Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 105452

1.

K27M and K36M mutations on non canonical Histone 3.3 promote redistribution of antagonistic chromatin marks, disrupted development, and tumorigenesis

(Submitter supplied) We conducted RNA-seq analysis to identify genes that are differentially expressed in H3K27M and H3K36M oncohistones compared to wt and control eye tissue (eye discs), followed by smRNA-seq profiling based on our results and to confirm upregulation of piRNAs
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL25244 GPL21306
68 Samples
Download data: BEDGRAPH, BW
Series
Accession:
GSE140979
ID:
200140979
2.

Hox binding in Drosophila third instar larval wing imaginal discs

(Submitter supplied) Genome-wide binding of Hox proteins in Drosophila melanogaster third instar larvae: Ubx, AbdA, AbdB
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL15641
9 Samples
Download data: PAIR, SGR, TXT
Series
Accession:
GSE65275
ID:
200065275
3.

Gene expression: nubGal4;UAS-Hox vs. nubGal4;UAS-eGFP Drosophila third instar larval wing imaginal discs

(Submitter supplied) Comparison of the four Hox genes, Ubx, AbdA, AbdB and Labial, ectopically expressed in the wing imaginal disc during the Drosophila third instar larval developmental stage.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL14121
20 Samples
Download data: TXT
Series
Accession:
GSE58106
ID:
200058106
4.

Next generation sequencing of isolated R5 ellipsoid body neurons of Drosophila in the morning and evening with and without sleep deprivation

(Submitter supplied) Purpose: After identifying a difference in the response to sleep deprivation between the morning and evening, we assayed gene expression in a key homeostatic circuit in the Drosophila brain: the R5 ellipsoid body neurons. We sought to identify changes in gene expression in this circuit that are critical for the behavioral output. Methods: Flies expressing GFP via a restrictive R5 driver were entrained to a 12:12 light:dark paradigm at 25C. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25244
12 Samples
Download data: CSV, H5
Series
Accession:
GSE186076
ID:
200186076
5.

Transcriptomes of the developing larval ovaries of Drosophila melanogaster during terminal filament formation

(Submitter supplied) Insect ovaries are made up of tubular egg producing subunits called ovarioles, whose number largely determines the number of eggs that can be potentially laid. Ovariole number is directly determined by the number of cellular structures called terminal filaments, which are stacks of cells that assemble in the larval ovary. Elucidating the developmental and regulatory mechanisms of terminal filament formation is thus key to understanding the regulation of insect reproduction through ovariole number regulation. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17275
27 Samples
Download data: TSV
Series
Accession:
GSE172015
ID:
200172015
6.

Gene expression profiling of Drosophila melanogaster larval brains after chronich alcohol exposure

(Submitter supplied) We sequenced mRNA extracted from brains of (1) D. melanogaster larvae exposed to food containing 5% ethanol (v/v) for 6 conscutive days, and (2) an age-matched untreated control larvae, that grew in regular food. Differential gene expression between the two groups was calculated and reported. Each group consisted of 3 biological replicates of 30 brains each.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19132
6 Samples
Download data: TXT
Series
Accession:
GSE185625
ID:
200185625
7.

Cut&Tag of ZGA staged embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL25244
8 Samples
Download data: BW
Series
Accession:
GSE173240
ID:
200173240
8.

Interaction of Male Specific Lethal complex and genomic imbalance on global gene expression in Drosophila

(Submitter supplied) Here, in order to investigate the regulation mechanism of the MSL complex in unbalanced genomes and its further functions involved in sexual dimorphism, we over-expressed MSL2 in autosomal aneuploidy (XX, AAA) and sex chromosome aneuploidy (XXX, AA), and analyzed the different transcriptomes.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
16 Samples
Download data: TXT
Series
Accession:
GSE162951
ID:
200162951
9.

Histone variant H2A.Z regulates zygotic genome activation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
4 related Platforms
73 Samples
Download data: BW
Series
Accession:
GSE161594
ID:
200161594
10.

RNA-seq of staged embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19132 GPL23323
11 Samples
Download data: TSV
Series
Accession:
GSE161593
ID:
200161593
11.

H2A.Z RELACS of ZGA staged embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL23323
8 Samples
Download data: BW
Series
Accession:
GSE161592
ID:
200161592
12.

MNase-seq of Ctrl and DomKD ZGA embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL25244
4 Samples
Download data: BW
Series
Accession:
GSE161591
ID:
200161591
13.

HiC of Ctrl and DomKD ZGA embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Other
Platform:
GPL22106
4 Samples
Download data: BW, H5
Series
Accession:
GSE161590
ID:
200161590
14.

Zygotic transcription of ZGA staged embryos [GRO-seq]

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Other
Platform:
GPL22106
6 Samples
Download data: BW, TSV
Series
Accession:
GSE161589
ID:
200161589
15.

ChIP-seq of ZGA staged embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19132 GPL22106 GPL25244
28 Samples
Download data: BW, TSV
Series
Accession:
GSE161588
ID:
200161588
16.

ATAC-seq of ZGA staged embryos

(Submitter supplied) During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development, still, it regulates the activation of only a small subset of genes at ZGA. However, thousands of genes do not require Zelda, suggesting that other mechanisms exist. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19132 GPL23323
4 Samples
Download data: BW
Series
Accession:
GSE161587
ID:
200161587
17.

Bulk ATAC-seq on whole brain across DGRP lines (homozigous fly lines)

(Submitter supplied) Bulk ATAC-seq performed on whole adult brains across multiple homozigous fly lines (DGRP) in order to find caQTLs. Young adults (1-3 days) were used for all genotypes.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19132 GPL21306
44 Samples
Download data: MAT
Series
Accession:
GSE181494
ID:
200181494
18.

rDNA transcription initiation complex is required for selective silencing of damaged ribosomal genes in Drosophila

(Submitter supplied) Eukaryotic genomes contain hundreds of nearly identical rRNA genes, many of which are transcriptionally silent. However, the mechanisms of selective regulation of individual rDNA units remain poorly understood. In Drosophila melanogaster, rDNA repeats containing insertions of R1/R2 retrotransposons within the 28S rRNA sequence undergo inactivation, whereas the underlying mechanism of this repression remains unknown. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL30567 GPL21306
8 Samples
Download data: CSV
Series
Accession:
GSE183035
ID:
200183035
19.

Su(H) ChIP-on-chip of Notch-stimulated overgrowing Drosophila melanogaster wing imaginal discs

(Submitter supplied) Aim: Su(H) chromatin occupancy profiling by ChIP on larval wing imaginal discs of Drosophila melanogaster to study the cooperation between Notch activation and loss of epithelial polarity (scrib mutation) during neoplastic growth. Results: The combination of Notch activation and scribble mutation (NS) does not lead to a general redeployment of Su(H) binding as compared to individual conditions (Notch only (N), and scrib mutation only (S))
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL15057
6 Samples
Download data: PAIR, SGR
Series
Accession:
GSE185490
ID:
200185490
20.

Two oppositely-chargedsf3b1 mutations cause defective development, impaired immune response, and aberrant selection of intronic branch sites in Drosophila

(Submitter supplied) Somatic SF3b1 mutations occur in many cancers, and the highly conserved H662 residue is one of the most frequently mutated sites. To address their mechanism on splicing alteration and effects on development, we constructed mutant strains at the corresponding residue H698 in Drosophila using CRISPR-Cas9 system. Two mutations, H698D and H698R, were selected due to their presence in patients and the significantly opposite charges. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23702
15 Samples
Download data: TXT
Series
Accession:
GSE171002
ID:
200171002
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=txid7227[Organism]|query=1|qty=144|blobid=MCID_617a0243dfb3cd6c6572ee2b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center