Organism:
Homo sapiens; Human betaherpesvirus 5; Saimiriine gammaherpesvirus 2; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human gammaherpesvirus 4; Human betaherpesvirus 6B; Macacine alphaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL20891
8 Samples
Download data: TXT
Series
Accession:
GSE72796
ID:
200072796
15.

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Human alphaherpesvirus 2; Human betaherpesvirus 6B; Betapolyomavirus macacae; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus hominis; Human gammaherpesvirus 4; Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platforms:
GPL20657 GPL20658
12 Samples
Download data: TXT
Series
Accession:
GSE70996
ID:
200070996
16.

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]

(Submitter supplied) Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cells engage and recruit nurturing cells is poorly characterised. Here we demonstrate that CLL cells secrete exosomes that are nanovesicles originating from the fusion of multivesicular bodies with the plasma membrane, to shuttle proteins, lipids, microRNAs (miR) and mRNAs to recipient cells. more...
Organism:
Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); Human gammaherpesvirus 8; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human betaherpesvirus 6B; Betapolyomavirus macacae; Homo sapiens; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL20658
6 Samples
Download data: TXT
Series
Accession:
GSE70995
ID:
200070995
17.

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 13]

(Submitter supplied) Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cells engage and recruit nurturing cells is poorly characterised. Here we demonstrate that CLL cells secrete exosomes that are nanovesicles originating from the fusion of multivesicular bodies with the plasma membrane, to shuttle proteins, lipids, microRNAs (miR) and mRNAs to recipient cells. more...
Organism:
Human alphaherpesvirus 1; Human betaherpesvirus 5; Human betaherpesvirus 6B; Betapolyomavirus macacae; Human alphaherpesvirus 2; Betapolyomavirus hominis; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL20657
6 Samples
Download data: TXT
Series
Accession:
GSE70994
ID:
200070994
18.

Let-7, mir-98 and mir-181 as biomarkers for cancer and schizophrenia

(Submitter supplied) Recent evidence supports a role of microRNAs in cancer and psychiatric disorders such as schizophrenia and bipolar disorder, through their regulatory role on the expression of multiple genes. The rather rare co-morbidity of cancer and schizophrenia is an old hypothesis which needs further research on microRNAs as molecules that might exert their oncosuppressive or oncogenic activity in the context of their role in psychiatric disorders The expression pattern of a variety of different microRNAs was investigated in patients (N=6) suffering from schizophrenia termed control, patients with a solid tumor (N=10) and patients with both schizophrenia and tumor (N=8). more...
Organism:
Macacine alphaherpesvirus 1; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human alphaherpesvirus 2; Lymphocryptovirus; Human betaherpesvirus 6B; Betapolyomavirus hominis; Rhadinovirus; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platforms:
GPL19677 GPL19676
24 Samples
Download data: TXT, XLS
Series
Accession:
GSE65143
ID:
200065143
19.

miRCURY LNA microRNA Array, 7th generation (miRBase 19; probeID version)

(Submitter supplied) Exiqon Array product number: 208500 Array version: 7th Gen Array batch number: 35013 miRBase version: 19 Protocol: See Exiqon website
Organism:
Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human betaherpesvirus 6B; Human gammaherpesvirus 8; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae
1 Series
6 Samples
Download data
Platform
Accession:
GPL23981
ID:
100023981
20.

Exiqon, miRCURY LNA microRNA array, 6th gen (hsa, mirbase 17, Gene ID version)

(Submitter supplied) Herpesvirus saimiri strain A11 Protocol: See Exiqon website
Organism:
Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human gammaherpesvirus 4; Saimiriine gammaherpesvirus 2; JC polyomavirus; Human immunodeficiency virus 1; Human betaherpesvirus 6B; Human gammaherpesvirus 8; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae
1 Series
47 Samples
Download data
Platform
Accession:
GPL22371
ID:
100022371
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