GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Human immunodeficiency virus

Type:

Expression profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing

Platforms:

GPL11154 GPL26648

29 Samples

Download data: NARROWPEAK, TXT

(Submitter supplied) In this study, we used a productive HIV infection model, consisting of the CD4+ SupT1 T cell line infected with a VSV-G pseudotyped HIVeGFP-based vector, to explore the transcriptomic and m6A/m5C epitranscriptomic lansdcape upon HIV infection, and compare it to mock-treated cells at 12h, 24h, and 36h post infection.

Organism:

Human immunodeficiency virus

Type:

Other

Platform:

GPL26648

2 Samples

Download data: NARROWPEAK

(Submitter supplied) In this study, we used a productive HIV infection model, consisting of the CD4+ SupT1 T cell line infected with a VSV-G pseudotyped HIVeGFP-based vector, to explore the transcriptomic and m6A/m5C epitranscriptomic lansdcape upon HIV infection, and compare it to mock-treated cells at 12h, 24h, and 36h post infection.

Organism:

Human immunodeficiency virus

Type:

Methylation profiling by high throughput sequencing

Platform:

GPL26648

9 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Staphylococcus aureus; Onchocerca volvulus; Yellow fever virus; Chikungunya virus; Streptococcus sp. 'group B'; Mycobacterium tuberculosis; Homo sapiens; Dengue virus; Human immunodeficiency virus; Respiratory syncytial virus; Zika virus; Bordetella pertussis; Plasmodium falciparum

Type:

Protein profiling by protein array

Platform:

GPL29530

804 Samples

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(Submitter supplied) Breastfeeding provides defense against infectious disease during early life. The mechanisms underlying this protection are complex but likely include the vast array of immune cells and components, such as immunoglobulins, in milk. Simply characterizing the concentrations of these bioactives, however, provides only limited information regarding their potential relationships with disease risk in the recipient infant. more...

Organism:

Staphylococcus aureus; Yellow fever virus; Streptococcus sp. 'group B'; Onchocerca volvulus; Dengue virus; Human immunodeficiency virus; Respiratory syncytial virus; Zika virus; Chikungunya virus; Bordetella pertussis; Mycobacterium tuberculosis; Plasmodium falciparum; Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL29530

402 Samples

Download data: TXT

(Submitter supplied) Breastfeeding provides defense against infectious disease during early life. The mechanisms underlying this protection are complex but likely include the vast array of immune cells and components, such as immunoglobulins, in milk. Simply characterizing the concentrations of these bioactives, however, provides only limited information regarding their potential relationships with disease risk in the recipient infant. more...

Organism:

Staphylococcus aureus; Yellow fever virus; Chikungunya virus; Streptococcus sp. 'group B'; Onchocerca volvulus; Dengue virus; Human immunodeficiency virus; Zika virus; Bordetella pertussis; Mycobacterium tuberculosis; Plasmodium falciparum; Homo sapiens; Respiratory syncytial virus

Type:

Protein profiling by protein array

Platform:

GPL29530

402 Samples

Download data: TXT

(Submitter supplied) Thermostable reverse transcriptases are workhorse enzymes underlying nearly all modern techniques for RNA structure mapping and for transcriptome-wide discovery of RNA chemical modifications. Despite their wide use, these enzymes’ behaviors at chemical modified nucleotides remain poorly understood. Wellington-Oguri et al. recently reported an apparent loss of chemical modification within putatively unstructured polyadenosine stretches modified by dimethyl sulfate or 2’ hydroxyl acylation, as probed by reverse transcription. more...

Organism:

synthetic construct; Human immunodeficiency virus

Type:

Other

Platforms:

GPL17769 GPL28440

3 Samples

Download data: TAR

(Submitter supplied) Illumina sequencing data used in HIV-CRISPR screen with an ISG-specific sgRNA library (PIKAHIV) to find genes that block infection by the N74D and P90A HIV-1 capsid mutant viruses in THP-1 monocytic cells. For more information on the library and approach see Ohainle et al. eLife 2018 (PMID: 30520725). All screens performed here were done in a clonal ZAP-KO cell line (ZAP may inhibit the HIV-CRISPR vector used in the screen). more...

Organism:

Human immunodeficiency virus; Homo sapiens

Type:

Other

Platforms:

GPL16791 GPL25457

12 Samples

Download data: TXT

(Submitter supplied) In this GEO submission we include the PA-m6A-seq and PA-m5C-seq datasets for HIV in CEM & 293T cells

Organism:

Human immunodeficiency virus

Type:

Expression profiling by high throughput sequencing; Other

Platform:

GPL26648

11 Samples

Download data: BED

(Submitter supplied) Interferon (IFN) inhibits HIV replication by inducing an array of antiviral effectors. Here we describe a novel CRISPR knockout screening approach to identify the ensemble of these HIV restriction factors. We assembled a CRISPR sgRNA library specific for Interferon Stimulated Genes (ISGs) into a modified lentiviral vector that allows for packaging of sgRNA-encoding genomes in trans into budding HIV-1 particles. more...

Organism:

Homo sapiens; Human immunodeficiency virus

Type:

Other

Platforms:

GPL25457 GPL16791

18 Samples

Download data: FA, TXT

(Submitter supplied) Low aerobic exercise capacity is a risk factor for diabetes and strong predictor of mortality; yet some individuals are exercise resistant, and unable to improve exercise capacity through exercise training. To test the hypothesis that resistance to aerobic exercise training underlies metabolic disease-risk, we used selective breeding for 15 generation to develop rat models of low- and high-aerobic response to training. more...

Organism:

Homo sapiens; Human betaherpesvirus 5; Human immunodeficiency virus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus macacae; Rattus norvegicus; Murid betaherpesvirus 1; JC polyomavirus; Mus musculus; Human alphaherpesvirus 1

Type:

Non-coding RNA profiling by array

Platform:

GPL18716

12 Samples

Download data: GPR

(Submitter supplied) organism: Multiple pathogens Protocol: https://antigendiscovery.com/adi-proteome-microarray-technology/

Organism:

Bordetella pertussis; Staphylococcus aureus; Streptococcus sp. 'group B'; Mycobacterium tuberculosis; Plasmodium falciparum; Onchocerca volvulus; Yellow fever virus; Dengue virus; Human immunodeficiency virus; Respiratory syncytial virus; Chikungunya virus; Zika virus

3 Series

804 Samples

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(Submitter supplied) Spotted Locked Nucleic Acid (LNA) on glass slides. Protocol: http://www.exiqon.com/ls/Documents/Scientific/miRCURY-LNA-microRNA-Array-5th-gen-hsa-mmu-rno-manual.pdf

Organism:

Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus hominis; Betapolyomavirus macacae

1 Series

12 Samples

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