GEO DataSets

(Submitter supplied) In C. elegans worms, epigenetic information transmits transgenerationally. Still, it is unknown whether the effects transfer to the next generation inside or outside of the nucleus. Here we use the tractability of gene-specific double-stranded RNA-induced silencing to demonstrate that RNAi can be inherited independently of any nuclear factors via mothers that are genetically engineered to transmit only their ooplasm but not the oocytes’ nuclei to the next generation. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL19757

23 Samples

Download data: CSV

(Submitter supplied) The objective of this work was to determine the effectiveness of cross-hybridization of gDNA from five native soil nematodes to an Affymetrix Caenorhabditis elegans tiling array. Cross-hybridization experiments using C. briggsae, for which genome information is available, allowed hybridisation intensities to be correlated with known sequence differences. Initial analysis of data by conventional array-based Comparative Genomic Hybridization (aCGH) techniques at the chip level lead to misleading results due to an artefact from the combination of scaling, bandwidth smoothing, and differential GC content in exon and intron regions. more...

Organism:

Oscheius sp. FVV-2; Oscheius tipulae; Acrobeloides sp. MAH-2010; Caenorhabditis briggsae; Caenorhabditis elegans; Mesorhabditis sp. MAH-2010; Chiloplacus sp. MAH-2010

Type:

Genome variation profiling by genome tiling array

Platform:

GPL5634

8 Samples

Download data: CEL, CHP, TXT

(Submitter supplied) The Males Experiment: This experiment was done to test the sensitivity of our array in detecting single copy losses of probes to the X chromosome. Males (XO) have just one X chromosome, while hermaphrodites (XX) have two. CB4856 and JU258: This experiment was done to determine the natural copy number variation that exists in a wild C. elegans isolate. Extensive natural copy number variation exists in this strain. more...

Organism:

Caenorhabditis elegans

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL4553 GPL4552 GPL4551

14 Samples

Download data: PAIR, TXT