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Items: 3

1.

Comparison of small RNA levels in Dicer helicase mutants

(Submitter supplied) Years after the discovery that Dicer is a key enzyme in gene-silencing, the role of its helicase domain remains enigmatic. Here we show that this domain is critical for accumulation of certain endogenous small interfering RNAs (endo-siRNAs) in C. elegans. The domain is required for the production of the direct products of Dicer, or primary endo-siRNAs, and consequently, affects levels of downstream intermediates, the secondary endo-siRNAs. more...
Organism:
Caenorhabditis elegans
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL9269
3 Samples
Download data: TXT
Series
Accession:
GSE20336
ID:
200020336

PubMed Full text in PMC Similar studies SRA Run Selector

2.

dcr-1(-/-)K39A_2

Organism:
Caenorhabditis elegans
Source name:
whole organism
Platform:
GPL9269
Series:
GSE20336
Download data: TXT
Sample
Accession:
GSM509584
ID:
300509584

SRA Run Selector

3.

dcr-1(-/-)K39A_1

Organism:
Caenorhabditis elegans
Source name:
whole organism
Platform:
GPL9269
Series:
GSE20336
Download data: TXT
Sample
Accession:
GSM509583
ID:
300509583

SRA Run Selector

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db=gds|term=txid6239[orgn]%20AND%20%22strain%20BB93%20dcr-1%20ok247%20uuEx18%20dcr-1%20K39A%20,%20dpy-30%20mCherry%22[All%20Fields]|query=1|qty=2|blobid=MCID_66231c504c13c13a0641874d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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