GEO DataSets

(Submitter supplied) Plasmodium parasites within mosquitoes are exposed to various physiological processes, such as blood meal digestion activity, the gonotrophic cycle, and host responses preventing the entry of parasites into the midgut wall. However, when in vitro-cultured ookinetes are injected into the hemocoel of mosquitoes, Plasmodium parasites are not affected by the vertebrate host’s blood contents and do not pass through the midgut epithelial cells. more...

Organism:

Anopheles stephensi

Type:

Expression profiling by high throughput sequencing

Platform:

GPL31974

8 Samples

Download data: TXT

(Submitter supplied) We report the RNA-seq based analyses of the transcriptional changes in the Anopheles stephensi transcriptome at 7d after blood feeding with CSPwt or CSPmut plasmodium.

Organism:

Anopheles stephensi

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30224

4 Samples

Download data: TXT

(Submitter supplied) Mayaro virus (MAYV) is a mosquito-borne Alphavirus responsible for outbreaks in South America and the Caribbean. In this study we infected Anopheles stephensi with MAYV and sequenced mRNA and small RNA to understand how MAYV infection impacts gene transcription and the expression of small RNAs in the mosquito vector. Genes involved with innate immunity and autophagy are regulated in response to MAYV infection of An. more...

Organism:

Anopheles stephensi

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL29653

36 Samples

Download data: CSV, XLSX

(Submitter supplied) Malaria is as one of the most debilitating mosquito-borne global health burdens. While much of the malaria and mosquito-borne disease attention have focused on Africa, South East Asia accounts for a sizable portion of the malaria global burden. Moreover, about 50% of the Asian malaria incidence and deaths have been from India. The completion of genome sequence of Anopheles stephensi, a major malaria vector in Asia, offers new opportunities for global health innovation, not to mention for progress in deciphering the vectorial ability of this mosquito species at a molecular level. more...

Organism:

Anopheles stephensi

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23543

4 Samples

Download data: GTF, TXT

(Submitter supplied) A piggyBac transposon-based gene trap element was transformed into the Asian malaria vector, Anopheles stephensi, and remobilized using the jumpstarter approach using genetic crosses. Individuals that displayed a gene trap remobilization event were then photodocumented and their RNA and DNA complements were extracted. The DNA compelement was used to determine the genomic insertion site, while the RNA was used to determine the transcript coverage of the genes into which the transposons inserted. more...

Organism:

Anopheles stephensi

Type:

Other

Platform:

GPL21539

1 Sample

Download data: GTF, TXT

(Submitter supplied) Mosquitoes possess an innate immune system that is capable of limiting infection by a variety of pathogens, including the Plasmodium spp. parasites responsible for human malaria. The Anopheles immune deficiency (IMD) innate immune signaling pathway confers resistance to Plasmodium falciparum. While some previously identified Anopheles anti-Plasmodium effectors are regulated through signaling by Rel2, the transcription factor of the IMD pathway, many components of this defense system remain uncharacterized. more...

Organism:

Anopheles stephensi

Type:

Expression profiling by array

Platform:

GPL18912

4 Samples

Download data: TXT

(Submitter supplied) Agilent

Organism:

Anopheles stephensi

1 Series

4 Samples

Download data: TXT