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Items: 1 to 20 of 131

1.

Identification and characterization of centromeric sequences in Xenopus laevis

(Submitter supplied) Centromeres play an essential role in cell division by specifying the site of kinetochore formation on each chromosome so that chromosomes can attach to the mitotic spindle for segregation. Centromeres are defined epigenetically by the histone  H3 variant CEntromere Protein A (CENP-A). Dividing cells maintain the centromere  by depositing new CENP-A each cell cycle to replenish CENP-A diluted by replication. more...
Organism:
Xenopus laevis
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL22393 GPL22426
15 Samples
Download data: BED, BW, FA
Series
Accession:
GSE153058
ID:
200153058
2.

Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits

(Submitter supplied) Various species of non-coding RNAs (ncRNAs) are enriched in subcellular compartments but the mechanisms orchestrating their localization and their local functions remain largely unknown. We investigated both aspects using the elongating retinal ganglion cell axon and its tip, the growth cone, as models. We reveal that specific endogenous precursor microRNAs (pre-miRNAs) are actively trafficked to distal axons by hitchhiking primarily on late endosomes / lysosomes. more...
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21248
1 Sample
Download data: TXT
Series
Accession:
GSE124168
ID:
200124168
3.

Etv6-dependent positive and negative gene regulatory network controls vegfa expression in vivo

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21248
12 Samples
Download data
Series
Accession:
GSE115225
ID:
200115225
4.

Etv6-dependent positive and negative gene regulatory network controls vegfa expression in vivo [ChIP-seq]

(Submitter supplied) VEGFA signaling is crucial for physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent signaling pathways downstream of VegfA have been uncovered, vegfa transcriptional regulation in vivo is unclear. Here, we show that ETS transcription factor Etv6 positively regulates vegfa expression during blood stem cell development through multiple transcriptional inputs. more...
Organism:
Xenopus laevis
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21248
6 Samples
Download data: BED
Series
Accession:
GSE115224
ID:
200115224
5.

Etv6-dependent positive and negative gene regulatory network controls vegfa expression in vivo [RNA-seq]

(Submitter supplied) VEGFA signaling is crucial for physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent signaling pathways downstream of VegfA have been uncovered, vegfa transcriptional regulation in vivo is unclear. Here, we show that ETS transcription factor Etv6 positively regulates vegfa expression during blood stem cell development through multiple transcriptional inputs. more...
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21248
6 Samples
Download data
Series
Accession:
GSE115220
ID:
200115220
6.

Developmental gene expression of Xenopus laevis J strain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17682
56 Samples
Download data
Series
Accession:
GSE73431
ID:
200073431
7.

Developmental gene expression of Xenopus laevis J strain [stage]

(Submitter supplied) Comprehensive RNA-seq experiments to measure the expression of homoeologs across different developmental stages, as a part of the Xenopus laevis genome project. This work is funded by Agency Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT; "Genome Science" Grant ID 221S0002).
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17682
28 Samples
Download data: TXT
Series
Accession:
GSE73430
ID:
200073430
8.

Tissue gene expression of Xenopus laevis J strain [tissue]

(Submitter supplied) Comprehensive RNA-seq experiments to measure the expression of homoeologs across different tissues, as a part of the Xenopus laevis genome project. This work is funded by Agency Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT; "Genome Science" Grant ID 221S0002).
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17682
28 Samples
Download data: TXT
Series
Accession:
GSE73419
ID:
200073419
9.

On the relationship of protein and mRNA dynamics in vertebrate embryonic development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20998
36 Samples
Download data
Series
Accession:
GSE73905
ID:
200073905
10.

On the relationship of protein and mRNA dynamics in vertebrate embryonic development [RiboZero]

(Submitter supplied) A biochemical explanation of development from the fertilized egg to the adult anatomy requires an understanding of the complement of proteins and RNAs expressed over time during embryogenesis. Here we present a comprehensive characterization of protein and mRNA dynamics across early development in Xenopus. Surprisingly, we find that most proteins change very little and duplicated genes are expressed similarly. more...
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20998
18 Samples
Download data: FA, TSV
Series
Accession:
GSE73904
ID:
200073904
11.

On the relationship of protein and mRNA dynamics in vertebrate embryonic development [polyA]

(Submitter supplied) A biochemical explanation of development from the fertilized egg to the adult anatomy requires an understanding of the complement of proteins and RNAs expressed over time during embryogenesis. Here we present a comprehensive characterization of protein and mRNA dynamics across early development in Xenopus. Surprisingly, we find that most proteins change very little and duplicated genes are expressed similarly. more...
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20998
18 Samples
Download data: FA, TSV
Series
Accession:
GSE73870
ID:
200073870
12.

input_DNA_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633656
ID:
304633656
13.

input_DNA_rep3

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633655
ID:
304633655
14.

input_DNA_rep2

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633654
ID:
304633654
15.

input_DNA_rep1

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633653
ID:
304633653
16.

H4_ChIP_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633651
ID:
304633651
17.

H4_ChIP_rep3

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633650
ID:
304633650
18.

H4_ChIP_rep2

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633649
ID:
304633649
19.

H4_ChIP_rep1

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633648
ID:
304633648
20.

CENP-A_ChIP_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633646
ID:
304633646
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