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Items: 1 to 20 of 37

1.

Parent-of-origin effects on nuclear chromatin organization and behavior in Drosophila model of Williams-Beuren Syndrome.

(Submitter supplied) Development of prognostic models for neuropsychiatric disorders requires careful consideration of individual 1) parent-of-origin effects (POEs) relying on 2) nuclear 3D chromatin architecture of the nerve cells and 3) epigenetic impact of miRNAs produced in parental germ cells. The interplay of these events in shaping cognitive phenotypes in progeny is far from clear. Simple experimental model systems such as Drosophila can help to probe the causes and consequences leading to human neuropathology. more...
Organism:
Drosophila melanogaster
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL13304
15 Samples
Download data: TXT
Series
Accession:
GSE150980
ID:
200150980
2.

RNA-seq: technical variability and sampling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Drosophila simulans
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL17484 GPL11203
12 Samples
Download data: CSV
Series
Accession:
GSE54069
ID:
200054069
3.

RNA-seq: technical variability and sampling (female)

(Submitter supplied) Background: RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, and splicing between samples as well as quantitative differences among samples are beginning to surface. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11203
6 Samples
Download data: BED, CSV
Series
Accession:
GSE54067
ID:
200054067
4.

Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains

(Submitter supplied) Drosophila melanogaster adult males perform an elaborate courtship ritual to entice females to mate. fruitless (fru), a gene that is one of the key regulators of male courtship behavior, encodes multiple male-specific isoforms (FruM). These isoforms vary in their carboxy-terminal zinc finger domains, which are predicted to facilitate DNA binding. By over-expressing individual FruM isoforms in fru-expressing neurons in either males or females and assaying the global transcriptional response by RNA-sequencing, we show that three FruM isoforms have different regulatory activities that depend on the sex of the fly. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11203
39 Samples
Download data: CSV
Series
Accession:
GSE50515
ID:
200050515
5.

The Genetic Basis of Rapidly Evolving Male Genital Morphology in Drosophila.

(Submitter supplied) We performed genome-wide expression assays comparing gene expression in the Drosophila melanogaster third larval instar genital imaginal disc between males and females. We used microarrays to compare the relative expression levels of five independent male versus female comparisons for each of two different D. melanogaster wild-type strains, Canton-S and Berlin.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL6799
10 Samples
Download data: GPR
Series
Accession:
GSE26348
ID:
200026348
6.

Whole genome microarray analysis of the Drosophila morphogenetic process

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL6799
88 Samples
Download data: GPR
Series
Accession:
GSE11316
ID:
200011316
7.

Drosophila Sex Hierarchy Regulated Gene Expression in 48 hour APF Pupae

(Submitter supplied) Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. In somatic tissues at 48 hour After Puparium Formation (APF), 173 sex-biased transcripts that likely function downstream of the doublesex (dsx) branch of the sex determination hierarchy were identified. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL6799
28 Samples
Download data: GPR
Series
Accession:
GSE11311
ID:
200011311
8.

Drosophila Sex Hierarchy Regulated Gene Expression in Adult Head and Central Nervous System Tissues

(Submitter supplied) The Drosophila sex determination hierarchy controls all aspects of somatic sexual differentiation, including sex-specific differences in adult morphology and behavior. To gain insight into the molecular-genetic specification of reproductive behaviors and physiology, we identified genes expressed in the adult head and central nervous system that are regulated downstream of sex-specific transcription factors encoded by doublesex (dsx) and fruitless (fru). more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL5983
42 Samples
Download data: GPR
Series
Accession:
GSE9185
ID:
200009185
9.

Berlin_heat_shocked_rep2

Organism:
Drosophila melanogaster
Source name:
whole fly
Platform:
GPL13304
Series:
GSE150980
Download data: TXT
Sample
Accession:
GSM4563321
ID:
304563321
10.

Berlin_heat_shocked_rep1

Organism:
Drosophila melanogaster
Source name:
whole fly
Platform:
GPL13304
Series:
GSE150980
Download data: TXT
Sample
Accession:
GSM4563320
ID:
304563320
11.

Berlin_rep2

Organism:
Drosophila melanogaster
Source name:
whole fly
Platform:
GPL13304
Series:
GSE150980
Download data: TXT
Sample
Accession:
GSM4563319
ID:
304563319
12.

Berlin_rep1

Organism:
Drosophila melanogaster
Source name:
whole fly
Platform:
GPL13304
Series:
GSE150980
Download data: TXT
Sample
Accession:
GSM4563318
ID:
304563318
13.

Dmel_F_BR4_TR2

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306665
ID:
301306665
14.

Dmel_F_BR4_TR1

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306664
ID:
301306664
15.

Dmel_F_BR3_TR2

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306663
ID:
301306663
16.

Dmel_F_BR3_TR1

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306662
ID:
301306662
17.

Dmel_F_BR2_TR2

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306661
ID:
301306661
18.

Dmel_F_BR2_TR1

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE54067 GSE54069
Download data: CSV
Sample
Accession:
GSM1306660
ID:
301306660
19.

AH_BerM_3

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE50515
Download data: CSV
Sample
Accession:
GSM1220616
ID:
301220616
20.

AH_BerM_2

Organism:
Drosophila melanogaster
Source name:
Adult Head Tissue
Platform:
GPL11203
Series:
GSE50515
Download data: CSV
Sample
Accession:
GSM1220615
ID:
301220615
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