txid4932[orgn] AND "strain CY3003"[All Fields] - GEO DataSets

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Items: 2

Select item 2000185911.

Gene profiling of TRA1 and tra1-L3733A

(Submitter supplied) Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the phosphatidylinositol 3-kinase kinase family that contain a C-terminal PI3K domain followed by a 35-residue FATC domain. We analyzed alleles with single residue changes in the FATC domain. Of these tra1-L3733A had the most pronounced effects, resulting in phenotypes similar but not identical to those resulting from mutations in the PI3K domain or SAGA or NuA4 components. more...