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Release Notes For GenBank Release 142

GBREL.TXT          Genetic Sequence Data Bank
                         June 15 2004

               NCBI-GenBank Flat File Release 142.0

                    Distribution Release Notes

 35532003 loci, 40325321348 bases, from 35532003 reported sequences

 This document describes the format and content of the flat files that
comprise releases of the GenBank nucleotide sequence database. If you
have any questions or comments about GenBank or this document, please
contact NCBI via email at info@ncbi.nlm.nih.gov or:

   GenBank
   National Center for Biotechnology Information
   National Library of Medicine, 38A, 8N805
   8600 Rockville Pike
   Bethesda, MD  20894
   USA
   Phone:  (301) 496-2475
   Fax:    (301) 480-9241

==========================================================================
TABLE OF CONTENTS
==========================================================================

1. INTRODUCTION

1.1 Release 142.0
1.2 Cutoff Date
1.3 Important Changes in Release 142.0
1.4 Upcoming Changes
1.5 Request for Direct Submission of Sequence Data
1.6 Organization of This Document

2. ORGANIZATION OF DATA FILES

2.1 Overview
2.2 Files
     2.2.1 File Descriptions
     2.2.5 File Sizes
     2.2.6 Per-Division Statistics 
     2.2.7 Selected Per-Organism Statistics 
     2.2.8 Growth of GenBank

3. FILE FORMATS

3.1 File Header Information
3.2 Directory Files
     3.2.1 Short Directory File
3.3 Index Files
     3.3.1 Accession Number Index File
     3.3.2 Keyword Phrase Index File
     3.3.3 Author Name Index File
     3.3.4 Journal Citation Index File
     3.3.5 Gene Name Index
3.4 Sequence Entry Files
     3.4.1 File Organization
     3.4.2  Entry Organization
     3.4.3 Sample Sequence Data File
     3.4.4 LOCUS Format
     3.4.5 DEFINITION Format
          3.4.5.1 DEFINITION Format for NLM Entries
     3.4.6 ACCESSION Format
     3.4.7 VERSION Format
     3.4.8 KEYWORDS Format
     3.4.9 SEGMENT Format
     3.4.10 SOURCE Format
     3.4.11 REFERENCE Format
     3.4.12 FEATURES Format
          3.4.12.1 Feature Key Names
          3.4.12.2 Feature Location
          3.4.12.3  Feature Qualifiers
          3.4.12.4 Cross-Reference Information
          3.4.12.5 Feature Table Examples
     3.4.13 ORIGIN Format
     3.4.14 SEQUENCE Format

4. ALTERNATE RELEASES

5. KNOWN PROBLEMS OF THE GENBANK DATABASE

5.1 Incorrect Gene Symbols in Entries and Index

6. GENBANK ADMINISTRATION 

6.1 Registered Trademark Notice
6.2 Citing GenBank
6.3 GenBank Distribution Formats and Media
6.4 Other Methods of Accessing GenBank Data
6.5 Request for Corrections and Comments
6.6 Credits and Acknowledgments
6.7 Disclaimer

==========================================================================

1. INTRODUCTION

1.1 Release 142.0

  The National Center for Biotechnology Information (NCBI) at the National
Library of Medicine (NLM), National Institutes of Health (NIH) is responsible
for producing and distributing the GenBank Sequence Database.  NCBI handles
all GenBank direct submissions and authors are advised to use the address
below.  Submitters are encouraged to use the free Sequin software package
for sending sequence data, or the newly developed World Wide Web submission
form.  See Section 1.5 below for details.

*****************************************************************************

The address for direct submissions to GenBank is:

       GenBank Submissions
       National Center for Biotechnology Information
       Bldg 38A, Rm. 8N-803
       8600 Rockville Pike
       Bethesda, MD 20894

       E-MAIL:  gb-sub@ncbi.nlm.nih.gov

Updates and changes to existing GenBank records:

       E-MAIL:  update@ncbi.nlm.nih.gov

URL for the new GenBank submission tool - BankIt - on the World Wide Web:

       http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/

(see Section 1.5 for additional details about submitting data to GenBank.)

*****************************************************************************

  GenBank Release 142.0 is a release of sequence data by NCBI in the GenBank
flatfile format.  GenBank is a component of a tri-partite, international
collaboration of sequence databases in the U.S., Europe, and Japan.  The
collaborating databases in Europe are the European Molecular Biology Laboratory
(EMBL) at Hinxton Hall, UK, and the DNA Database of Japan (DDBJ) in Mishima,
Japan.  Patent sequences are incorporated through arrangements with the
U.S. Patent and Trademark Office, and via the collaborating international
databases from other international patent offices.  The database is converted
to various output formats, including the Flat File and Abstract Syntax Notation 1
(ASN.1) versions.  The ASN.1 and Flat File forms of the data are available at
NCBI's anonymous FTP server: ftp.ncbi.nih.gov .

1.2 Cutoff Date

  This full release, 142.0, incorporates data available to the collaborating
databases as of June 18, 2004 at approximately 1:30am EDT.  For more recent
data, users are advised to:

  o Download GenBank Incremental Update (GIU) files by anonymous FTP from NCBI:

	ftp://ftp.ncbi.nih.gov/ncbi-asn1/daily-nc (ASN.1 format)
	ftp://ftp.ncbi.nih.gov/genbank/daily-nc   (flatfile format)

    Mirrors of the GenBank FTP site at the NCBI are available from the San Diego
    Supercomputer Center and the University of Indiana:

	ftp://genbank.sdsc.edu/pub
	ftp://bio-mirror.net/biomirror/genbank/

    Some users who experience slow FTP transfers of large files might realize
    an improvement in transfer rates from these alternate sites when traffic at
    the NCBI is high.

  o Use the interactive Network-Entrez or Web-Entrez applications to query
    the 'Entrez: Nucleotides' database (see Section 6.4 of this document).

1.3 Important Changes in Release 142.0

1.3.1 One index file is unavailable for GenBank 142.0

    A software problem prevented the generation of one of the 'index'
  files which normally accompany GenBank releases: 

	gbjou.idx

  Our apologies for any inconvenience that this might cause.

1.3.2 Organizational changes

  The total number of sequence data files increased by 26 with this release:

  - the EST division is now comprised of 321 files (+16)
  - the GSS division is now comprised of 110 files (+6)
  - the PLN division is now comprised of  12 files (+1)
  - the PRI division is now comprised of  28 files (+1)
  - the ROD division is now comprised of  13 files (+1)
  - the STS division is now comprised of   5 files (+1)

1.3.3 **Sequence Length Limitation Removed As Of June 2004**

  At the May 2003 collaborative meeting among representatives of GenBank,
EMBL, and DDBJ, it was decided that the 350 kilobase limit on the sequence
length of database records should be removed as of June 2004.

  Previously, individual, complete sequences were expected to be a maximum
of 350 kbp in length. One major reason for the existence of the limit was
as an aid to users of sequence analysis software, some of which might not
be capable of processing megabase-scale sequences.

  However, very significant exceptions to the 350 kbp limit have existed
for several years; Phase 1 (unordered, unoriented) and Phase 2 (ordered,
oriented) high-throughput genomic sequences (HTGS) generated by efforts
such as the Human Genome Project; large dispersed eukaryotic genes with
an intron/exon structure that spans more than 350 kbp; and sequences
which result from assemblies of Whole Genome Shotgun (WGS) project data.

  Given these exceptions, and the technological advances which have made
large-scale sequencing practical for an increasing number of researchers,
the collaboration decided that the 350 kbp limit must be removed.

  Software developers for some of the larger commercial sequence analysis
packages were asked in May 2003 what timeframe would be appropriate for this
change. Answers ranged from "immediately", to "several months", to "one year".
So the one-year timeframe was selected, to provide ample time to implement
changes which megabase-scale sequences might require.

  As of GenBank 142.0, the length of database sequences will be limited only
by the natural structures of an organism's genome. For example, it is possible
that a single record might be used to represent all of human chromosome 1,
which is approximately 245 Mbp in length.

  Some sample records with very large sequences have been made available
so that developers can test their software with them:

	ftp://ftp.ncbi.nih.gov/genbank/LargeSeqs

  Several changes are expected after the removal of the length limit. For 
example, complete bacterial genomes (typically on the order of several
megabases) will be re-assembled into single sequence records. And the submission
process for such genomes will become much more streamlined, since database
staff will no longer have to split the genomes into pieces.

1.3.4 Rename of File 'Last.Release' and Deletion of /daily Subdirectories

The files named Last.Release, which used to be located at:

	ftp://ftp.ncbi.nih.gov/genbank/daily/Last.Release
	ftp://ftp.ncbi.nih.gov/ncbi-asn1/daily/Last.Release

contain the number of the GenBank release which is currently installed
on the NCBI FTP site. As of Release 142.0 in June 2004, these files have
been moved and renamed as:

	ftp://ftp.ncbi.nih.gov/genbank/GB_Release_Number
	ftp://ftp.ncbi.nih.gov/ncbi-asn1/GB_Release_Number

The /daily subdirectories, which had been used for cumulative update
products that are no longer supported, have been deleted.

1.3.3 GSS File Header Problem

  GSS sequences at GenBank are maintained in one of two different systems,
depending on their origin. One recent change to release processing involves
the parallelization of the dumps from those systems. Because the second dump
(for example) has no prior knowledge of exactly how many GSS files will be
dumped from the first, it doesn't know how to number it's own output files.

  There is thus a discrepancy between the filenames and file headers for
eighteen GSS flatfiles in Release 142.0. Consider the gbgss93.seq file:

GBGSS1.SEQ           Genetic Sequence Data Bank
                            June 15 2004

                NCBI-GenBank Flat File Release 142.0

                           GSS Sequences (Part 1)

   88249 loci,    65635082 bases, from    88249 reported sequences

  Here, the filename and part number in the header is "1", though the file
has been renamed as "93" based on the files dumped from the other system.

  We will work to resolve this discrepancy in future releases, but the
priority is certainly much lower than many other tasks.

1.4 Upcoming Changes

1.4.1 New qualifier : /old_locus_tag

  The /locus_tag qualifier was introduced in April 2003 to provide
a method for systematically identifying genes, coding regions and
other features which typically result from computational analysis.
This qualifier is typically used instead of /gene .

  Sometimes the /locus_tag identifier series supplied by a submitter
of sequence data undergoes a change. Because the original /locus_tag
identifiers might be referenced in journal articles, or in databases,
a method of preserving the original identifiers is needed.

  A new qualifier, /old_locus_tag , will be introduced as of October
2004 for this purpose. A formal description of the qualifier will be
made available via upcoming GenBank release notes, and via the GenBank
newsgroup.

1.4.2 New type of gap() operator

  CON-division records utilize a CONTIG line with a join() statement,
which specifies how sequences can be combined to form a much larger
object. For example:

LOCUS       AE016959            23508449 bp    DNA     linear   CON 12-JUN-2003
DEFINITION  Oryza sativa (japonica cultivar-group) chromosome 10, complete
            sequence.
ACCESSION   AE016959
[....]
CONTIG      join(AE017047.1:1..300029,AE017048.1:61..300029,
            AE017049.1:61..304564,AE017050.1:61..302504,AE017051.1:61..300029,
            AE017052.1:61..300029,AE017053.1:61..303511,AE017054.1:61..302085,
            AE017055.1:61..300029,AE017056.1:61..300029,AE017057.1:61..300029,
            AE017058.1:61..300029,AE017059.1:61..300029,AE017060.1:61..95932,
            gap(30001),AE017061.1:1..300028,AE017062.1:61..306096,
[....]

  A gap operator is legal in these join statements. 'gap()' indicates a gap
of unknown length. 'gap(N)', where 'N' is a positive integer, indicates a gap
with a physically-estimated length of 'N' bases.

  In some sequencing projects, a convention is agreed upon by which gaps
of unknown length are all represented by a uniform value, such as 100.

  To capture this usage, a new type of gap operator will be legal as of
October 2004 : 'gap(unkN)', where 'N' is a positive integer. For a gap of
length 100, utilized by convention rather than reflective of the gap's
actual size, the operator would be:

      gap(unk100)

  This new gap operator will make clear the distinction between a
gap with a physically-estimated length, and a gap with a length that
has no actual physical basis. Further details about this new operator
will be made available via these release notes and the GenBank newsgroup.

1.4.3 New /compare qualifier

  Four different features exist which can be used to annotate regions
of sequence that are either uncertain or that differ in comparison
to some other sequence:

	variation
	conflict
	misc_difference
	old_sequence

  A /citation qualifier is used to refer to a publication that details
the nature of the uncertain or differing bases. However, a publication
may not always be available (unpublished references), and simply 
referring to a publication is quite indirect.

  The new /compare qualifer will provide a method for directly 
referencing a base range on a record that exhibits a sequence
difference:

	/compare="Accession.Version:X..Y"

For example:

	/compare="M10101.1:1..5"

  A formal description of /compare will be made available via upcoming
GenBank release notes, and via the GenBank newsgroup.

1.5 Request for Direct Submission of Sequence Data

  A successful GenBank requires that sequence data enter the database as
soon as possible after publication, that the annotations be as complete as
possible, and that the sequence and annotation data be accurate. All
three of these requirements are best met if authors of sequence data
submit their data directly to GenBank in a usable form. It is especially
important that these submissions be in computer-readable form.

  GenBank must rely on direct author submission of data to ensure that
it achieves its goals of completeness, accuracy, and timeliness. To
assist researchers in entering their own sequence data, GenBank
provides a WWW submission tool called BankIt, as well as a stand-alone
software package called Sequin. BankIt and Sequin are both easy-to-use
programs that enable authors to enter a sequence, annotate it, and
submit it to GenBank.  Through the international collaboration of DNA
sequence databases, GenBank submissions are forwarded daily for inclusion
in the EMBL and DDBJ databases.

  SEQUIN.  Sequin is an interactive, graphically-oriented program based
on screen forms and controlled vocabularies that guides you through the
process of entering your sequence and providing biological and
bibliographic annotation.  Sequin is designed to simplify the sequence submission
process, and to provide increased data handling capabilities to accomodate
very long sequences, complex annotations, and robust error checking.  E-mail
the completed submission file to : gb-sub@ncbi.nlm.nih.gov

  Sequin is provided for Macintosh, PC/Windows, UNIX and VMS computers.
It is available by annonymous ftp from ftp.ncbi.nih.gov; login as
anonymous and use your e-mail address as the password. It is located in
the sequin directory. Or direct your web browser to this URL:

	ftp://ftp.ncbi.nih.gov/sequin

  BANKIT.  BankIt provides a simple forms approach for submitting your
sequence and descriptive information to GenBank.  Your submission will
be submitted directly to GenBank via the World Wide Web, and
immediately forwarded for inclusion in the EMBL and DDBJ databases.
BankIt may be used with Netscape, Internet Explorer, and other common
WWW clients. You can access BankIt from GenBank's home page:   

	http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/

  AUTHORIN.  Authorin sequence submissions are no longer accepted by
GenBank, and the Authorin application is no longer distributed by NCBI.  

  If you have questions about GenBank submissions or any of the data
submission tools, contact NCBI at: info@ncbi.nlm.nih.gov or 301-496-2475.

1.6 Organization of This Document

  The second section describes the contents of GenBank releases. The third
section illustrates the formats of the flat files.  The fourth section
describes other versions of the data, the fifth section identifies known prob-
lems, and the sixth contains administrative details.

2. ORGANIZATION OF DATA FILES

2.1 Overview

  GenBank releases consist of a set of ASCII text files, most of which
contain sequence data. A few supplemental "index" files are also supplied,
containing comprehensive lists of author names, journal citations,
gene names, and keywords, along with the accession numbers of the records
in which they can be found (see Section 3.3). The line-lengths of
these files is variable.

2.2 Files

  This GenBank flat file release consists of 634 files. The lists
that follow describe each of the files included in the distribution.
Their sizes and base pair content are also summarized.

2.2.1 File Descriptions

As outlined in Section 1.3.1, the following file is unavailable
for GenBank Release 142.0 :

  gbjou.idx 	- Index of the entries according to journal citation.

Files included in this release are:

1.  gbrel.txt	- Release notes (this document).
2.  gbsdr.txt 	- Short directory of the data bank.
3.  gbacc.idx 	- Index of the entries according to accession number.
4.  gbkey.idx 	- Index of the entries according to keyword phrase.
5.  gbaut1.idx 	- Index of the entries according to author, part 1.
6.  gbaut2.idx 	- Index of the entries according to author, part 2.
7.  gbaut3.idx 	- Index of the entries according to author, part 3.
8.  gbaut4.idx 	- Index of the entries according to author, part 4.
9.  gbaut5.idx 	- Index of the entries according to author, part 5.
10.  gbaut6.idx 	- Index of the entries according to author, part 6.
11. gbaut7.idx 	- Index of the entries according to author, part 7.
12. gbaut8.idx 	- Index of the entries according to author, part 8.
13. gbaut9.idx 	- Index of the entries according to author, part 9.
14. gbaut10.idx - Index of the entries according to author, part 10.
15. gbaut11.idx - Index of the entries according to author, part 11.
16. gbaut12.idx - Index of the entries according to author, part 12.
17. gbaut13.idx - Index of the entries according to author, part 13.
18. gbaut14.idx - Index of the entries according to author, part 14.
19. gbaut15.idx - Index of the entries according to author, part 15.
20. gbaut16.idx - Index of the entries according to author, part 16.
21. gbaut17.idx - Index of the entries according to author, part 17.
22. gbaut18.idx - Index of the entries according to author, part 18.
23. gbaut19.idx - Index of the entries according to author, part 19.
24. gbaut20.idx - Index of the entries according to author, part 20.
25. gbaut21.idx - Index of the entries according to author, part 21.
26. gbaut22.idx - Index of the entries according to author, part 22.
27. gbaut23.idx - Index of the entries according to author, part 23.
28. gbaut24.idx - Index of the entries according to author, part 24.
29. gbaut25.idx - Index of the entries according to author, part 25.
30. gbgen.idx 	- Index of the entries according to gene names.
31. gbsec.idx	- Index of the entries according to secondary accession number.
32. gbpri1.seq 	- Primate sequence entries, part 1.
33. gbpri2.seq 	- Primate sequence entries, part 2.
34. gbpri3.seq 	- Primate sequence entries, part 3.
35. gbpri4.seq 	- Primate sequence entries, part 4.
36. gbpri5.seq 	- Primate sequence entries, part 5.
37. gbpri6.seq 	- Primate sequence entries, part 6.
38. gbpri7.seq 	- Primate sequence entries, part 7.
39. gbpri8.seq 	- Primate sequence entries, part 8.
40. gbpri9.seq 	- Primate sequence entries, part 9.
41. gbpri10.seq	- Primate sequence entries, part 10.
42. gbpri11.seq	- Primate sequence entries, part 11.
43. gbpri12.seq	- Primate sequence entries, part 12.
44. gbpri13.seq	- Primate sequence entries, part 13.
45. gbpri14.seq	- Primate sequence entries, part 14.
46. gbpri15.seq	- Primate sequence entries, part 15.
47. gbpri16.seq	- Primate sequence entries, part 16.
48. gbpri17.seq	- Primate sequence entries, part 17.
49. gbpri18.seq	- Primate sequence entries, part 18.
50. gbpri19.seq	- Primate sequence entries, part 19.
51. gbpri20.seq	- Primate sequence entries, part 20.
52. gbpri21.seq	- Primate sequence entries, part 21.
53. gbpri22.seq	- Primate sequence entries, part 22.
54. gbpri23.seq	- Primate sequence entries, part 23.
55. gbpri24.seq	- Primate sequence entries, part 24.
56. gbpri25.seq	- Primate sequence entries, part 25.
57. gbpri26.seq	- Primate sequence entries, part 26.
58. gbpri27.seq	- Primate sequence entries, part 27.
59. gbpri28.seq	- Primate sequence entries, part 28.
60. gbrod1.seq 	- Rodent sequence entries, part 1.
61. gbrod2.seq 	- Rodent sequence entries, part 2.
62. gbrod3.seq 	- Rodent sequence entries, part 3.
63. gbrod4.seq 	- Rodent sequence entries, part 4.
64. gbrod5.seq 	- Rodent sequence entries, part 5.
65. gbrod6.seq 	- Rodent sequence entries, part 6.
66. gbrod7.seq 	- Rodent sequence entries, part 7.
67. gbrod8.seq 	- Rodent sequence entries, part 8.
68. gbrod9.seq 	- Rodent sequence entries, part 9.
69. gbrod10.seq - Rodent sequence entries, part 10.
70. gbrod11.seq - Rodent sequence entries, part 11.
71. gbrod12.seq - Rodent sequence entries, part 12.
72. gbrod13.seq - Rodent sequence entries, part 13.
73. gbmam.seq 	- Other mammalian sequence entries.
74. gbvrt1.seq 	- Other vertebrate sequence entries, part 1.
75. gbvrt2.seq 	- Other vertebrate sequence entries, part 2.
76. gbvrt3.seq 	- Other vertebrate sequence entries, part 3.
77. gbvrt4.seq 	- Other vertebrate sequence entries, part 4.
78. gbvrt5.seq 	- Other vertebrate sequence entries, part 5.
79. gbvrt6.seq 	- Other vertebrate sequence entries, part 5.
80. gbinv1.seq 	- Invertebrate sequence entries, part 1.
81. gbinv2.seq 	- Invertebrate sequence entries, part 2.
82. gbinv3.seq 	- Invertebrate sequence entries, part 3.
83. gbinv4.seq 	- Invertebrate sequence entries, part 4.
84. gbinv5.seq 	- Invertebrate sequence entries, part 5.
85. gbinv6.seq 	- Invertebrate sequence entries, part 6.
86. gbpln1.seq 	- Plant sequence entries (including fungi and algae), part 1.
87. gbpln2.seq 	- Plant sequence entries (including fungi and algae), part 2.
88. gbpln3.seq 	- Plant sequence entries (including fungi and algae), part 3.
89. gbpln4.seq 	- Plant sequence entries (including fungi and algae), part 4.
90. gbpln5.seq 	- Plant sequence entries (including fungi and algae), part 5.
91. gbpln6.seq 	- Plant sequence entries (including fungi and algae), part 6.
92. gbpln7.seq 	- Plant sequence entries (including fungi and algae), part 7.
93. gbpln8.seq 	- Plant sequence entries (including fungi and algae), part 8.
94. gbpln9.seq 	- Plant sequence entries (including fungi and algae), part 9.
95. gbpln10.seq - Plant sequence entries (including fungi and algae), part 10.
96. gbpln11.seq - Plant sequence entries (including fungi and algae), part 11.
97. gbpln12.seq - Plant sequence entries (including fungi and algae), part 12.
98. gbbct1.seq 	- Bacterial sequence entries, part 1.
99. gbbct2.seq 	- Bacterial sequence entries, part 2.
100. gbbct3.seq 	- Bacterial sequence entries, part 3.
101. gbbct4.seq 	- Bacterial sequence entries, part 4.
102. gbbct5.seq 	- Bacterial sequence entries, part 5.
103. gbbct6.seq 	- Bacterial sequence entries, part 6.
104. gbbct7.seq 	- Bacterial sequence entries, part 7.
105. gbbct8.seq - Bacterial sequence entries, part 8.
106. gbbct9.seq - Bacterial sequence entries, part 9.
107. gbvrl1.seq - Viral sequence entries, part 1.
108. gbvrl2.seq - Viral sequence entries, part 2.
109. gbvrl3.seq - Viral sequence entries, part 3.
110. gbvrl4.seq - Viral sequence entries, part 4.
111. gbphg.seq 	- Phage sequence entries.
112. gbsyn.seq 	- Synthetic and chimeric sequence entries.
113. gbuna.seq 	- Unannotated sequence entries.
114. gbest1.seq  - EST (expressed sequence tag) sequence entries, part 1.
115. gbest2.seq  - EST (expressed sequence tag) sequence entries, part 2.
116. gbest3.seq  - EST (expressed sequence tag) sequence entries, part 3.
117. gbest4.seq  - EST (expressed sequence tag) sequence entries, part 4.
118. gbest5.seq  - EST (expressed sequence tag) sequence entries, part 5.
119. gbest6.seq  - EST (expressed sequence tag) sequence entries, part 6.
120. gbest7.seq  - EST (expressed sequence tag) sequence entries, part 7.
121. gbest8.seq  - EST (expressed sequence tag) sequence entries, part 8.
122. gbest9.seq  - EST (expressed sequence tag) sequence entries, part 9.
123. gbest10.seq - EST (expressed sequence tag) sequence entries, part 10.
124. gbest11.seq - EST (expressed sequence tag) sequence entries, part 11.
125. gbest12.seq - EST (expressed sequence tag) sequence entries, part 12.
126. gbest13.seq - EST (expressed sequence tag) sequence entries, part 13.
127. gbest14.seq - EST (expressed sequence tag) sequence entries, part 14.
128. gbest15.seq - EST (expressed sequence tag) sequence entries, part 15.
129. gbest16.seq - EST (expressed sequence tag) sequence entries, part 16.
130. gbest17.seq - EST (expressed sequence tag) sequence entries, part 17.
131. gbest18.seq - EST (expressed sequence tag) sequence entries, part 18.
132. gbest19.seq - EST (expressed sequence tag) sequence entries, part 19.
133. gbest20.seq - EST (expressed sequence tag) sequence entries, part 20.
134. gbest21.seq - EST (expressed sequence tag) sequence entries, part 21.
135. gbest22.seq - EST (expressed sequence tag) sequence entries, part 22.
136. gbest23.seq - EST (expressed sequence tag) sequence entries, part 23.
137. gbest24.seq - EST (expressed sequence tag) sequence entries, part 24.
138. gbest25.seq - EST (expressed sequence tag) sequence entries, part 25.
139. gbest26.seq - EST (expressed sequence tag) sequence entries, part 26.
140. gbest27.seq - EST (expressed sequence tag) sequence entries, part 27.
141. gbest28.seq - EST (expressed sequence tag) sequence entries, part 28.
142. gbest29.seq - EST (expressed sequence tag) sequence entries, part 29.
143. gbest30.seq - EST (expressed sequence tag) sequence entries, part 30.
144. gbest31.seq - EST (expressed sequence tag) sequence entries, part 31.
145. gbest32.seq - EST (expressed sequence tag) sequence entries, part 32.
146. gbest33.seq - EST (expressed sequence tag) sequence entries, part 33.
147. gbest34.seq - EST (expressed sequence tag) sequence entries, part 34.
148. gbest35.seq - EST (expressed sequence tag) sequence entries, part 35.
149. gbest36.seq - EST (expressed sequence tag) sequence entries, part 36.
150. gbest37.seq - EST (expressed sequence tag) sequence entries, part 37.
151. gbest38.seq - EST (expressed sequence tag) sequence entries, part 38.
152. gbest39.seq - EST (expressed sequence tag) sequence entries, part 39.
153. gbest40.seq - EST (expressed sequence tag) sequence entries, part 40.
154. gbest41.seq - EST (expressed sequence tag) sequence entries, part 41.
155. gbest42.seq - EST (expressed sequence tag) sequence entries, part 42.
156. gbest43.seq - EST (expressed sequence tag) sequence entries, part 43.
157. gbest44.seq - EST (expressed sequence tag) sequence entries, part 44.
158. gbest45.seq - EST (expressed sequence tag) sequence entries, part 45.
159. gbest46.seq - EST (expressed sequence tag) sequence entries, part 46.
160. gbest47.seq - EST (expressed sequence tag) sequence entries, part 47.
161. gbest48.seq - EST (expressed sequence tag) sequence entries, part 48.
162. gbest49.seq - EST (expressed sequence tag) sequence entries, part 49.
163. gbest50.seq - EST (expressed sequence tag) sequence entries, part 50.
164. gbest51.seq - EST (expressed sequence tag) sequence entries, part 51.
165. gbest52.seq - EST (expressed sequence tag) sequence entries, part 52.
166. gbest53.seq - EST (expressed sequence tag) sequence entries, part 53.
167. gbest54.seq - EST (expressed sequence tag) sequence entries, part 54.
168. gbest55.seq - EST (expressed sequence tag) sequence entries, part 55.
169. gbest56.seq - EST (expressed sequence tag) sequence entries, part 56.
170. gbest57.seq - EST (expressed sequence tag) sequence entries, part 57.
171. gbest58.seq - EST (expressed sequence tag) sequence entries, part 58.
172. gbest59.seq - EST (expressed sequence tag) sequence entries, part 59.
173. gbest60.seq - EST (expressed sequence tag) sequence entries, part 60.
174. gbest61.seq - EST (expressed sequence tag) sequence entries, part 61.
175. gbest62.seq - EST (expressed sequence tag) sequence entries, part 62.
176. gbest63.seq - EST (expressed sequence tag) sequence entries, part 63.
177. gbest64.seq - EST (expressed sequence tag) sequence entries, part 64.
178. gbest65.seq - EST (expressed sequence tag) sequence entries, part 65.
179. gbest66.seq - EST (expressed sequence tag) sequence entries, part 66.
180. gbest67.seq - EST (expressed sequence tag) sequence entries, part 67.
181. gbest68.seq - EST (expressed sequence tag) sequence entries, part 68.
182. gbest69.seq - EST (expressed sequence tag) sequence entries, part 69.
183. gbest70.seq - EST (expressed sequence tag) sequence entries, part 70.
184. gbest71.seq - EST (expressed sequence tag) sequence entries, part 71.
185. gbest72.seq - EST (expressed sequence tag) sequence entries, part 72.
186. gbest73.seq - EST (expressed sequence tag) sequence entries, part 73.
187. gbest74.seq - EST (expressed sequence tag) sequence entries, part 74.
188. gbest75.seq - EST (expressed sequence tag) sequence entries, part 75.
189. gbest76.seq - EST (expressed sequence tag) sequence entries, part 76.
190. gbest77.seq - EST (expressed sequence tag) sequence entries, part 77.
191. gbest78.seq - EST (expressed sequence tag) sequence entries, part 78.
192. gbest79.seq - EST (expressed sequence tag) sequence entries, part 79.
193. gbest80.seq - EST (expressed sequence tag) sequence entries, part 80.
194. gbest81.seq - EST (expressed sequence tag) sequence entries, part 81.
195. gbest82.seq - EST (expressed sequence tag) sequence entries, part 82.
196. gbest83.seq - EST (expressed sequence tag) sequence entries, part 83.
197. gbest84.seq - EST (expressed sequence tag) sequence entries, part 84.
198. gbest85.seq - EST (expressed sequence tag) sequence entries, part 85.
199. gbest86.seq - EST (expressed sequence tag) sequence entries, part 86.
200. gbest87.seq - EST (expressed sequence tag) sequence entries, part 87.
201. gbest88.seq - EST (expressed sequence tag) sequence entries, part 88.
202. gbest89.seq - EST (expressed sequence tag) sequence entries, part 89
203. gbest90.seq - EST (expressed sequence tag) sequence entries, part 90.
204. gbest91.seq - EST (expressed sequence tag) sequence entries, part 91.
205. gbest92.seq - EST (expressed sequence tag) sequence entries, part 92.
206. gbest93.seq - EST (expressed sequence tag) sequence entries, part 93.
207. gbest94.seq - EST (expressed sequence tag) sequence entries, part 94.
208. gbest95.seq - EST (expressed sequence tag) sequence entries, part 95.
209. gbest96.seq - EST (expressed sequence tag) sequence entries, part 96.
210. gbest97.seq - EST (expressed sequence tag) sequence entries, part 97.
211. gbest98.seq - EST (expressed sequence tag) sequence entries, part 98.
212. gbest99.seq - EST (expressed sequence tag) sequence entries, part 99.
213. gbest100.seq - EST (expressed sequence tag) sequence entries, part 100.
214. gbest101.seq - EST (expressed sequence tag) sequence entries, part 101.
215. gbest102.seq - EST (expressed sequence tag) sequence entries, part 102.
216. gbest103.seq - EST (expressed sequence tag) sequence entries, part 103.
217. gbest104.seq - EST (expressed sequence tag) sequence entries, part 104.
218. gbest105.seq - EST (expressed sequence tag) sequence entries, part 105.
219. gbest106.seq - EST (expressed sequence tag) sequence entries, part 106.
220. gbest107.seq - EST (expressed sequence tag) sequence entries, part 107.
221. gbest108.seq - EST (expressed sequence tag) sequence entries, part 108.
222. gbest109.seq - EST (expressed sequence tag) sequence entries, part 109.
223. gbest110.seq - EST (expressed sequence tag) sequence entries, part 110.
224. gbest111.seq - EST (expressed sequence tag) sequence entries, part 111.
225. gbest112.seq - EST (expressed sequence tag) sequence entries, part 112.
226. gbest113.seq - EST (expressed sequence tag) sequence entries, part 113.
227. gbest114.seq - EST (expressed sequence tag) sequence entries, part 114.
228. gbest115.seq - EST (expressed sequence tag) sequence entries, part 115.
229. gbest116.seq - EST (expressed sequence tag) sequence entries, part 116.
230. gbest117.seq - EST (expressed sequence tag) sequence entries, part 117.
231. gbest118.seq - EST (expressed sequence tag) sequence entries, part 118.
232. gbest119.seq - EST (expressed sequence tag) sequence entries, part 119.
233. gbest120.seq - EST (expressed sequence tag) sequence entries, part 120.
234. gbest121.seq - EST (expressed sequence tag) sequence entries, part 121.
235. gbest122.seq - EST (expressed sequence tag) sequence entries, part 122.
236. gbest123.seq - EST (expressed sequence tag) sequence entries, part 123.
237. gbest124.seq - EST (expressed sequence tag) sequence entries, part 124.
238. gbest125.seq - EST (expressed sequence tag) sequence entries, part 125.
239. gbest126.seq - EST (expressed sequence tag) sequence entries, part 126.
240. gbest127.seq - EST (expressed sequence tag) sequence entries, part 127.
241. gbest128.seq - EST (expressed sequence tag) sequence entries, part 128.
242. gbest129.seq - EST (expressed sequence tag) sequence entries, part 129.
243. gbest130.seq - EST (expressed sequence tag) sequence entries, part 130.
244. gbest131.seq - EST (expressed sequence tag) sequence entries, part 131.
245. gbest132.seq - EST (expressed sequence tag) sequence entries, part 132.
246. gbest133.seq - EST (expressed sequence tag) sequence entries, part 133.
247. gbest134.seq - EST (expressed sequence tag) sequence entries, part 134.
248. gbest135.seq - EST (expressed sequence tag) sequence entries, part 135.
249. gbest136.seq - EST (expressed sequence tag) sequence entries, part 136.
250. gbest137.seq - EST (expressed sequence tag) sequence entries, part 137.
251. gbest138.seq - EST (expressed sequence tag) sequence entries, part 138.
252. gbest139.seq - EST (expressed sequence tag) sequence entries, part 139.
253. gbest140.seq - EST (expressed sequence tag) sequence entries, part 140.
254. gbest141.seq - EST (expressed sequence tag) sequence entries, part 141.
255. gbest142.seq - EST (expressed sequence tag) sequence entries, part 142.
256. gbest143.seq - EST (expressed sequence tag) sequence entries, part 143.
257. gbest144.seq - EST (expressed sequence tag) sequence entries, part 144.
258. gbest145.seq - EST (expressed sequence tag) sequence entries, part 145.
259. gbest146.seq - EST (expressed sequence tag) sequence entries, part 146.
260. gbest147.seq - EST (expressed sequence tag) sequence entries, part 147.
261. gbest148.seq - EST (expressed sequence tag) sequence entries, part 148.
262. gbest149.seq - EST (expressed sequence tag) sequence entries, part 149.
263. gbest150.seq - EST (expressed sequence tag) sequence entries, part 150.
264. gbest151.seq - EST (expressed sequence tag) sequence entries, part 151.
265. gbest152.seq - EST (expressed sequence tag) sequence entries, part 152.
266. gbest153.seq - EST (expressed sequence tag) sequence entries, part 153.
267. gbest154.seq - EST (expressed sequence tag) sequence entries, part 154.
268. gbest155.seq - EST (expressed sequence tag) sequence entries, part 155.
269. gbest156.seq - EST (expressed sequence tag) sequence entries, part 156.
270. gbest157.seq - EST (expressed sequence tag) sequence entries, part 157.
271. gbest158.seq - EST (expressed sequence tag) sequence entries, part 158.
272. gbest159.seq - EST (expressed sequence tag) sequence entries, part 159.
273. gbest160.seq - EST (expressed sequence tag) sequence entries, part 160.
274. gbest161.seq - EST (expressed sequence tag) sequence entries, part 161.
275. gbest162.seq - EST (expressed sequence tag) sequence entries, part 162.
276. gbest163.seq - EST (expressed sequence tag) sequence entries, part 163.
277. gbest164.seq - EST (expressed sequence tag) sequence entries, part 164.
278. gbest165.seq - EST (expressed sequence tag) sequence entries, part 165.
279. gbest166.seq - EST (expressed sequence tag) sequence entries, part 166.
280. gbest167.seq - EST (expressed sequence tag) sequence entries, part 167.
281. gbest168.seq - EST (expressed sequence tag) sequence entries, part 168.
282. gbest169.seq - EST (expressed sequence tag) sequence entries, part 169.
283. gbest170.seq - EST (expressed sequence tag) sequence entries, part 170.
284. gbest171.seq - EST (expressed sequence tag) sequence entries, part 171.
285. gbest172.seq - EST (expressed sequence tag) sequence entries, part 172.
286. gbest173.seq - EST (expressed sequence tag) sequence entries, part 173.
287. gbest174.seq - EST (expressed sequence tag) sequence entries, part 174.
288. gbest175.seq - EST (expressed sequence tag) sequence entries, part 175.
289. gbest176.seq - EST (expressed sequence tag) sequence entries, part 176.
290. gbest177.seq - EST (expressed sequence tag) sequence entries, part 177.
291. gbest178.seq - EST (expressed sequence tag) sequence entries, part 178.
292. gbest179.seq - EST (expressed sequence tag) sequence entries, part 179.
293. gbest180.seq - EST (expressed sequence tag) sequence entries, part 180.
294. gbest181.seq - EST (expressed sequence tag) sequence entries, part 181.
295. gbest182.seq - EST (expressed sequence tag) sequence entries, part 182.
296. gbest183.seq - EST (expressed sequence tag) sequence entries, part 183.
297. gbest184.seq - EST (expressed sequence tag) sequence entries, part 184.
298. gbest185.seq - EST (expressed sequence tag) sequence entries, part 185.
299. gbest186.seq - EST (expressed sequence tag) sequence entries, part 186.
300. gbest187.seq - EST (expressed sequence tag) sequence entries, part 187.
301. gbest188.seq - EST (expressed sequence tag) sequence entries, part 188.
302. gbest189.seq - EST (expressed sequence tag) sequence entries, part 189.
303. gbest190.seq - EST (expressed sequence tag) sequence entries, part 190.
304. gbest191.seq - EST (expressed sequence tag) sequence entries, part 191.
305. gbest192.seq - EST (expressed sequence tag) sequence entries, part 192.
306. gbest193.seq - EST (expressed sequence tag) sequence entries, part 193.
307. gbest194.seq - EST (expressed sequence tag) sequence entries, part 194.
308. gbest195.seq - EST (expressed sequence tag) sequence entries, part 195.
309. gbest196.seq - EST (expressed sequence tag) sequence entries, part 196.
310. gbest197.seq - EST (expressed sequence tag) sequence entries, part 197.
311. gbest198.seq - EST (expressed sequence tag) sequence entries, part 198.
312. gbest199.seq - EST (expressed sequence tag) sequence entries, part 199.
313. gbest200.seq - EST (expressed sequence tag) sequence entries, part 200.
314. gbest201.seq - EST (expressed sequence tag) sequence entries, part 201.
315. gbest202.seq - EST (expressed sequence tag) sequence entries, part 202.
316. gbest203.seq - EST (expressed sequence tag) sequence entries, part 203.
317. gbest204.seq - EST (expressed sequence tag) sequence entries, part 204.
318. gbest205.seq - EST (expressed sequence tag) sequence entries, part 205.
319. gbest206.seq - EST (expressed sequence tag) sequence entries, part 206.
320. gbest207.seq - EST (expressed sequence tag) sequence entries, part 207.
321. gbest208.seq - EST (expressed sequence tag) sequence entries, part 208.
322. gbest209.seq - EST (expressed sequence tag) sequence entries, part 209.
323. gbest210.seq - EST (expressed sequence tag) sequence entries, part 210.
324. gbest211.seq - EST (expressed sequence tag) sequence entries, part 211.
325. gbest212.seq - EST (expressed sequence tag) sequence entries, part 212.
326. gbest213.seq - EST (expressed sequence tag) sequence entries, part 213.
327. gbest214.seq - EST (expressed sequence tag) sequence entries, part 214.
328. gbest215.seq - EST (expressed sequence tag) sequence entries, part 215.
329. gbest216.seq - EST (expressed sequence tag) sequence entries, part 216.
330. gbest217.seq - EST (expressed sequence tag) sequence entries, part 217.
331. gbest218.seq - EST (expressed sequence tag) sequence entries, part 218.
332. gbest219.seq - EST (expressed sequence tag) sequence entries, part 219.
333. gbest220.seq - EST (expressed sequence tag) sequence entries, part 220.
334. gbest221.seq - EST (expressed sequence tag) sequence entries, part 221.
335. gbest222.seq - EST (expressed sequence tag) sequence entries, part 222.
336. gbest223.seq - EST (expressed sequence tag) sequence entries, part 223.
337. gbest224.seq - EST (expressed sequence tag) sequence entries, part 224.
338. gbest225.seq - EST (expressed sequence tag) sequence entries, part 225.
339. gbest226.seq - EST (expressed sequence tag) sequence entries, part 226.
340. gbest227.seq - EST (expressed sequence tag) sequence entries, part 227.
341. gbest228.seq - EST (expressed sequence tag) sequence entries, part 228.
342. gbest229.seq - EST (expressed sequence tag) sequence entries, part 229.
343. gbest230.seq - EST (expressed sequence tag) sequence entries, part 230.
344. gbest231.seq - EST (expressed sequence tag) sequence entries, part 231.
345. gbest232.seq - EST (expressed sequence tag) sequence entries, part 232.
346. gbest233.seq - EST (expressed sequence tag) sequence entries, part 233.
347. gbest234.seq - EST (expressed sequence tag) sequence entries, part 234.
348. gbest235.seq - EST (expressed sequence tag) sequence entries, part 235.
349. gbest236.seq - EST (expressed sequence tag) sequence entries, part 236.
350. gbest237.seq - EST (expressed sequence tag) sequence entries, part 237.
351. gbest238.seq - EST (expressed sequence tag) sequence entries, part 238.
352. gbest239.seq - EST (expressed sequence tag) sequence entries, part 239.
353. gbest240.seq - EST (expressed sequence tag) sequence entries, part 240.
354. gbest241.seq - EST (expressed sequence tag) sequence entries, part 241.
355. gbest242.seq - EST (expressed sequence tag) sequence entries, part 242.
356. gbest243.seq - EST (expressed sequence tag) sequence entries, part 243.
357. gbest244.seq - EST (expressed sequence tag) sequence entries, part 244.
358. gbest245.seq - EST (expressed sequence tag) sequence entries, part 245.
359. gbest246.seq - EST (expressed sequence tag) sequence entries, part 246.
360. gbest247.seq - EST (expressed sequence tag) sequence entries, part 247.
361. gbest248.seq - EST (expressed sequence tag) sequence entries, part 248.
362. gbest249.seq - EST (expressed sequence tag) sequence entries, part 249.
363. gbest250.seq - EST (expressed sequence tag) sequence entries, part 250.
364. gbest251.seq - EST (expressed sequence tag) sequence entries, part 251.
365. gbest252.seq - EST (expressed sequence tag) sequence entries, part 252.
366. gbest253.seq - EST (expressed sequence tag) sequence entries, part 253.
367. gbest254.seq - EST (expressed sequence tag) sequence entries, part 254.
368. gbest255.seq - EST (expressed sequence tag) sequence entries, part 255.
369. gbest256.seq - EST (expressed sequence tag) sequence entries, part 256.
370. gbest257.seq - EST (expressed sequence tag) sequence entries, part 257.
371. gbest258.seq - EST (expressed sequence tag) sequence entries, part 258.
372. gbest259.seq - EST (expressed sequence tag) sequence entries, part 259.
373. gbest260.seq - EST (expressed sequence tag) sequence entries, part 260.
374. gbest261.seq - EST (expressed sequence tag) sequence entries, part 261.
375. gbest262.seq - EST (expressed sequence tag) sequence entries, part 262.
376. gbest263.seq - EST (expressed sequence tag) sequence entries, part 263.
377. gbest264.seq - EST (expressed sequence tag) sequence entries, part 264.
378. gbest265.seq - EST (expressed sequence tag) sequence entries, part 265.
379. gbest266.seq - EST (expressed sequence tag) sequence entries, part 266.
380. gbest267.seq - EST (expressed sequence tag) sequence entries, part 267.
381. gbest268.seq - EST (expressed sequence tag) sequence entries, part 268.
382. gbest269.seq - EST (expressed sequence tag) sequence entries, part 269.
383. gbest270.seq - EST (expressed sequence tag) sequence entries, part 270.
384. gbest271.seq - EST (expressed sequence tag) sequence entries, part 271.
385. gbest272.seq - EST (expressed sequence tag) sequence entries, part 272.
386. gbest273.seq - EST (expressed sequence tag) sequence entries, part 273.
387. gbest274.seq - EST (expressed sequence tag) sequence entries, part 274.
388. gbest275.seq - EST (expressed sequence tag) sequence entries, part 275.
389. gbest276.seq - EST (expressed sequence tag) sequence entries, part 276.
390. gbest277.seq - EST (expressed sequence tag) sequence entries, part 277.
391. gbest278.seq - EST (expressed sequence tag) sequence entries, part 278.
392. gbest279.seq - EST (expressed sequence tag) sequence entries, part 279.
393. gbest280.seq - EST (expressed sequence tag) sequence entries, part 280.
394. gbest281.seq - EST (expressed sequence tag) sequence entries, part 281.
395. gbest282.seq - EST (expressed sequence tag) sequence entries, part 282.
396. gbest283.seq - EST (expressed sequence tag) sequence entries, part 283.
397. gbest284.seq - EST (expressed sequence tag) sequence entries, part 284.
398. gbest285.seq - EST (expressed sequence tag) sequence entries, part 285.
399. gbest286.seq - EST (expressed sequence tag) sequence entries, part 286.
400. gbest287.seq - EST (expressed sequence tag) sequence entries, part 287.
401. gbest288.seq - EST (expressed sequence tag) sequence entries, part 288.
402. gbest289.seq - EST (expressed sequence tag) sequence entries, part 289.
403. gbest290.seq - EST (expressed sequence tag) sequence entries, part 290.
404. gbest291.seq - EST (expressed sequence tag) sequence entries, part 291.
405. gbest292.seq - EST (expressed sequence tag) sequence entries, part 292.
406. gbest293.seq - EST (expressed sequence tag) sequence entries, part 293.
407. gbest294.seq - EST (expressed sequence tag) sequence entries, part 294.
408. gbest295.seq - EST (expressed sequence tag) sequence entries, part 295.
409. gbest296.seq - EST (expressed sequence tag) sequence entries, part 296.
410. gbest297.seq - EST (expressed sequence tag) sequence entries, part 297.
411. gbest298.seq - EST (expressed sequence tag) sequence entries, part 298.
412. gbest299.seq - EST (expressed sequence tag) sequence entries, part 299.
413. gbest300.seq - EST (expressed sequence tag) sequence entries, part 300.
414. gbest301.seq - EST (expressed sequence tag) sequence entries, part 301.
415. gbest302.seq - EST (expressed sequence tag) sequence entries, part 302.
416. gbest303.seq - EST (expressed sequence tag) sequence entries, part 303.
417. gbest304.seq - EST (expressed sequence tag) sequence entries, part 304.
418. gbest305.seq - EST (expressed sequence tag) sequence entries, part 305.
419. gbest306.seq - EST (expressed sequence tag) sequence entries, part 306.
420. gbest307.seq - EST (expressed sequence tag) sequence entries, part 307.
421. gbest308.seq - EST (expressed sequence tag) sequence entries, part 308.
422. gbest309.seq - EST (expressed sequence tag) sequence entries, part 309.
423. gbest310.seq - EST (expressed sequence tag) sequence entries, part 310.
424. gbest311.seq - EST (expressed sequence tag) sequence entries, part 311.
425. gbest312.seq - EST (expressed sequence tag) sequence entries, part 312.
426. gbest313.seq - EST (expressed sequence tag) sequence entries, part 313.
427. gbest314.seq - EST (expressed sequence tag) sequence entries, part 314.
428. gbest315.seq - EST (expressed sequence tag) sequence entries, part 315.
429. gbest316.seq - EST (expressed sequence tag) sequence entries, part 316.
430. gbest317.seq - EST (expressed sequence tag) sequence entries, part 317.
431. gbest318.seq - EST (expressed sequence tag) sequence entries, part 318.
432. gbest319.seq - EST (expressed sequence tag) sequence entries, part 319.
433. gbest320.seq - EST (expressed sequence tag) sequence entries, part 320.
434. gbest321.seq - EST (expressed sequence tag) sequence entries, part 321.
435. gbpat1.seq  - Patent sequence entries, part 1.
436. gbpat2.seq  - Patent sequence entries, part 2.
437. gbpat3.seq  - Patent sequence entries, part 3.
438. gbpat4.seq  - Patent sequence entries, part 4.
439. gbpat5.seq  - Patent sequence entries, part 5.
440. gbpat6.seq  - Patent sequence entries, part 6.
441. gbpat7.seq  - Patent sequence entries, part 7.
442. gbpat8.seq  - Patent sequence entries, part 8.
443. gbpat9.seq  - Patent sequence entries, part 9.
444. gbpat10.seq - Patent sequence entries, part 10.
445. gbpat11.seq - Patent sequence entries, part 11.
446. gbpat12.seq - Patent sequence entries, part 12.
447. gbpat13.seq - Patent sequence entries, part 13.
448. gbpat14.seq - Patent sequence entries, part 14.
449. gbpat15.seq - Patent sequence entries, part 15.
450. gbsts1.seq  - STS (sequence tagged site) sequence entries, part 1.
451. gbsts2.seq  - STS (sequence tagged site) sequence entries, part 2.
452. gbsts3.seq  - STS (sequence tagged site) sequence entries, part 3.
453. gbsts4.seq  - STS (sequence tagged site) sequence entries, part 4.
454. gbsts5.seq  - STS (sequence tagged site) sequence entries, part 5.
455. gbgss1.seq  - GSS (genome survey sequence) sequence entries, part 1.
456. gbgss2.seq  - GSS (genome survey sequence) sequence entries, part 2.
457. gbgss3.seq  - GSS (genome survey sequence) sequence entries, part 3.
458. gbgss4.seq  - GSS (genome survey sequence) sequence entries, part 4.
459. gbgss5.seq  - GSS (genome survey sequence) sequence entries, part 5.
460. gbgss6.seq  - GSS (genome survey sequence) sequence entries, part 6.
461. gbgss7.seq  - GSS (genome survey sequence) sequence entries, part 7.
462. gbgss8.seq  - GSS (genome survey sequence) sequence entries, part 8.
463. gbgss9.seq  - GSS (genome survey sequence) sequence entries, part 9.
464. gbgss10.seq - GSS (genome survey sequence) sequence entries, part 10.
465. gbgss11.seq - GSS (genome survey sequence) sequence entries, part 11.
466. gbgss12.seq - GSS (genome survey sequence) sequence entries, part 12.
467. gbgss13.seq - GSS (genome survey sequence) sequence entries, part 13.
468. gbgss14.seq - GSS (genome survey sequence) sequence entries, part 14.
469. gbgss15.seq - GSS (genome survey sequence) sequence entries, part 15.
470. gbgss16.seq - GSS (genome survey sequence) sequence entries, part 16.
471. gbgss17.seq - GSS (genome survey sequence) sequence entries, part 17.
472. gbgss18.seq - GSS (genome survey sequence) sequence entries, part 18.
473. gbgss19.seq - GSS (genome survey sequence) sequence entries, part 19.
474. gbgss20.seq - GSS (genome survey sequence) sequence entries, part 20.
475. gbgss21.seq - GSS (genome survey sequence) sequence entries, part 21.
476. gbgss22.seq - GSS (genome survey sequence) sequence entries, part 22.
477. gbgss23.seq - GSS (genome survey sequence) sequence entries, part 23.
478. gbgss24.seq - GSS (genome survey sequence) sequence entries, part 24.
479. gbgss25.seq - GSS (genome survey sequence) sequence entries, part 25.
480. gbgss26.seq - GSS (genome survey sequence) sequence entries, part 26.
481. gbgss27.seq - GSS (genome survey sequence) sequence entries, part 27.
482. gbgss28.seq - GSS (genome survey sequence) sequence entries, part 28.
483. gbgss29.seq - GSS (genome survey sequence) sequence entries, part 29.
484. gbgss30.seq - GSS (genome survey sequence) sequence entries, part 30.
485. gbgss31.seq - GSS (genome survey sequence) sequence entries, part 31.
486. gbgss32.seq - GSS (genome survey sequence) sequence entries, part 32.
487. gbgss33.seq - GSS (genome survey sequence) sequence entries, part 33.
488. gbgss34.seq - GSS (genome survey sequence) sequence entries, part 34.
489. gbgss35.seq - GSS (genome survey sequence) sequence entries, part 35.
490. gbgss36.seq - GSS (genome survey sequence) sequence entries, part 36.
491. gbgss37.seq - GSS (genome survey sequence) sequence entries, part 37.
492. gbgss38.seq - GSS (genome survey sequence) sequence entries, part 38.
493. gbgss39.seq - GSS (genome survey sequence) sequence entries, part 39.
494. gbgss40.seq - GSS (genome survey sequence) sequence entries, part 40.
495. gbgss41.seq - GSS (genome survey sequence) sequence entries, part 41.
496. gbgss42.seq - GSS (genome survey sequence) sequence entries, part 42.
497. gbgss43.seq - GSS (genome survey sequence) sequence entries, part 43.
498. gbgss44.seq - GSS (genome survey sequence) sequence entries, part 44.
499. gbgss45.seq - GSS (genome survey sequence) sequence entries, part 45.
500. gbgss46.seq - GSS (genome survey sequence) sequence entries, part 46.
501. gbgss47.seq - GSS (genome survey sequence) sequence entries, part 47.
502. gbgss48.seq - GSS (genome survey sequence) sequence entries, part 48.
503. gbgss49.seq - GSS (genome survey sequence) sequence entries, part 49.
504. gbgss50.seq - GSS (genome survey sequence) sequence entries, part 50.
505. gbgss51.seq - GSS (genome survey sequence) sequence entries, part 51.
506. gbgss52.seq - GSS (genome survey sequence) sequence entries, part 52.
507. gbgss53.seq - GSS (genome survey sequence) sequence entries, part 53.
508. gbgss54.seq - GSS (genome survey sequence) sequence entries, part 54.
509. gbgss55.seq - GSS (genome survey sequence) sequence entries, part 55.
510. gbgss56.seq - GSS (genome survey sequence) sequence entries, part 56.
511. gbgss57.seq - GSS (genome survey sequence) sequence entries, part 57.
512. gbgss58.seq - GSS (genome survey sequence) sequence entries, part 58.
513. gbgss59.seq - GSS (genome survey sequence) sequence entries, part 59.
514. gbgss60.seq - GSS (genome survey sequence) sequence entries, part 60.
515. gbgss61.seq - GSS (genome survey sequence) sequence entries, part 61.
516. gbgss62.seq - GSS (genome survey sequence) sequence entries, part 62.
517. gbgss63.seq - GSS (genome survey sequence) sequence entries, part 63.
518. gbgss64.seq - GSS (genome survey sequence) sequence entries, part 64.
519. gbgss65.seq - GSS (genome survey sequence) sequence entries, part 65.
520. gbgss66.seq - GSS (genome survey sequence) sequence entries, part 66.
521. gbgss67.seq - GSS (genome survey sequence) sequence entries, part 67.
522. gbgss68.seq - GSS (genome survey sequence) sequence entries, part 68.
523. gbgss69.seq - GSS (genome survey sequence) sequence entries, part 69.
524. gbgss70.seq - GSS (genome survey sequence) sequence entries, part 70.
525. gbgss71.seq - GSS (genome survey sequence) sequence entries, part 71.
526. gbgss72.seq - GSS (genome survey sequence) sequence entries, part 72.
527. gbgss73.seq - GSS (genome survey sequence) sequence entries, part 73.
528. gbgss74.seq - GSS (genome survey sequence) sequence entries, part 74.
529. gbgss75.seq - GSS (genome survey sequence) sequence entries, part 75.
530. gbgss76.seq - GSS (genome survey sequence) sequence entries, part 76.
531. gbgss77.seq - GSS (genome survey sequence) sequence entries, part 77.
532. gbgss78.seq - GSS (genome survey sequence) sequence entries, part 78.
533. gbgss79.seq - GSS (genome survey sequence) sequence entries, part 79.
534. gbgss80.seq - GSS (genome survey sequence) sequence entries, part 80.
535. gbgss81.seq - GSS (genome survey sequence) sequence entries, part 81.
536. gbgss82.seq - GSS (genome survey sequence) sequence entries, part 82.
537. gbgss83.seq - GSS (genome survey sequence) sequence entries, part 83.
538. gbgss84.seq - GSS (genome survey sequence) sequence entries, part 84.
539. gbgss85.seq - GSS (genome survey sequence) sequence entries, part 85.
540. gbgss86.seq - GSS (genome survey sequence) sequence entries, part 86.
541. gbgss87.seq - GSS (genome survey sequence) sequence entries, part 87.
542. gbgss88.seq - GSS (genome survey sequence) sequence entries, part 88.
543. gbgss89.seq - GSS (genome survey sequence) sequence entries, part 89.
544. gbgss90.seq - GSS (genome survey sequence) sequence entries, part 90.
545. gbgss91.seq - GSS (genome survey sequence) sequence entries, part 91.
546. gbgss92.seq - GSS (genome survey sequence) sequence entries, part 92.
547. gbgss93.seq - GSS (genome survey sequence) sequence entries, part 93.
548. gbgss94.seq - GSS (genome survey sequence) sequence entries, part 94.
549. gbgss95.seq - GSS (genome survey sequence) sequence entries, part 95.
550. gbgss96.seq - GSS (genome survey sequence) sequence entries, part 96.
551. gbgss97.seq - GSS (genome survey sequence) sequence entries, part 97.
552. gbgss98.seq - GSS (genome survey sequence) sequence entries, part 98.
553. gbgss99.seq - GSS (genome survey sequence) sequence entries, part 99.
554. gbgss100.seq - GSS (genome survey sequence) sequence entries, part 100.
555. gbgss101.seq - GSS (genome survey sequence) sequence entries, part 101.
556. gbgss102.seq - GSS (genome survey sequence) sequence entries, part 102.
557. gbgss103.seq - GSS (genome survey sequence) sequence entries, part 103.
558. gbgss104.seq - GSS (genome survey sequence) sequence entries, part 104.
559. gbgss105.seq - GSS (genome survey sequence) sequence entries, part 105.
560. gbgss106.seq - GSS (genome survey sequence) sequence entries, part 106.
561. gbgss107.seq - GSS (genome survey sequence) sequence entries, part 107.
562. gbgss108.seq - GSS (genome survey sequence) sequence entries, part 108.
563. gbgss109.seq - GSS (genome survey sequence) sequence entries, part 109.
564. gbgss110.seq - GSS (genome survey sequence) sequence entries, part 110.
565. gbhtg1.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 1.
566. gbhtg2.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 2.
567. gbhtg3.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 3.
568. gbhtg4.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 4.
569. gbhtg5.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 5.
570. gbhtg6.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 6.
571. gbhtg7.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 7.
572. gbhtg8.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 8.
573. gbhtg9.seq  - HTGS (high throughput genomic sequencing) sequence entries, part 9.
574. gbhtg10.seq - HTGS (high throughput genomic sequencing) sequence entries, part 10.
575. gbhtg11.seq - HTGS (high throughput genomic sequencing) sequence entries, part 11.
576. gbhtg12.seq - HTGS (high throughput genomic sequencing) sequence entries, part 12.
577. gbhtg13.seq - HTGS (high throughput genomic sequencing) sequence entries, part 13.
578. gbhtg14.seq - HTGS (high throughput genomic sequencing) sequence entries, part 14.
579. gbhtg15.seq - HTGS (high throughput genomic sequencing) sequence entries, part 15.
580. gbhtg16.seq - HTGS (high throughput genomic sequencing) sequence entries, part 16.
581. gbhtg17.seq - HTGS (high throughput genomic sequencing) sequence entries, part 17.
582. gbhtg18.seq - HTGS (high throughput genomic sequencing) sequence entries, part 18.
583. gbhtg19.seq - HTGS (high throughput genomic sequencing) sequence entries, part 19.
584. gbhtg20.seq - HTGS (high throughput genomic sequencing) sequence entries, part 20.
585. gbhtg21.seq - HTGS (high throughput genomic sequencing) sequence entries, part 21.
586. gbhtg22.seq - HTGS (high throughput genomic sequencing) sequence entries, part 22.
587. gbhtg23.seq - HTGS (high throughput genomic sequencing) sequence entries, part 23.
588. gbhtg24.seq - HTGS (high throughput genomic sequencing) sequence entries, part 24.
589. gbhtg25.seq - HTGS (high throughput genomic sequencing) sequence entries, part 25.
590. gbhtg26.seq - HTGS (high throughput genomic sequencing) sequence entries, part 26.
591. gbhtg27.seq - HTGS (high throughput genomic sequencing) sequence entries, part 27.
592. gbhtg28.seq - HTGS (high throughput genomic sequencing) sequence entries, part 28.
593. gbhtg29.seq - HTGS (high throughput genomic sequencing) sequence entries, part 29.
594. gbhtg30.seq - HTGS (high throughput genomic sequencing) sequence entries, part 30.
595. gbhtg31.seq - HTGS (high throughput genomic sequencing) sequence entries, part 31.
596. gbhtg32.seq - HTGS (high throughput genomic sequencing) sequence entries, part 32.
597. gbhtg33.seq - HTGS (high throughput genomic sequencing) sequence entries, part 33.
598. gbhtg34.seq - HTGS (high throughput genomic sequencing) sequence entries, part 34.
599. gbhtg35.seq - HTGS (high throughput genomic sequencing) sequence entries, part 35.
600. gbhtg36.seq - HTGS (high throughput genomic sequencing) sequence entries, part 36.
601. gbhtg37.seq - HTGS (high throughput genomic sequencing) sequence entries, part 37.
602. gbhtg38.seq - HTGS (high throughput genomic sequencing) sequence entries, part 38.
603. gbhtg39.seq - HTGS (high throughput genomic sequencing) sequence entries, part 39.
604. gbhtg40.seq - HTGS (high throughput genomic sequencing) sequence entries, part 40.
605. gbhtg41.seq - HTGS (high throughput genomic sequencing) sequence entries, part 41.
606. gbhtg42.seq - HTGS (high throughput genomic sequencing) sequence entries, part 42.
607. gbhtg43.seq - HTGS (high throughput genomic sequencing) sequence entries, part 43.
608. gbhtg44.seq - HTGS (high throughput genomic sequencing) sequence entries, part 44.
609. gbhtg45.seq - HTGS (high throughput genomic sequencing) sequence entries, part 45.
610. gbhtg46.seq - HTGS (high throughput genomic sequencing) sequence entries, part 46.
611. gbhtg47.seq - HTGS (high throughput genomic sequencing) sequence entries, part 47.
612. gbhtg48.seq - HTGS (high throughput genomic sequencing) sequence entries, part 48.
613. gbhtg49.seq - HTGS (high throughput genomic sequencing) sequence entries, part 49.
614. gbhtg50.seq - HTGS (high throughput genomic sequencing) sequence entries, part 50.
615. gbhtg51.seq - HTGS (high throughput genomic sequencing) sequence entries, part 51.
616. gbhtg52.seq - HTGS (high throughput genomic sequencing) sequence entries, part 52.
617. gbhtg53.seq - HTGS (high throughput genomic sequencing) sequence entries, part 53.
618. gbhtg54.seq - HTGS (high throughput genomic sequencing) sequence entries, part 54.
619. gbhtg55.seq - HTGS (high throughput genomic sequencing) sequence entries, part 55.
620. gbhtg56.seq - HTGS (high throughput genomic sequencing) sequence entries, part 56.
621. gbhtg57.seq - HTGS (high throughput genomic sequencing) sequence entries, part 57.
622. gbhtg58.seq - HTGS (high throughput genomic sequencing) sequence entries, part 58.
623. gbhtg59.seq - HTGS (high throughput genomic sequencing) sequence entries, part 59.
624. gbhtg60.seq - HTGS (high throughput genomic sequencing) sequence entries, part 60.
625. gbhtg61.seq - HTGS (high throughput genomic sequencing) sequence entries, part 61.
626. gbhtg62.seq - HTGS (high throughput genomic sequencing) sequence entries, part 62.
627. gbhtc1.seq	 - HTC (high throughput cDNA sequencing) entries, part 1.
628. gbhtc2.seq	 - HTC (high throughput cDNA sequencing) entries, part 2.
629. gbhtc3.seq	 - HTC (high throughput cDNA sequencing) entries, part 3.
630. gbhtc4.seq	 - HTC (high throughput cDNA sequencing) entries, part 4.
631. gbcon.seq	 - CON division entries (see description below for details)
632. gbchg.txt   - Accession numbers of entries updated since the previous release.
633. gbdel.txt   - Accession numbers of entries deleted since the previous release.
634. gbnew.txt   - Accession numbers of entries new since the previous release.

  The gbcon.seq data file provides an alternative representation for complex
sequences, such as segmented sets and complete-genomes that have been split
into pieces. These "CON" records do not contain sequence data; they utilize
a CONTIG linetype with a join() statement which describes how the component
sequences can be assembled to form the larger sequence. The contents of the 
CON division are not reflected in the 'index', 'new', 'chg', and 'del' files
that accompany GenBank releases, nor in release statistics (Sections 2.2.6,
2.2.7, and 2.2.8). The GenBank README describes the CON division of GenBank
in more detail:

	ftp://ftp.ncbi.nih.gov/genbank/README.genbank

2.2.5 File Sizes

  Uncompressed, the Release 142.0 flatfiles require roughly 136 GB (sequence
files only) or 153 GB (including the 'short directory', 'index' and the
*.txt files). The following table contains the approximate sizes of the
individual files in this release.  Since minor changes to some of the files
might have occurred after these release notes were written, these sizes should
not be used to determine file integrity; they are provided as an aid to
planning only.

File Size      File Name

1094092495     gbacc.idx
 501001237     gbaut1.idx
 501269250     gbaut10.idx
 510199443     gbaut11.idx
 500172574     gbaut12.idx
 500272312     gbaut13.idx
 502226804     gbaut14.idx
 512574018     gbaut15.idx
 500099644     gbaut16.idx
 505899947     gbaut17.idx
 506994062     gbaut18.idx
 501961608     gbaut19.idx
 500366986     gbaut2.idx
 508420926     gbaut20.idx
 500282002     gbaut21.idx
 500314031     gbaut22.idx
 500058497     gbaut23.idx
 517457852     gbaut24.idx
  26317729     gbaut25.idx
 516628529     gbaut3.idx
 501146250     gbaut4.idx
 519082231     gbaut5.idx
 501134349     gbaut6.idx
 507054654     gbaut7.idx
 502369999     gbaut8.idx
 507059458     gbaut9.idx
 250017376     gbbct1.seq
 250004302     gbbct2.seq
 250138105     gbbct3.seq
 249993816     gbbct4.seq
 250299993     gbbct5.seq
 250009967     gbbct6.seq
 250570017     gbbct7.seq
 249892692     gbbct8.seq
 141196800     gbbct9.seq
   5347988     gbchg.txt
 498807178     gbcon.seq
     65134     gbdel.txt
 230689132     gbest1.seq
 230688600     gbest10.seq
 230689508     gbest100.seq
 230688230     gbest101.seq
 230688169     gbest102.seq
 230688583     gbest103.seq
 230690105     gbest104.seq
 230687989     gbest105.seq
 230690404     gbest106.seq
 230605896     gbest107.seq
 230687451     gbest108.seq
 230689026     gbest109.seq
 230689016     gbest11.seq
 230687990     gbest110.seq
 230688227     gbest111.seq
 230688521     gbest112.seq
 230687496     gbest113.seq
 230688937     gbest114.seq
 230687701     gbest115.seq
 230689445     gbest116.seq
 230688034     gbest117.seq
 230690334     gbest118.seq
 230690331     gbest119.seq
 230688477     gbest12.seq
 230688842     gbest120.seq
 230688435     gbest121.seq
 230689502     gbest122.seq
 230690248     gbest123.seq
 230689256     gbest124.seq
 230689775     gbest125.seq
 230688637     gbest126.seq
 230689208     gbest127.seq
 230690090     gbest128.seq
 230689951     gbest129.seq
 230689137     gbest13.seq
 230688344     gbest130.seq
 230688046     gbest131.seq
 230688094     gbest132.seq
 230690467     gbest133.seq
 230687956     gbest134.seq
 230690441     gbest135.seq
 230688581     gbest136.seq
 230689108     gbest137.seq
 230688708     gbest138.seq
 230688243     gbest139.seq
 230689634     gbest14.seq
 230687498     gbest140.seq
 230687508     gbest141.seq
 230688181     gbest142.seq
 230688663     gbest143.seq
 230688759     gbest144.seq
 230691126     gbest145.seq
 230690387     gbest146.seq
 230687443     gbest147.seq
 230687541     gbest148.seq
 230690200     gbest149.seq
 230690083     gbest15.seq
 230689750     gbest150.seq
 230690297     gbest151.seq
 230690005     gbest152.seq
 230689822     gbest153.seq
 230688829     gbest154.seq
 230688960     gbest155.seq
 230688107     gbest156.seq
 230690388     gbest157.seq
 230690222     gbest158.seq
 230690726     gbest159.seq
 230688068     gbest16.seq
 230688850     gbest160.seq
 230689625     gbest161.seq
 230687848     gbest162.seq
 230691396     gbest163.seq
 230689445     gbest164.seq
 230687445     gbest165.seq
 230689599     gbest166.seq
 230310104     gbest167.seq
 230689946     gbest168.seq
 230688910     gbest169.seq
 230689621     gbest17.seq
 230691086     gbest170.seq
 230689084     gbest171.seq
 230689167     gbest172.seq
 230689215     gbest173.seq
 230689822     gbest174.seq
 230690314     gbest175.seq
 230690186     gbest176.seq
 230690844     gbest177.seq
 230687906     gbest178.seq
 230688796     gbest179.seq
 230689802     gbest18.seq
 230690375     gbest180.seq
 230689388     gbest181.seq
 230688720     gbest182.seq
 230689464     gbest183.seq
 230689588     gbest184.seq
 230688916     gbest185.seq
 230688557     gbest186.seq
 230688541     gbest187.seq
 230691568     gbest188.seq
 230690509     gbest189.seq
 230688799     gbest19.seq
 230690568     gbest190.seq
 230688390     gbest191.seq
 230688922     gbest192.seq
 230688033     gbest193.seq
 230689008     gbest194.seq
 230688707     gbest195.seq
 230688270     gbest196.seq
 230688865     gbest197.seq
 230688899     gbest198.seq
 230689754     gbest199.seq
 230689481     gbest2.seq
 230688740     gbest20.seq
 230689851     gbest200.seq
 230690470     gbest201.seq
 230690505     gbest202.seq
 230692917     gbest203.seq
 165721583     gbest204.seq
 162548168     gbest205.seq
 166146854     gbest206.seq
 170129660     gbest207.seq
 169829644     gbest208.seq
 164118786     gbest209.seq
 230689731     gbest21.seq
 165255453     gbest210.seq
 164665005     gbest211.seq
 164462331     gbest212.seq
 164681420     gbest213.seq
 164380276     gbest214.seq
 164136086     gbest215.seq
 163661500     gbest216.seq
 167949127     gbest217.seq
 162119867     gbest218.seq
 164068475     gbest219.seq
 230688256     gbest22.seq
 168545161     gbest220.seq
 167261132     gbest221.seq
 165946168     gbest222.seq
 165858864     gbest223.seq
 165520033     gbest224.seq
 165269500     gbest225.seq
 164388930     gbest226.seq
 164456575     gbest227.seq
 165609330     gbest228.seq
 167741649     gbest229.seq
 230688401     gbest23.seq
 180424960     gbest230.seq
 170956131     gbest231.seq
 204351582     gbest232.seq
 230689411     gbest233.seq
 230688335     gbest234.seq
 230687498     gbest235.seq
 230687516     gbest236.seq
 230689873     gbest237.seq
 230687469     gbest238.seq
 230687739     gbest239.seq
 230688396     gbest24.seq
 230691157     gbest240.seq
 230687811     gbest241.seq
 230688114     gbest242.seq
 230687913     gbest243.seq
 230688434     gbest244.seq
 230690014     gbest245.seq
 230689379     gbest246.seq
 230689358     gbest247.seq
 230689443     gbest248.seq
 230687674     gbest249.seq
 230689347     gbest25.seq
 230690233     gbest250.seq
 230688741     gbest251.seq
 230689725     gbest252.seq
 230690808     gbest253.seq
 230687605     gbest254.seq
 230689671     gbest255.seq
 230687806     gbest256.seq
 230688617     gbest257.seq
 230690960     gbest258.seq
 230687844     gbest259.seq
 230690653     gbest26.seq
 230690297     gbest260.seq
 207754938     gbest261.seq
 230690912     gbest262.seq
 230689980     gbest263.seq
 230688470     gbest264.seq
 230689994     gbest265.seq
 230689077     gbest266.seq
 230689488     gbest267.seq
 230690693     gbest268.seq
 230687904     gbest269.seq
 230688555     gbest27.seq
 230687898     gbest270.seq
 230688642     gbest271.seq
 230689861     gbest272.seq
 230691236     gbest273.seq
 230687811     gbest274.seq
 230689115     gbest275.seq
 230688202     gbest276.seq
 230687859     gbest277.seq
 230688347     gbest278.seq
 230687885     gbest279.seq
 230689082     gbest28.seq
 230687632     gbest280.seq
 230689234     gbest281.seq
 230687566     gbest282.seq
 230687867     gbest283.seq
 230689571     gbest284.seq
 230687659     gbest285.seq
 230690375     gbest286.seq
 230690417     gbest287.seq
 230691112     gbest288.seq
 230690875     gbest289.seq
 230689872     gbest29.seq
 222137184     gbest290.seq
 155805792     gbest291.seq
 230690249     gbest292.seq
 230689954     gbest293.seq
 230688453     gbest294.seq
 230689863     gbest295.seq
 230689333     gbest296.seq
 230689862     gbest297.seq
 230689744     gbest298.seq
 230689230     gbest299.seq
 230689555     gbest3.seq
 230688133     gbest30.seq
 230688871     gbest300.seq
 230689684     gbest301.seq
 230688783     gbest302.seq
 230692219     gbest303.seq
 230687986     gbest304.seq
 230689994     gbest305.seq
 230692265     gbest306.seq
 230690444     gbest307.seq
 230689530     gbest308.seq
 230689758     gbest309.seq
 230689058     gbest31.seq
 230688449     gbest310.seq
 230688681     gbest311.seq
 230687934     gbest312.seq
 230689966     gbest313.seq
 230688201     gbest314.seq
 230687646     gbest315.seq
 230687614     gbest316.seq
 230690141     gbest317.seq
 223524739     gbest318.seq
 230687727     gbest319.seq
 230688406     gbest32.seq
 230687517     gbest320.seq
  19933519     gbest321.seq
 230688288     gbest33.seq
 230689866     gbest34.seq
 230688478     gbest35.seq
 229366503     gbest36.seq
 191408157     gbest37.seq
 190329541     gbest38.seq
 213443983     gbest39.seq
 230687893     gbest4.seq
 216071978     gbest40.seq
 215846261     gbest41.seq
 216894887     gbest42.seq
 230688911     gbest43.seq
 230687461     gbest44.seq
 227369696     gbest45.seq
 230387383     gbest46.seq
 230688991     gbest47.seq
 230688082     gbest48.seq
 230688687     gbest49.seq
 163953101     gbest5.seq
 230688411     gbest50.seq
 230689704     gbest51.seq
 230688163     gbest52.seq
 230688349     gbest53.seq
 230689694     gbest54.seq
 230688785     gbest55.seq
 230689520     gbest56.seq
 230687609     gbest57.seq
 230690396     gbest58.seq
 230689241     gbest59.seq
 180514745     gbest6.seq
 230688642     gbest60.seq
 230691917     gbest61.seq
 209702259     gbest62.seq
 209361834     gbest63.seq
 208354185     gbest64.seq
 209103080     gbest65.seq
 209842385     gbest66.seq
 210140845     gbest67.seq
 209461780     gbest68.seq
 208459913     gbest69.seq
 230687546     gbest7.seq
 210134383     gbest70.seq
 208147495     gbest71.seq
 205313146     gbest72.seq
 208393023     gbest73.seq
 208080020     gbest74.seq
 211617124     gbest75.seq
 226038921     gbest76.seq
 230689369     gbest77.seq
 230689369     gbest78.seq
 221510648     gbest79.seq
 230689300     gbest8.seq
 214455847     gbest80.seq
 213859355     gbest81.seq
 230689222     gbest82.seq
 230689172     gbest83.seq
 230687931     gbest84.seq
 230688477     gbest85.seq
 230689029     gbest86.seq
 230689104     gbest87.seq
 230687540     gbest88.seq
 230688232     gbest89.seq
 230687459     gbest9.seq
 230689961     gbest90.seq
 230687820     gbest91.seq
 230688921     gbest92.seq
 230688071     gbest93.seq
 230690244     gbest94.seq
 230687464     gbest95.seq
 230690342     gbest96.seq
 230687524     gbest97.seq
 230689371     gbest98.seq
 230689348     gbest99.seq
  37415391     gbgen.idx
 230688486     gbgss1.seq
 230688594     gbgss10.seq
 250002289     gbgss100.seq
 250001805     gbgss101.seq
 250001572     gbgss102.seq
 250002854     gbgss103.seq
 250002040     gbgss104.seq
 250001553     gbgss105.seq
 250003640     gbgss106.seq
 250002221     gbgss107.seq
 250000702     gbgss108.seq
 250002184     gbgss109.seq
 230690231     gbgss11.seq
 112108641     gbgss110.seq
 230688049     gbgss12.seq
 230689543     gbgss13.seq
 230690171     gbgss14.seq
 230688245     gbgss15.seq
 230690296     gbgss16.seq
 230687640     gbgss17.seq
 230687827     gbgss18.seq
 230688676     gbgss19.seq
 230687986     gbgss2.seq
 230689023     gbgss20.seq
 230690916     gbgss21.seq
 230690080     gbgss22.seq
 230689158     gbgss23.seq
 230688311     gbgss24.seq
 230689375     gbgss25.seq
 230687576     gbgss26.seq
 230687630     gbgss27.seq
 230688320     gbgss28.seq
 230687705     gbgss29.seq
 230687901     gbgss3.seq
 230690534     gbgss30.seq
 230688179     gbgss31.seq
 230688390     gbgss32.seq
 230688360     gbgss33.seq
 230688142     gbgss34.seq
 230688663     gbgss35.seq
 230688387     gbgss36.seq
 230687494     gbgss37.seq
 230689000     gbgss38.seq
 230689610     gbgss39.seq
 230687845     gbgss4.seq
 230689557     gbgss40.seq
 230689813     gbgss41.seq
 230687530     gbgss42.seq
 230689127     gbgss43.seq
 230687738     gbgss44.seq
 230688290     gbgss45.seq
 230688229     gbgss46.seq
 230688412     gbgss47.seq
 230687615     gbgss48.seq
 230688420     gbgss49.seq
 230687801     gbgss5.seq
 230688773     gbgss50.seq
 230687676     gbgss51.seq
 230688817     gbgss52.seq
 230687699     gbgss53.seq
 230689919     gbgss54.seq
 230688862     gbgss55.seq
 230690237     gbgss56.seq
 230687775     gbgss57.seq
 230688980     gbgss58.seq
 230687649     gbgss59.seq
 230690143     gbgss6.seq
 230688258     gbgss60.seq
 230148833     gbgss61.seq
 230689960     gbgss62.seq
 230690155     gbgss63.seq
 230687478     gbgss64.seq
 230688521     gbgss65.seq
 230687908     gbgss66.seq
 230688422     gbgss67.seq
 230689430     gbgss68.seq
 230688820     gbgss69.seq
 230687660     gbgss7.seq
 230688221     gbgss70.seq
 230687661     gbgss71.seq
 230688972     gbgss72.seq
 230688503     gbgss73.seq
 230689378     gbgss74.seq
 230689620     gbgss75.seq
 230687774     gbgss76.seq
 230689151     gbgss77.seq
 230689335     gbgss78.seq
 230687776     gbgss79.seq
 230690622     gbgss8.seq
 205544344     gbgss80.seq
 193687138     gbgss81.seq
 213364532     gbgss82.seq
 230689093     gbgss83.seq
 230687888     gbgss84.seq
 230687956     gbgss85.seq
 230689410     gbgss86.seq
 230688582     gbgss87.seq
 230688819     gbgss88.seq
 230688637     gbgss89.seq
 230689742     gbgss9.seq
 230689731     gbgss90.seq
 230687942     gbgss91.seq
 160278782     gbgss92.seq
 250000689     gbgss93.seq
 250002709     gbgss94.seq
 250002244     gbgss95.seq
 250000255     gbgss96.seq
 250000195     gbgss97.seq
 250001730     gbgss98.seq
 250001987     gbgss99.seq
 250000146     gbhtc1.seq
 250002208     gbhtc2.seq
 250001806     gbhtc3.seq
  89344059     gbhtc4.seq
 250045190     gbhtg1.seq
 250050766     gbhtg10.seq
 250204523     gbhtg11.seq
 250171440     gbhtg12.seq
 250318070     gbhtg13.seq
 250108487     gbhtg14.seq
 250524986     gbhtg15.seq
 250214068     gbhtg16.seq
 250118614     gbhtg17.seq
 250072292     gbhtg18.seq
 250012711     gbhtg19.seq
 250075466     gbhtg2.seq
 250121357     gbhtg20.seq
 250213041     gbhtg21.seq
 250111291     gbhtg22.seq
 250146361     gbhtg23.seq
 250451259     gbhtg24.seq
 250133253     gbhtg25.seq
 250064311     gbhtg26.seq
 250209816     gbhtg27.seq
 250156750     gbhtg28.seq
 250301811     gbhtg29.seq
 250115515     gbhtg3.seq
 250196353     gbhtg30.seq
 250262638     gbhtg31.seq
 250173828     gbhtg32.seq
 250118085     gbhtg33.seq
 250372564     gbhtg34.seq
 250301641     gbhtg35.seq
 250300186     gbhtg36.seq
 250034570     gbhtg37.seq
 250247371     gbhtg38.seq
 250260620     gbhtg39.seq
 250226246     gbhtg4.seq
 250117571     gbhtg40.seq
 250055788     gbhtg41.seq
 250187466     gbhtg42.seq
 250057271     gbhtg43.seq
 250112389     gbhtg44.seq
 250198417     gbhtg45.seq
 250209150     gbhtg46.seq
 250112543     gbhtg47.seq
 250026448     gbhtg48.seq
 250178056     gbhtg49.seq
 250021518     gbhtg5.seq
 250212931     gbhtg50.seq
 250159403     gbhtg51.seq
 250205391     gbhtg52.seq
 250026031     gbhtg53.seq
 250167100     gbhtg54.seq
 250085309     gbhtg55.seq
 250019348     gbhtg56.seq
 250169626     gbhtg57.seq
 250157540     gbhtg58.seq
 250257515     gbhtg59.seq
 250175997     gbhtg6.seq
 250195607     gbhtg60.seq
 250490410     gbhtg61.seq
  11869772     gbhtg62.seq
 250139646     gbhtg7.seq
 250179681     gbhtg8.seq
 250042907     gbhtg9.seq
 250125341     gbinv1.seq
 250036227     gbinv2.seq
 250003257     gbinv3.seq
 250000384     gbinv4.seq
 249993904     gbinv5.seq
 214049706     gbinv6.seq
 777780721     gbkey.idx
 221854715     gbmam.seq
  29047550     gbnew.txt
 250023974     gbpat1.seq
 250001045     gbpat10.seq
 250000131     gbpat11.seq
 250005834     gbpat12.seq
 250000365     gbpat13.seq
 250000566     gbpat14.seq
 159229150     gbpat15.seq
 250000547     gbpat2.seq
 250000874     gbpat3.seq
 250000949     gbpat4.seq
 250014316     gbpat5.seq
 250000552     gbpat6.seq
 250000904     gbpat7.seq
 250000946     gbpat8.seq
 250003388     gbpat9.seq
  32266864     gbphg.seq
 250083859     gbpln1.seq
 250012538     gbpln10.seq
 249968998     gbpln11.seq
   5479491     gbpln12.seq
 250226453     gbpln2.seq
 249971308     gbpln3.seq
 250003276     gbpln4.seq
 250138108     gbpln5.seq
 250140855     gbpln6.seq
 250001362     gbpln7.seq
 250000106     gbpln8.seq
 250110106     gbpln9.seq
 250253323     gbpri1.seq
 250165256     gbpri10.seq
 250075024     gbpri11.seq
 250073507     gbpri12.seq
 250203677     gbpri13.seq
 250105912     gbpri14.seq
 250002127     gbpri15.seq
 250000747     gbpri16.seq
 250054068     gbpri17.seq
 250181133     gbpri18.seq
 250095112     gbpri19.seq
 250065713     gbpri2.seq
 250010745     gbpri20.seq
 250191965     gbpri21.seq
 250004376     gbpri22.seq
 250026252     gbpri23.seq
 250097348     gbpri24.seq
 250000052     gbpri25.seq
 250004642     gbpri26.seq
 249989039     gbpri27.seq
  13058933     gbpri28.seq
 250144057     gbpri3.seq
 250190447     gbpri4.seq
 250142335     gbpri5.seq
 250062313     gbpri6.seq
 250074178     gbpri7.seq
 250192144     gbpri8.seq
 250040773     gbpri9.seq
    170050     gbrel.txt
 250230902     gbrod1.seq
 250067333     gbrod10.seq
 250002703     gbrod11.seq
 250047193     gbrod12.seq
  34770711     gbrod13.seq
 250212397     gbrod2.seq
 250060400     gbrod3.seq
 250168063     gbrod4.seq
 250043947     gbrod5.seq
 250077297     gbrod6.seq
 250000208     gbrod7.seq
 250087506     gbrod8.seq
 250035669     gbrod9.seq
   1528991     gbsec.idx
 250001551     gbsts1.seq
 250003453     gbsts2.seq
 250002286     gbsts3.seq
 250001265     gbsts4.seq
  59467482     gbsts5.seq
  52036837     gbsyn.seq
   3047781     gbuna.seq
 249999626     gbvrl1.seq
 249931363     gbvrl2.seq
 249955085     gbvrl3.seq
  55837104     gbvrl4.seq
 249991963     gbvrt1.seq
 250002203     gbvrt2.seq
 225560132     gbvrt3.seq
 250031401     gbvrt4.seq
 250016774     gbvrt5.seq
 192754946     gbvrt6.seq

2.2.6 Per-Division Statistics 

  The following table provides a per-division breakdown of the number of
sequence entries and the total number of bases of DNA/RNA in each non-WGS
sequence data file:

Division     Entries    Bases

BCT1         28788      98084426
BCT2         8692       106067300
BCT3         397        114375595
BCT4         59594      89611609
BCT5         15749      106192310
BCT6         54776      91559251
BCT7         25545      93326963
BCT8         36017      96145118
BCT9         24249      49924099
EST1         68591      26476165
EST10        76948      29968463
EST100       72829      33437629
EST101       69803      29578910
EST102       67406      38244971
EST103       68738      36302932
EST104       68670      43031045
EST105       73435      35199873
EST106       75673      34898189
EST107       75092      27423511
EST108       74239      35925887
EST109       74255      34795797
EST11        76417      28993121
EST110       66842      39647310
EST111       81394      44491935
EST112       77737      45616051
EST113       69965      45512580
EST114       66965      41738814
EST115       75033      50416014
EST116       69971      42572618
EST117       75984      44762576
EST118       74327      46638700
EST119       72259      47883801
EST12        77097      30819336
EST120       74056      51219887
EST121       79311      40043979
EST122       76489      31066903
EST123       79433      40387867
EST124       78018      42671050
EST125       77038      47622266
EST126       61046      28140606
EST127       72620      38953051
EST128       68100      39977840
EST129       66931      36088071
EST13        77755      29954812
EST130       71760      43925751
EST131       73262      44642166
EST132       68033      39377845
EST133       73310      42015045
EST134       70553      43069101
EST135       62839      39400040
EST136       78358      42436746
EST137       99464      54719272
EST138       66773      36883050
EST139       104576     55177669
EST14        80007      32112984
EST140       110285     58782183
EST141       100664     55991292
EST142       81754      48099109
EST143       91942      52648583
EST144       98730      60770051
EST145       72631      42808454
EST146       65225      31724386
EST147       64108      29199844
EST148       53839      25445070
EST149       66691      32424134
EST15        73059      30970804
EST150       57960      29405699
EST151       73154      43390072
EST152       69437      45357436
EST153       70542      49643310
EST154       77056      44155607
EST155       58985      30334007
EST156       65406      33848312
EST157       66702      38364309
EST158       64443      45716741
EST159       63074      36169422
EST16        75614      33241540
EST160       100422     46238660
EST161       89897      52238199
EST162       84692      48443008
EST163       64754      45673009
EST164       70559      36854528
EST165       57041      32681386
EST166       70929      45158839
EST167       73298      27487470
EST168       76671      43677902
EST169       74209      38791253
EST17        84024      34384350
EST170       69095      35221325
EST171       68611      39105296
EST172       70686      52921474
EST173       68963      40568954
EST174       68682      34570371
EST175       69967      53002280
EST176       68881      47070260
EST177       72896      37403543
EST178       68630      46335520
EST179       70836      58844474
EST18        80464      32530977
EST180       64282      47740025
EST181       64033      46972359
EST182       64318      46429661
EST183       65261      46273746
EST184       67790      51562629
EST185       62429      39577642
EST186       63718      35932610
EST187       64090      36787522
EST188       70161      40145938
EST189       92706      51558487
EST19        81044      33619111
EST190       69052      49401485
EST191       92130      54735395
EST192       106991     66190609
EST193       108657     64465793
EST194       107856     64997801
EST195       103074     67027080
EST196       77921      45028818
EST197       70186      44538833
EST198       69970      59611748
EST199       74355      55489866
EST2         75366      28937064
EST20        72961      29221409
EST200       78109      39860994
EST201       80754      48544402
EST202       73086      52412251
EST203       74304      48345092
EST204       27455      10165197
EST205       27882      10595334
EST206       27294      10130934
EST207       26608      9688585
EST208       26731      9068628
EST209       27599      10053234
EST21        73196      34162066
EST210       27260      9838027
EST211       27285      9884554
EST212       27319      10895071
EST213       27206      11848529
EST214       27285      11083028
EST215       27476      9811863
EST216       27607      9137520
EST217       27037      9902760
EST218       27942      11143045
EST219       27673      11058954
EST22        76944      30614408
EST220       26876      11348378
EST221       26800      12178137
EST222       27167      10983393
EST223       27085      11004986
EST224       27095      11955162
EST225       27253      11473448
EST226       27332      10803070
EST227       27318      10918404
EST228       27190      10382696
EST229       26793      12826151
EST23        77267      32135581
EST230       24553      17169378
EST231       26071      17518439
EST232       69457      25817678
EST233       96909      41276912
EST234       74074      46017028
EST235       70138      45103535
EST236       70002      44866054
EST237       69408      42978490
EST238       77370      44891796
EST239       66282      40886763
EST24        75827      34288929
EST240       71487      49307451
EST241       56357      27429103
EST242       99336      47319968
EST243       91074      45325414
EST244       71738      40068897
EST245       62304      29135275
EST246       70511      45381095
EST247       72337      35523087
EST248       72393      34226209
EST249       70693      43968460
EST25        72604      30893576
EST250       69995      37831883
EST251       66201      39275655
EST252       74512      36299726
EST253       86880      48298809
EST254       78016      52897895
EST255       80808      56334065
EST256       110651     49789456
EST257       86678      44292241
EST258       74392      45235362
EST259       73836      40921856
EST26        76648      31598546
EST260       72878      38649878
EST261       69702      27469528
EST262       70613      41642459
EST263       62529      34148284
EST264       66430      43108110
EST265       71887      40932482
EST266       63526      44703687
EST267       64169      32193693
EST268       82736      43937416
EST269       83931      45417326
EST27        78604      34593850
EST270       93770      53309572
EST271       116550     49714985
EST272       101149     44550714
EST273       66663      36216924
EST274       70129      41169608
EST275       77875      45264282
EST276       76028      38756953
EST277       71525      45663414
EST278       70013      37679621
EST279       61924      37735006
EST28        107725     52346911
EST280       49116      25828533
EST281       63795      40367066
EST282       66967      41420714
EST283       72765      41976284
EST284       69292      40481705
EST285       75809      45585072
EST286       61071      52646504
EST287       63611      48126693
EST288       63086      38623589
EST289       67317      41804396
EST29        71527      43460161
EST290       72637      45792218
EST291       58009      28772411
EST292       68596      36597740
EST293       60475      34042198
EST294       64203      32602663
EST295       62234      39343187
EST296       84837      42917488
EST297       71390      42313222
EST298       69176      44149118
EST299       65112      37461554
EST3         74213      30128080
EST30        72069      58602224
EST300       69333      45386075
EST301       93701      52304549
EST302       87284      51889163
EST303       71622      38701796
EST304       57110      36585307
EST305       77226      38203958
EST306       52877      29016969
EST307       54570      29095703
EST308       72065      43579228
EST309       98852      45887516
EST31        85698      49008414
EST310       74798      45919016
EST311       74930      49940139
EST312       80802      52790427
EST313       100535     43899175
EST314       75837      26100856
EST315       72585      26563538
EST316       74175      26642878
EST317       73540      26877579
EST318       78213      26074037
EST319       72795      28973891
EST32        84274      43170200
EST320       73315      28517243
EST321       7656       2416414
EST33        93780      46027156
EST34        100230     48158543
EST35        99471      50721448
EST36        96874      38305090
EST37        69226      18544233
EST38        69423      18463478
EST39        65282      20003105
EST4         74631      28188475
EST40        43582      11803972
EST41        43296      12056612
EST42        43090      11431891
EST43        72759      28458352
EST44        96291      44422472
EST45        93572      46244075
EST46        90620      43419833
EST47        101758     51479957
EST48        102258     52220140
EST49        76413      33051064
EST5         48531      15367560
EST50        67067      29051138
EST51        73841      32839421
EST52        71404      30117948
EST53        80964      32886400
EST54        75516      29794973
EST55        71191      28656190
EST56        64472      29638724
EST57        75853      34147667
EST58        77187      34342037
EST59        74358      29349979
EST6         56332      18258994
EST60        77206      27172065
EST61        84976      39864820
EST62        40317      11538655
EST63        40273      11000858
EST64        40287      12450757
EST65        40629      12569723
EST66        40659      12253536
EST67        40569      12932595
EST68        40394      12889409
EST69        40599      12094067
EST7         74707      29422353
EST70        40255      12037430
EST71        41001      12778029
EST72        41529      11873769
EST73        41216      13143467
EST74        41056      12977804
EST75        42602      12984028
EST76        44809      15937926
EST77        40219      25297119
EST78        42282      20116896
EST79        47837      19338555
EST8         76830      30879168
EST80        51044      22831936
EST81        51541      21690057
EST82        67194      29877108
EST83        71901      27974431
EST84        75926      29803318
EST85        75234      40435377
EST86        78545      41879239
EST87        77972      44502583
EST88        75253      35130349
EST89        75935      43287188
EST9         77951      30110222
EST90        70928      36535683
EST91        75137      36603185
EST92        73696      41389694
EST93        74839      39302027
EST94        71048      40142489
EST95        68987      37029702
EST96        73912      37042854
EST97        72985      46140840
EST98        73559      45920473
EST99        70172      42891664
GSS1         91487      39178813
GSS10        75816      44130824
GSS100       75481      34977640
GSS101       91576      69234634
GSS102       95993      52973052
GSS103       78904      49215365
GSS104       74242      62612090
GSS105       69633      58620004
GSS106       67413      63586004
GSS107       66609      53496485
GSS108       104393     56042067
GSS109       108896     54167634
GSS11        69173      35579720
GSS110       43417      19063499
GSS12        74399      38991314
GSS13        74975      37674241
GSS14        72504      32438642
GSS15        73587      37366102
GSS16        75296      43832006
GSS17        70273      32348402
GSS18        57512      29348258
GSS19        57689      28843040
GSS2         89911      39770582
GSS20        58964      25524452
GSS21        63584      38702909
GSS22        63505      29995854
GSS23        58832      29908648
GSS24        72198      43165906
GSS25        63147      24485474
GSS26        58276      27277779
GSS27        74979      35066573
GSS28        56768      31099571
GSS29        91019      43133399
GSS3         88258      42112413
GSS30        78076      40681053
GSS31        74184      43644470
GSS32        71247      43894434
GSS33        81465      39863878
GSS34        76549      40894147
GSS35        81767      47395297
GSS36        94348      62695292
GSS37        90064      50970061
GSS38        94369      58108236
GSS39        83654      37342621
GSS4         79835      41569189
GSS40        86930      36322321
GSS41        82189      50060467
GSS42        81082      57579492
GSS43        74887      51421385
GSS44        72787      48096880
GSS45        73022      47731178
GSS46        80936      39526105
GSS47        83838      52874332
GSS48        92005      64539495
GSS49        80658      60377919
GSS5         79679      41076797
GSS50        93455      56902639
GSS51        89074      58217847
GSS52        79262      47957270
GSS53        72997      37711478
GSS54        88297      52485489
GSS55        88158      55383634
GSS56        79863      62780655
GSS57        72100      79164727
GSS58        84269      70878035
GSS59        91782      63710288
GSS6         78381      39036861
GSS60        64998      44082240
GSS61        64839      44888727
GSS62        89675      66737951
GSS63        87073      60904360
GSS64        87290      53326465
GSS65        88563      57675512
GSS66        96594      59482669
GSS67        101135     54424422
GSS68        100872     54757390
GSS69        101691     53723622
GSS7         77255      39700569
GSS70        102837     52275058
GSS71        102727     52413695
GSS72        102847     52263364
GSS73        102515     52681599
GSS74        99997      55840610
GSS75        90311      69246622
GSS76        89846      70763473
GSS77        88508      69923114
GSS78        88105      69874659
GSS79        89718      63069864
GSS8         77182      38154928
GSS80        83655      30747504
GSS81        78990      24738155
GSS82        87003      35369247
GSS83        83057      48797272
GSS84        81022      48137561
GSS85        89652      64356874
GSS86        79357      61815867
GSS87        77803      79550725
GSS88        78673      58277238
GSS89        91629      54713744
GSS9         72967      37474282
GSS90        87458      55891440
GSS91        72714      59422514
GSS92        59612      35058755
GSS93        88249      65635082
GSS94        84796      63613729
GSS95        102086     47442993
GSS96        75789      65171775
GSS97        76340      64169954
GSS98        77019      63007982
GSS99        77394      62362776
HTC1         32052      55423415
HTC2         31834      67306459
HTC3         86951      78840760
HTC4         20947      25680867
HTG1         1329       190552749
HTG10        1256       189094891
HTG11        1430       187551911
HTG12        905        192373957
HTG13        751        192651927
HTG14        745        192475833
HTG15        777        192736329
HTG16        800        192353437
HTG17        774        192490109
HTG18        1845       181733898
HTG19        1177       188793779
HTG2         2574       188255115
HTG20        998        190361894
HTG21        1094       189939505
HTG22        789        192223304
HTG23        915        191352848
HTG24        873        192186842
HTG25        897        191537891
HTG26        816        191955898
HTG27        785        192387570
HTG28        881        191840502
HTG29        893        192012857
HTG3         2486       188086194
HTG30        946        191278334
HTG31        958        191350958
HTG32        930        191492347
HTG33        972        191164578
HTG34        894        191939886
HTG35        886        192236245
HTG36        991        191148989
HTG37        884        191867325
HTG38        900        191820737
HTG39        828        192138389
HTG4         2521       189936699
HTG40        878        191714671
HTG41        930        191320232
HTG42        949        191781165
HTG43        937        191787504
HTG44        965        191564222
HTG45        1107       190391395
HTG46        1150       189608587
HTG47        1310       190291018
HTG48        1133       190848080
HTG49        1155       190063518
HTG5         1294       188245488
HTG50        1097       191046807
HTG51        1174       191546565
HTG52        1258       191965093
HTG53        1171       192192773
HTG54        1310       192037919
HTG55        1194       191939456
HTG56        1115       190873531
HTG57        1089       193890767
HTG58        1001       194483698
HTG59        1017       193725528
HTG6         1288       187970479
HTG60        1133       193123619
HTG61        1037       190665635
HTG62        84         8394015
HTG7         1262       188129966
HTG8         1302       187695362
HTG9         1190       189560588
INV1         12929      168740010
INV2         1356       167950230
INV3         56718      93132900
INV4         71996      76711088
INV5         43276      104304965
INV6         39470      87670432
MAM          60421      83578837
PAT1         223219     70408791
PAT10        108267     50638745
PAT11        151419     56282856
PAT12        157986     74549768
PAT13        103445     120727004
PAT14        146500     92069178
PAT15        114560     39690674
PAT2         199580     89443327
PAT3         163733     97025538
PAT4         154179     83573852
PAT5         107664     119373376
PAT6         144802     91232516
PAT7         126271     101537671
PAT8         145843     61509928
PAT9         104631     61049385
PHG          2510       12668047
PLN1         27790      130201006
PLN10        49452      111509292
PLN11        37345      114267581
PLN12        1205       2098490
PLN2         2258       178786688
PLN3         64291      93128966
PLN4         69460      70893454
PLN5         30404      57037745
PLN6         1454       172163410
PLN7         18707      137228501
PLN8         59218      72003614
PLN9         73383      76287330
PRI1         17411      152119736
PRI10        1405       176157572
PRI11        1273       175499086
PRI12        1497       175229415
PRI13        1590       178762533
PRI14        1519       184720749
PRI15        28872      144087231
PRI16        40577      88842912
PRI17        9343       160141549
PRI18        1602       180138153
PRI19        1747       181558550
PRI2         1421       173111031
PRI20        2205       187930178
PRI21        1472       186781377
PRI22        38920      113735447
PRI23        27230      95485838
PRI24        11673      172084588
PRI25        28193      141288827
PRI26        41719      123791110
PRI27        56014      104107811
PRI28        3182       5419678
PRI3         1257       182333250
PRI4         1293       178198566
PRI5         1144       173764460
PRI6         1202       178856128
PRI7         1213       177372978
PRI8         1328       169554514
PRI9         1229       177599460
ROD1         7573       173093806
ROD10        1355       193990031
ROD11        37301      82333051
ROD12        37846      130446921
ROD13        9217       12247707
ROD2         881        174475037
ROD3         897        176357225
ROD4         992        180407338
ROD5         983        180838371
ROD6         991        181622078
ROD7         25446      147520636
ROD8         1722       192633114
ROD9         1199       193116575
STS1         88885      48157763
STS2         74680      30673512
STS3         97643      38071473
STS4         85863      37146108
STS5         26579      11045933
SYN          11690      19955728
UNA          1271       557857
VRL1         72973      65390366
VRL2         73508      65243232
VRL3         75109      66105412
VRL4         13248      18820687
VRT1         65772      93256716
VRT2         10162      167981190
VRT3         63605      58846713
VRT4         41821      141046957
VRT5         1267       193868478
VRT6         45099      80439896

2.2.7 Selected Per-Organism Statistics 

  The following table provides the number of entries and bases of DNA/RNA for
the twenty most sequenced organisms in Release 142.0 (chloroplast and mitochon-
drial sequences not included, and Whole Genome Shotgun sequences not included) :

Entries       Bases   Species

7921258 10662673477   Homo sapiens
5679133  6510495187   Mus musculus
896664   5593182301   Rattus norvegicus
699938   1719817083   Danio rerio
2237983  1406301024   Zea mays
335133    750358559   Oryza sativa (japonica cultivar-group)
376823    708892835   Drosophila melanogaster
651079    546021688   Gallus gallus
722554    531217961   Arabidopsis thaliana
898189    518858629   Canis familiaris
761955    462899090   Bos taurus
193280    426456257   Pan troglodytes
691089    415026837   Ciona intestinalis
508360    413563897   Xenopus tropicalis
595911    403889442   Brassica oleracea
39521     360878971   Macaca mulatta
347927    315519485   Medicago truncatula
555611    304874306   Triticum aestivum
449798    286092539   Xenopus laevis
306304    281281799   Caenorhabditis elegans

2.2.8 Growth of GenBank

  The following table lists the number of bases and the number of sequence
records in each release of GenBank, beginning with Release 3 in 1982.
From 1982 to the present, the number of bases in GenBank has doubled
approximately every 14 months.

Release      Date     Base Pairs   Entries

    3    Dec 1982         680338       606
   14    Nov 1983        2274029      2427
   20    May 1984        3002088      3665
   24    Sep 1984        3323270      4135
   25    Oct 1984        3368765      4175
   26    Nov 1984        3689752      4393
   32    May 1985        4211931      4954
   36    Sep 1985        5204420      5700
   40    Feb 1986        5925429      6642
   42    May 1986        6765476      7416
   44    Aug 1986        8442357      8823
   46    Nov 1986        9615371      9978
   48    Feb 1987       10961380     10913
   50    May 1987       13048473     12534
   52    Aug 1987       14855145     14020
   53    Sep 1987       15514776     14584
   54    Dec 1987       16752872     15465
   55    Mar 1988       19156002     17047
   56    Jun 1988       20795279     18226
   57    Sep 1988       22019698     19044
   57.1  Oct 1988       23800000     20579
   58    Dec 1988       24690876     21248
   59    Mar 1989       26382491     22479
   60    Jun 1989       31808784     26317
   61    Sep 1989       34762585     28791
   62    Dec 1989       37183950     31229
   63    Mar 1990       40127752     33377
   64    Jun 1990       42495893     35100
   65    Sep 1990       49179285     39533
   66    Dec 1990       51306092     41057
   67    Mar 1991       55169276     43903
   68    Jun 1991       65868799     51418
   69    Sep 1991       71947426     55627
   70    Dec 1991       77337678     58952
   71    Mar 1992       83894652     65100
   72    Jun 1992       92160761     71280
   73    Sep 1992      101008486     78608
   74    Dec 1992      120242234     97084
   75    Feb 1993      126212259    106684
   76    Apr 1993      129968355    111911
   77    Jun 1993      138904393    120134
   78    Aug 1993      147215633    131328
   79    Oct 1993      157152442    143492
   80    Dec 1993      163802597    150744
   81    Feb 1994      173261500    162946
   82    Apr 1994      180589455    169896
   83    Jun 1994      191393939    182753
   84    Aug 1994      201815802    196703
   85    Oct 1994      217102462    215273
   86    Dec 1994      230485928    237775
   87    Feb 1995      248499214    269478
   88    Apr 1995      286094556    352414
   89    Jun 1995      318624568    425211
   90    Aug 1995      353713490    492483
   91    Oct 1995      384939485    555694
   92    Dec 1995      425860958    620765
   93    Feb 1996      463758833    685693
   94    Apr 1996      499127741    744295
   95    Jun 1996      551750920    835487
   96    Aug 1996      602072354    920588
   97    Oct 1996      651972984    1021211
   98    Dec 1996      730552938    1114581
   99    Feb 1997      786898138    1192505
   100   Apr 1997      842864309    1274747
   101   Jun 1997      966993087    1491069
   102   Aug 1997     1053474516    1610848
   103   Oct 1997     1160300687    1765847
   104   Dec 1997     1258290513    1891953
   105   Feb 1998     1372368913    2042325
   106   Apr 1998     1502542306    2209232
   107   Jun 1998     1622041465    2355928
   108   Aug 1998     1797137713    2532359
   109   Oct 1998     2008761784    2837897
   110   Dec 1998     2162067871    3043729
   111   Apr 1999     2569578208    3525418
   112   Jun 1999     2974791993    4028171
   113   Aug 1999     3400237391    4610118
   114   Oct 1999     3841163011    4864570
   115   Dec 1999     4653932745    5354511
   116   Feb 2000     5805414935    5691170
   117   Apr 2000     7376080723    6215002
   118   Jun 2000     8604221980    7077491
   119   Aug 2000     9545724824    8214339
   120   Oct 2000    10335692655    9102634
   121   Dec 2000    11101066288    10106023
   122   Feb 2001    11720120326    10896781
   123   Apr 2001    12418544023    11545572
   124   Jun 2001    12973707065    12243766
   125   Aug 2001    13543364296    12813516
   126   Oct 2001    14396883064    13602262
   127   Dec 2001    15849921438    14976310
   128   Feb 2002    17089143893    15465325
   129   Apr 2002    19072679701    16769983
   130   Jun 2002    20648748345    17471130
   131   Aug 2002    22616937182    18197119
   132   Oct 2002    26525934656    19808101
   133   Dec 2002    28507990166    22318883
   134   Feb 2003    29358082791    23035823
   135   Apr 2003    31099264455    24027936
   136   Jun 2003    32528249295    25592865
   137   Aug 2003    33865022251    27213748
   138   Oct 2003    35599621471    29819397
   139   Dec 2003    36553368485    30968418
   140   Feb 2004    37893844733    32549400
   141   Apr 2004    38989342565    33676218
   142   Jun 2004    40325321348    35532003

  The following table lists the number of bases and the number of sequence
records for WGS sequences processed at GenBank, beginning with Release 129.0
in April of 2002.

Release      Date     Base Pairs     Entries

  129    Apr 2002      692266338      172768
  130    Jun 2002     3267608441      397502
  131    Aug 2002     3848375582      427771
  132    Oct 2002     3892435593      434224
  133    Dec 2002     6702372564      597042
  134    Feb 2003     6705740844      597345
  135    Apr 2003     6897080355      596818
  136    Jun 2003     6992663962      607155
  137    Aug 2003     7144761762      593801
  138    Oct 2003     8662242833     1683437
  139    Dec 2003    14523454868     2547094
  140    Feb 2004    22804145885     3188754
  141    Apr 2004    24758556215     4112532
  142    Jun 2004    25592758366     4353890

3. FILE FORMATS

  The flat file examples included in this section, while not always from the
current release, are usually fairly recent.  Any differences compared to the
actual records are the result of updates to the entries involved.

3.1 File Header Information

  With the exception of the index files, gbcon.seq, and the lists of new,
changed, and deleted accession numbers, each of the 634 files of a GenBank
release begins with the same header, except for the first line, which
contains the file name, and the sixth line, which contains the title of
the file. The first line of the file contains the file name in character
positions 1 to 9 and the full database name (Genetic Sequence Data Bank,
aka 'GenBank') starting in column 22. The brief names of the files in this
release are listed in section 2.2.

  The second line contains the date of the current release in the form
`day month year', beginning in position 27. The fourth line contains
the current GenBank release number. The release number appears in
positions 48 to 52 and consists of three numbers separated by a decimal
point. The number to the left of the decimal is the major release
number. The digit to the right of the decimal indicates the version of
the major release; it is zero for the first version. The sixth line
contains a title for the file. The eighth line lists the number of
entries (loci), number of bases (or base pairs), and number of reports
of sequences (equal to number of entries in this case). These numbers are
right-justified at fixed positions. The number of entries appears in
positions 1 to 8, the number of bases in positions 16 to 26, and the
number of reports in positions 40 to 47. The third, fifth, seventh, and
ninth lines are blank.

1       10        20        30        40        50        60        70       79
---------+---------+---------+---------+---------+---------+---------+---------
GBBCT1.SEQ           Genetic Sequence Data Bank
                          15 June 2004

                NCBI-GenBank Flat File Release 142.0

                        Bacterial Sequences (Part 1)

   37811 loci,    97585608 bases, from    37811 reported sequences

---------+---------+---------+---------+---------+---------+---------+---------
1       10        20        30        40        50        60        70       79

Example 1. Sample File Header


3.2 Directory Files

3.2.1 Short Directory File

  The short directory file contains brief descriptions of all of the
sequence entries contained in this release. These descriptions are in
fifteen groups, one group for each of the fifteen sequence entry
data files. The first record at the beginning of a group of entries
contains the name of the group in uppercase characters, beginning in
position 21. The organism groups are PRIMATE, RODENT, OTHER MAMMAL,
OTHER VERTEBRATE, INVERTEBRATE, PLANT, BACTERIAL, STRUCTURAL RNA, VIRAL,
PHAGE, SYNTHETIC, UNANNOTATED, EXPRESSED SEQUENCE TAG, PATENT, or
SEQUENCE TAGGED SITE.  The second record is blank.

  Each record in the short directory contains the sequence entry name
(LOCUS) in the first 12 positions, followed by a brief definition of
the sequence beginning in column 13. The definition is truncated (at
the end of a word) to leave room at the right margin for at least one
space, the sequence length, and the letters `bp'. The length of the
sequence is printed right-justified to column 77, followed by the
letters `bp' in columns 78 and 79. The next-to-last record for a group
has `ZZZZZZZZZZ' in its first ten positions (where the entry name
would normally appear). The last record is a blank line. An example of
the short directory file format, showing the descriptions of the last
entries in the Other Vertebrate sequence data file and the first
entries of the Invertebrate sequence data file, is reproduced below:

1       10        20        30        40        50        60        70       79
---------+---------+---------+---------+---------+---------+---------+---------
ZEFWNT1G3   B.rerio wnt-1 gene (exon 3) for wnt-1 protein.                266bp
ZEFWNT1G4   B.rerio wnt-1 gene (exon 4) for wnt-1 protein.                647bp
ZEFZF54     Zebrafish homeotic gene ZF-54.                                246bp
ZEFZFEN     Zebrafish engrailed-like homeobox sequence.                   327bp
ZZZZZZZZZZ
 
                    INVERTEBRATE

AAHAV33A    Acanthocheilonema viteae pepsin-inhibitor-like-protein       1048bp
ACAAC01     Acanthamoeba castelani gene encoding actin I.                1571bp
ACAACTPH    Acanthamoeba castellanii actophorin mRNA, complete cds.       671bp
ACAMHCA     A.castellanii non-muscle myosin heavy chain gene, partial    5894bp
---------+---------+---------+---------+---------+---------+---------+---------
1       10        20        30        40        50        60        70       79
Example 2. Short Directory File


3.3 Index Files

There are six files containing indices to the entries in this release:

  Accession number index file (Accession and Version)
  Secondary accession number index file
  Keyword phrase index file
  Author name index file
  Journal citation index file
  Gene name index file

  The index keys (accession numbers, keywords, authors, journals, and
gene symbols.) of an index are sorted alphabetically. All index keys
appear in uppercase characters even though they appear in mixed case
in the sequence entries. Following each index key, the identifiers of the
sequence entries containing that key are listed (LOCUS name,
division abbreviation, and primary accession number). The division
abbreviations are:

 1. PRI - primate sequences
 2. ROD - rodent sequences
 3. MAM - other mammalian sequences
 4. VRT - other vertebrate sequences
 5. INV - invertebrate sequences
 6. PLN - plant, fungal, and algal sequences
 7. BCT - bacterial sequences
 8. VRL - viral sequences
 9. PHG - bacteriophage sequences
10. SYN - synthetic sequences
11. UNA - unannotated sequences
12. EST - EST sequences (expressed sequence tags) 
13. PAT - patent sequences
14. STS - STS sequences (sequence tagged sites) 
15. GSS - GSS sequences (genome survey sequences) 
16. HTG - HTGS sequences (high throughput genomic sequences) 
17. HTC - HTC sequences (high throughput cDNA sequences) 

  A line-oriented, TAB-delimited format is utilized for the gbaut.idx,
gbgen.idx,  gbjou.idx, gbkey.idx, and gbsec.idx indexes. Each index
key is presented on its own line, and is followed by a
LOCUS/Division/Accession triplet for every record containing the key:

Indexed-Term 
        LOCUS-name1 Div-code1 Accession1 
        LOCUS-name2 Div-code2 Accession2 
        LOCUS-name3 Div-code3 Accession3 
        .... 

  Here is an example of the format, in which TAB characters are displayed 
as ^I, and carriage-returns/newlines as $ : 

(H+,K+)-ATPASE BETA-SUBUNIT$ 
^IRATHKATPB^IROD^IM55655$ 
^IMUSATP4B1^IROD^IM64685$ 
^IMUSATP4B2^IROD^IM64686$ 
^IMUSATP4B3^IROD^IM64687$ 
^IMUSATP4B4^IROD^IM64688$ 
^IDOGATPASEB^IMAM^IM76486$ 

When viewed by a file browser such as 'less' or 'more' : 

(H+,K+)-ATPASE BETA-SUBUNIT 
        RATHKATPB ROD M55655 
        MUSATP4B1 ROD M64685 
        MUSATP4B2 ROD M64686 
        MUSATP4B3 ROD M64687 
        MUSATP4B4 ROD M64688 
        DOGATPASEB MAM M76486 

  Note that the index keys can be distinguished from LOCUS/DIV/ACCESSION 
by the fact that they do not start with a TAB character. So one can 
extract just the terms via simple text-processing: 

        perl -ne 'print unless /^\s+/' < gbkey.idx > terms.gbkey

  The format of the primary accession number index file is slightly
different, with each indexed key (Accession.Version) present on
the same line as the LOCUS/Division/Accession triplet:

Accession1.Version1 Locus-name1 Div-code1 Accession1 
Accession2.Version2 Locus-name2 Div-code2 Accession2 
.... 

  Here is an example of the format, in which TAB characters are displayed 
as ^I, and carriage-returns/newlines as $ : 

AC000102.1^IAC000102^IPRI^IAC000102$ 
AC000103.1^IAC000103^IPLN^IAC000103$ 
AC000104.1^IF19P19^IPLN^IAC000104$ 
AC000105.40^IAC000105^IPRI^IAC000105$ 
AC000106.1^IF7G19^IPLN^IAC000106$ 
AC000107.1^IAC000107^IPLN^IAC000107$ 
AC000108.1^IAC000108^IBCT^IAC000108$ 
AC000109.1^IHSAC000109^IPRI^IAC000109$ 
AC000110.1^IHSAC000110^IPRI^IAC000110$ 

When viewed by a file browser such as 'less' or 'more' : 

AC000102.1 AC000102 PRI AC000102 
AC000103.1 AC000103 PLN AC000103 
AC000104.1 F19P19 PLN AC000104 
AC000105.40 AC000105 PRI AC000105 
AC000106.1 F7G19 PLN AC000106 
AC000107.1 AC000107 PLN AC000107 
AC000108.1 AC000108 BCT AC000108 
AC000109.1 HSAC000109 PRI AC000109 
AC000110.1 HSAC000110 PRI AC000110 

3.3.1 Accession Number Index File - gbacc.idx

  Accession numbers are unique six character or eight-character alphanumeric
identifiers of GenBank database entries. The six-character accession
number format consists of a single uppercase letter, followed by 5 digits.
The eight-character accession number format consists of two uppercase
letters, followed by 6 digits.  Accessions provide an unchanging identifier
for the data with which they are associated, and we encourage you to cite
accession numbers whenever you refer to data from GenBank.

  GenBank entries can have both 'primary' and 'secondary' accessions
associated with them (see Section 3.5.6). Only primary accessions are present
in the gbacc.idx index.

3.3.2 Keyword Phrase Index File - gbkey.idx

  Keyword phrases consist of names for gene products and other
characteristics of sequence entries.

3.3.3 Author Name Index File - gbaut*.idx

The author name index files list all of the author names that appear
in the references within sequence records.

3.3.4 Journal Citation Index File - gbjou.idx

  The journal citation index file lists all of the citations that appear
in the references within sequence records.. All citations are truncated
to 80 characters.

3.3.5 Gene Name Index - gbgen.idx

  The /gene qualifiers of many GenBank entries contain values other than
official gene symbols, such as the product or the standard name of the gene.
Hence, NCBI has chosen to build an index (gbgen.idx) more like a keyword index
for this field, using both the GenBank /gene qualifier and the 'Gene.locus'
fields from the NCBI internal database as keys.

3.4 Sequence Entry Files

  GenBank releases contain one or more sequence entry data files, one
for each "division" of GenBank.

3.4.1 File Organization

  Each of these files has the same format and consists of two parts:
header information (described in section 3.1) and sequence entries for
that division (described in the following sections).

3.4.2  Entry Organization

  In the second portion of a sequence entry file (containing the
sequence entries for that division), each record (line) consists of
two parts. The first part is found in positions 1 to 10 and may
contain:

1. A keyword, beginning in column 1 of the record (e.g., REFERENCE is
a keyword).

2. A subkeyword beginning in column 3, with columns 1 and 2 blank
(e.g., AUTHORS is a subkeyword of REFERENCE). Or a subkeyword beginning
in column 4, with columns 1, 2, and 3 blank (e.g., PUBMED is a
subkeyword of REFERENCE).

3. Blank characters, indicating that this record is a continuation of
the information under the keyword or subkeyword above it.

4. A code, beginning in column 6, indicating the nature of an entry
(feature key) in the FEATURES table; these codes are described in
Section 3.4.12.1 below.

5. A number, ending in column 9 of the record. This number occurs in
the portion of the entry describing the actual nucleotide sequence and
designates the numbering of sequence positions.

6. Two slashes (//) in positions 1 and 2, marking the end of an entry.

  The second part of each sequence entry record contains the information
appropriate to its keyword, in positions 13 to 80 for keywords and
positions 11 to 80 for the sequence.

  The following is a brief description of each entry field. Detailed
information about each field may be found in Sections 3.4.4 to 3.4.14.

LOCUS	- A short mnemonic name for the entry, chosen to suggest the
sequence's definition. Mandatory keyword/exactly one record.

DEFINITION	- A concise description of the sequence. Mandatory
keyword/one or more records.

ACCESSION	- The primary accession number is a unique, unchanging
code assigned to each entry. (Please use this code when citing
information from GenBank.) Mandatory keyword/one or more records.

VERSION		- A compound identifier consisting of the primary
accession number and a numeric version number associated with the
current version of the sequence data in the record. This is followed
by an integer key (a "GI") assigned to the sequence by NCBI.
Mandatory keyword/exactly one record.

NID		- An alternative method of presenting the NCBI GI
identifier (described above). The NID is obsolete and was removed
from the GenBank flatfile format in December 1999.

KEYWORDS	- Short phrases describing gene products and other
information about an entry. Mandatory keyword in all annotated
entries/one or more records.

SEGMENT	- Information on the order in which this entry appears in a
series of discontinuous sequences from the same molecule. Optional
keyword (only in segmented entries)/exactly one record.

SOURCE	- Common name of the organism or the name most frequently used
in the literature. Mandatory keyword in all annotated entries/one or
more records/includes one subkeyword.

   ORGANISM	- Formal scientific name of the organism (first line)
and taxonomic classification levels (second and subsequent lines).
Mandatory subkeyword in all annotated entries/two or more records.

REFERENCE	- Citations for all articles containing data reported
in this entry. Includes seven subkeywords and may repeat. Mandatory
keyword/one or more records.

   AUTHORS	- Lists the authors of the citation. Optional
subkeyword/one or more records.

   CONSRTM	- Lists the collective names of consortiums associated
with the citation (eg, International Human Genome Sequencing Consortium),
rather than individual author names. Optional subkeyword/one or more records.

   TITLE	- Full title of citation. Optional subkeyword (present
in all but unpublished citations)/one or more records.

   JOURNAL	- Lists the journal name, volume, year, and page
numbers of the citation. Mandatory subkeyword/one or more records.

   MEDLINE	- Provides the Medline unique identifier for a
citation. Optional subkeyword/one record.

    PUBMED 	- Provides the PubMed unique identifier for a
citation. Optional subkeyword/one record.

   REMARK	- Specifies the relevance of a citation to an
entry. Optional subkeyword/one or more records.

COMMENT	- Cross-references to other sequence entries, comparisons to
other collections, notes of changes in LOCUS names, and other remarks.
Optional keyword/one or more records/may include blank records.

FEATURES	- Table containing information on portions of the
sequence that code for proteins and RNA molecules and information on
experimentally determined sites of biological significance. Optional
keyword/one or more records.

BASE COUNT	- Summary of the number of occurrences of each base
code in the sequence. Mandatory keyword/exactly one record.

ORIGIN	- Specification of how the first base of the reported sequence
is operationally located within the genome. Where possible, this
includes its location within a larger genetic map. Mandatory
keyword/exactly one record.

	- The ORIGIN line is followed by sequence data (multiple records).

// 	- Entry termination symbol. Mandatory at the end of an
entry/exactly one record.

3.4.3 Sample Sequence Data File

  An example of a complete sequence entry file follows. (This example
has only two entries.) Note that in this example, as throughout the
data bank, numbers in square brackets indicate items in the REFERENCE
list. For example, in ACARR58S, [1] refers to the paper by Mackay, et
al.

1       10        20        30        40        50        60        70       79
---------+---------+---------+---------+---------+---------+---------+---------
GBSMP.SEQ          Genetic Sequence Data Bank
                         15 December 1992

                 GenBank Flat File Release 74.0

                     Structural RNA Sequences

      2 loci,       236 bases, from     2 reported sequences

LOCUS       AAURRA        118 bp ss-rRNA            RNA       16-JUN-1986
DEFINITION  A.auricula-judae (mushroom) 5S ribosomal RNA.
ACCESSION   K03160
VERSION     K03160.1  GI:173593
KEYWORDS    5S ribosomal RNA; ribosomal RNA.
SOURCE      A.auricula-judae (mushroom) ribosomal RNA.
  ORGANISM  Auricularia auricula-judae
            Eukaryota; Fungi; Eumycota; Basidiomycotina; Phragmobasidiomycetes;
            Heterobasidiomycetidae; Auriculariales; Auriculariaceae.
REFERENCE   1  (bases 1 to 118)
  AUTHORS   Huysmans,E., Dams,E., Vandenberghe,A. and De Wachter,R.
  TITLE     The nucleotide sequences of the 5S rRNAs of four mushrooms and
            their use in studying the phylogenetic position of basidiomycetes
            among the eukaryotes
  JOURNAL   Nucleic Acids Res. 11, 2871-2880 (1983)
FEATURES             Location/Qualifiers
     rRNA            1..118
                     /note="5S ribosomal RNA"
BASE COUNT       27 a     34 c     34 g     23 t
ORIGIN      5' end of mature rRNA.
        1 atccacggcc ataggactct gaaagcactg catcccgtcc gatctgcaaa gttaaccaga
       61 gtaccgccca gttagtacca cggtggggga ccacgcggga atcctgggtg ctgtggtt
//
LOCUS       ABCRRAA       118 bp ss-rRNA            RNA       15-SEP-1990
DEFINITION  Acetobacter sp. (strain MB 58) 5S ribosomal RNA, complete sequence.
ACCESSION   M34766
VERSION     M34766.1  GI:173603
KEYWORDS    5S ribosomal RNA.
SOURCE      Acetobacter sp. (strain MB 58) rRNA.
  ORGANISM  Acetobacter sp.
            Prokaryotae; Gracilicutes; Scotobacteria; Aerobic rods and cocci;
            Azotobacteraceae.
REFERENCE   1  (bases 1 to 118)
  AUTHORS   Bulygina,E.S., Galchenko,V.F., Govorukhina,N.I., Netrusov,A.I.,
            Nikitin,D.I., Trotsenko,Y.A. and Chumakov,K.M.
  TITLE     Taxonomic studies of methylotrophic bacteria by 5S ribosomal RNA
            sequencing
  JOURNAL   J. Gen. Microbiol. 136, 441-446 (1990)
FEATURES             Location/Qualifiers
     rRNA            1..118
                     /note="5S ribosomal RNA"
BASE COUNT       27 a     40 c     32 g     17 t      2 others
ORIGIN      
        1 gatctggtgg ccatggcggg agcaaatcag ccgatcccat cccgaactcg gccgtcaaat
       61 gccccagcgc ccatgatact ctgcctcaag gcacggaaaa gtcggtcgcc gccagayy
//
---------+---------+---------+---------+---------+---------+---------+---------
1       10        20        30        40        50        60        70       79

Example 9. Sample Sequence Data File


3.4.4 LOCUS Format

  The items of information contained in the LOCUS record are always
found in fixed positions. The locus name (or entry name), which is
always sixteen characters or less, begins in position 13. The locus name
is designed to help group entries with similar sequences: the first
three characters usually designate the organism; the fourth and fifth
characters can be used to show other group designations, such as gene
product; for segmented entries the last character is one of a series
of sequential integers.

  The number of bases or base pairs in the sequence ends in position 40.
The letters `bp' are in positions 42 to 43. Positions 45 to 47 provide
the number of strands of the sequence. Positions 48 to 53 indicate the
type of molecule sequenced. Topology of the molecule is indicated in
positions 56 to 63.

  GenBank sequence entries are divided among many different
'divisions'. Each entry's division is specified by a three-letter code
in positions 65 to 67. See Section 3.3 for an explanation of division
codes.

  Positions 69 to 79 of the record contain the date the entry was
entered or underwent any substantial revisions, such as the addition
of newly published data, in the form dd-MMM-yyyy.

The detailed format for the LOCUS line format is as follows:

Positions  Contents
---------  --------
01-05      'LOCUS'
06-12      spaces
13-28      Locus name
29-29      space
30-40      Length of sequence, right-justified
41-41      space
42-43      bp
44-44      space
45-47      spaces, ss- (single-stranded), ds- (double-stranded), or
           ms- (mixed-stranded)
48-53      NA, DNA, RNA, tRNA (transfer RNA), rRNA (ribosomal RNA), 
           mRNA (messenger RNA), uRNA (small nuclear RNA), snRNA,
           snoRNA. Left justified.
54-55      space
56-63      'linear' followed by two spaces, or 'circular'
64-64      space
65-67      The division code (see Section 3.3)
68-68      space
69-79      Date, in the form dd-MMM-yyyy (e.g., 15-MAR-1991)

  Although each of these data values can be found at column-specific
positions, we encourage those who parse the contents of the LOCUS
line to use a token-based approach. This will prevent the need for
software changes if the spacing of the data values ever has to be
modified.

3.4.5 DEFINITION Format

  The DEFINITION record gives a brief description of the sequence,
proceeding from general to specific. It starts with the common name of
the source organism, then gives the criteria by which this sequence is
distinguished from the remainder of the source genome, such as the
gene name and what it codes for, or the protein name and mRNA, or some
description of the sequence's function (if the sequence is
non-coding). If the sequence has a coding region, the description may
be followed by a completeness qualifier, such as cds (complete coding
sequence). There is no limit on the number of lines that may be part
of the DEFINITION.  The last line must end with a period.

3.4.5.1 DEFINITION Format for NLM Entries

  The DEFINITION line for entries derived from journal-scanning at the NLM is
an automatically generated descriptive summary that accompanies each DNA and
protein sequence. It contains information derived from fields in a database 
that summarize the most important attributes of the sequence.  The DEFINITION
lines are designed to supplement the accession number and the sequence itself
as a means of uniquely and completely specifying DNA and protein sequences. The
following are examples of NLM DEFINITION lines:

NADP-specific isocitrate dehydrogenase [swine, mRNA, 1 gene, 1585 nt]

94 kda fiber cell beaded-filament structural protein [rats, lens, mRNA
Partial, 1 gene, 1873 nt]

inhibin alpha {promoter and exons} [mice, Genomic, 1 gene, 1102 nt, segment
1 of 2]

cefEF, cefG=acetyl coenzyme A:deacetylcephalosporin C o-acetyltransferase
[Acremonium chrysogenum, Genomic, 2 genes, 2639 nt]

myogenic factor 3, qmf3=helix-loop-helix protein [Japanese quails,
embryo, Peptide Partial, 246 aa]


  The first part of the definition line contains information describing
the genes and proteins represented by the molecular sequences.  This can
be gene locus names, protein names and descriptions that replace or augment
actual names.  Gene and gene product are linked by "=".  Any special
identifying terms are presented within brackets, such as: {promoter},
{N-terminal}, {EC 2.13.2.4}, {alternatively spliced}, or {3' region}.

  The second part of the definition line is delimited by square brackets, '[]',
and provides details about the molecule type and length.  The biological
source, i.e., genus and species or common name as cited by the author.
Developmental stage, tissue type and strain are included if available.
The molecule types include: Genomic, mRNA, Peptide. and Other Genomic
Material. Genomic molecules are assumed to be partial sequence unless
"Complete" is specified, whereas mRNA and peptide molecules are assumed
to be complete unless "Partial" is noted.

3.4.6 ACCESSION Format

  This field contains a series of six-character and/or eight-character
identifiers called 'accession numbers'. The six-character accession
number format consists of a single uppercase letter, followed by 5 digits.
The eight-character accession number format consists of two uppercase
letters, followed by 6 digits. The 'primary', or first, of the accession
numbers occupies positions 13 to 18 (6-character format) or positions
13 to 20 (8-character format). Subsequent 'secondary' accession numbers
(if present) are separated from the primary, and from each other, by a
single space. In some cases, multiple lines of secondary accession
numbers might be present, starting at position 13.

  The primary accession number of a GenBank entry provides a stable identifier
for the biological object that the entry represents. Accessions do not change
when the underlying sequence data or associated features change.

  Secondary accession numbers arise for a number of reasons. For example, a
single accession number may initially be assigned to a sequence described in
a publication. If it is later discovered that the sequence must be entered
into the database as multiple entries, each entry would receive a new primary
accession number, and the original accession number would appear as a secondary
accession number on each of the new entries.

3.4.7 VERSION Format

  This line contains two types of identifiers for a GenBank database entry:
a compound accession number and an NCBI GI identifier. 

LOCUS       AF181452     1294 bp    DNA             PLN       12-OCT-1999
DEFINITION  Hordeum vulgare dehydrin (Dhn2) gene, complete cds.
ACCESSION   AF181452
VERSION     AF181452.1  GI:6017929
            ^^^^^^^^^^  ^^^^^^^^^^
            Compound    NCBI GI
            Accession   Identifier
            Number

  A compound accession number consists of two parts: a stable, unchanging
primary-accession number portion (see Section 3.4.6 for a description of
accession numbers), and a sequentially increasing numeric version number.
The accession and version numbers are separated by a period. The initial
version number assigned to a new sequence is one. Compound accessions are
often referred to as "Accession.Version" .

  An accession number allows one to retrieve the same biological object in the
database, regardless of any changes that are made to the entry over time. But
those changes can include changes to the sequence data itself, which is of
fundamental importance to many database users. So a numeric version number is
associated with the sequence data in every database entry. If an entry (for
example, AF181452) undergoes two sequence changes, its compound accession
number on the VERSION line would start as AF181452.1 . After the first sequence
change this would become: AF181452.2 . And after the second change: AF181452.3 .

  The NCBI GI identifier of the VERSION line also serves as a method for
identifying the sequence data that has existed for a database entry over
time. GI identifiers are numeric values of one or more digits. Since they
are integer keys, they are less human-friendly than the Accession.Version
system described above. Returning to our example for AF181452, it was
initially assigned GI 6017929. If the sequence changes, a new integer GI will
be assigned, perhaps 7345003 . And after the second sequence change, perhaps
the GI would become 10456892 .

  Why are both these methods for identifying the version of the sequence
associated with a database entry in use? For two reasons:

- Some data sources processed by NCBI for incorporation into its Entrez
  sequence retrieval system do not version their own sequences.

- GIs provide a uniform, integer identifier system for every sequence
  NCBI has processed. Some products and systems derived from (or reliant
  upon) NCBI products and services prefer to use these integer identifiers
  because they can all be processed in the same manner.

GenBank Releases contain only the most recent versions of all sequences
in the database. However, older versions can be obtained via GI-based or
Accession.Version-based queries with NCBI's web-Entrez and network-Entrez
applications. A sequence revision history web page is also available:

	  http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/htbin-post/Entrez/girevhist

NOTE: All the version numbers for the compound Accession.Version identifier
system were initialized to a value of one in February 1999, when that
system was introduced.

3.4.8 KEYWORDS Format

  The KEYWORDS field does not appear in unannotated entries, but is
required in all annotated entries. Keywords are separated by
semicolons; a "keyword" may be a single word or a phrase consisting of
several words. Each line in the keywords field ends in a semicolon;
the last line ends with a period. If no keywords are included in the
entry, the KEYWORDS record contains only a period.

3.4.9 SEGMENT Format

  The SEGMENT keyword is used when two (or more) entries of known
relative orientation are separated by a short (<10 kb) stretch of DNA.
It is limited to one line of the form `n of m', where `n' is the
segment number of the current entry and `m' is the total number of
segments.

3.4.10 SOURCE Format

  The SOURCE field consists of two parts. The first part is found after
the SOURCE keyword and contains free-format information including an
abbreviated form of the organism name followed by a molecule type;
multiple lines are allowed, but the last line must end with a period.
The second part consists of information found after the ORGANISM
subkeyword. The formal scientific name for the source organism (genus
and species, where appropriate) is found on the same line as ORGANISM.
The records following the ORGANISM line list the taxonomic
classification levels, separated by semicolons and ending with a
period.

3.4.11 REFERENCE Format

  The REFERENCE field consists of five parts: the keyword REFERENCE, and
the subkeywords AUTHORS, TITLE (optional), JOURNAL, MEDLINE (optional),
PUBMED (optional), and REMARK (optional).

  The REFERENCE line contains the number of the particular reference and
(in parentheses) the range of bases in the sequence entry reported in
this citation. Additional prose notes may also be found within the
parentheses. The numbering of the references does not reflect
publication dates or priorities.

  The AUTHORS line lists the authors in the order in which they appear
in the cited article. Last names are separated from initials by a
comma (no space); there is no comma before the final `and'. The list
of authors ends with a period.  The TITLE line is an optional field,
although it appears in the majority of entries. It does not appear in
unpublished sequence data entries that have been deposited directly
into the GenBank data bank, the EMBL Nucleotide Sequence Data Library,
or the DNA Data Bank of Japan. The TITLE field does not end with a
period.

  The JOURNAL line gives the appropriate literature citation for the
sequence in the entry. The word `Unpublished' will appear after the
JOURNAL subkeyword if the data did not appear in the scientific
literature, but was directly deposited into the data bank. For
published sequences the JOURNAL line gives the Thesis, Journal, or
Book citation, including the year of publication, the specific
citation, or In press.

  For Book citations, the JOURNAL line is specially-formatted, and
includes:

	editor name(s)
	book title
	page number(s)
	publisher-name/publisher-location
	year

For example:

LOCUS       AY277550                1440 bp    DNA     linear   BCT 17-JUN-2003
DEFINITION  Stenotrophomonas maltophilia strain CSC13-6 16S ribosomal RNA gene,
            partial sequence.
ACCESSION   AY277550
....
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Gonzalez,J.M., Laiz,L. and Saiz-Jimenez,C.
  TITLE     Classifying bacterial isolates from hypogean environments:
            Application of a novel fluorimetric method dor the estimation of
            G+C mol% content in microorganisms by thermal denaturation
            temperature
  JOURNAL   (in) Saiz-Jimenez,C. (Ed.);
            MOLECULAR BIOLOGY AND CULTURAL HERITAGE: 47-54;
            A.A. Balkema, The Netherlands (2003)

  The presence of "(in)" signals the fact that the reference is for a book
rather than a journal article. A semi-colon signals the end of the editor
names. The next semi-colon signals the end of the page numbers, and the
colon that immediately *precedes* the page numbers signals the end of the
book title. The publisher name and location are a free-form text string.
Finally, the year appears at the very end of the JOURNAL line, enclosed in
parentheses.

  The MEDLINE line provides the National Library of Medicine's Medline
unique identifier for a citation (if known). Medline UIs are 8 digit
numbers.

  The PUBMED line provides the PubMed unique identifier for a citation
(if known). PUBMED ids are numeric, and are record identifiers for article
abstracts in the PubMed database :

       http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/entrez/query.fcgi?db=PubMed

  Citations in PubMed that do not fall within Medline's scope will have only
a PUBMED identifier. Similarly, citations that *are* in Medline's scope but
which have not yet been assigned Medline UIs will have only a PUBMED identifier.
If a citation is present in both the PubMed and Medline databases, both a
MEDLINE and a PUBMED line will be present.

  The REMARK line is a textual comment that specifies the relevance
of the citation to the entry.

3.4.12 FEATURES Format

  GenBank releases use a feature table format designed jointly by
GenBank, the EMBL Nucleotide Sequence Data Library, and the DNA Data
Bank of Japan. This format is in use by all three databases. The
most complete and accurate Feature Table documentation can be found
on the Web at:

	http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/collab/FT/index.html

  Any discrepancy between the abbreviated feature table description
of these release notes and the complete documentation on the Web
should be resolved in favor of the version at the above URL.

  The Feature Table specification is also available as a printed
document: `The DDBJ/EMBL/GenBank Feature Table: Definition'. Contact
GenBank at the address shown on the first page of these Release Notes
if you would like a copy.

  The feature table contains information about genes and gene products,
as well as regions of biological significance reported in the
sequence. The feature table contains information on regions of the
sequence that code for proteins and RNA molecules. It also enumerates
differences between different reports of the same sequence, and
provides cross-references to other data collections, as described in
more detail below.

  The first line of the feature table is a header that includes the
keyword `FEATURES' and the column header `Location/Qualifier.' Each
feature consists of a descriptor line containing a feature key and a
location (see sections below for details). If the location does not
fit on this line, a continuation line may follow. If further
information about the feature is required, one or more lines
containing feature qualifiers may follow the descriptor line.

  The feature key begins in column 6 and may be no more than 15
characters in length. The location begins in column 22. Feature
qualifiers begin on subsequent lines at column 22. Location,
qualifier, and continuation lines may extend from column 22 to 80.

  Feature tables are required, due to the mandatory presence of the
source feature. The sections below provide a brief introduction to
the feature table format.

3.4.12.1 Feature Key Names

  The first column of the feature descriptor line contains the feature
key. It starts at column 6 and can continue to column 20. The list of
valid feature keys is shown below.

  Remember, the most definitive documentation for the feature table can
be found at:

	http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/collab/FT/index.html

allele		Obsolete; see variation feature key
attenuator	Sequence related to transcription termination
C_region	Span of the C immunological feature
CAAT_signal	`CAAT box' in eukaryotic promoters
CDS		Sequence coding for amino acids in protein (includes
		stop codon)
conflict	Independent sequence determinations differ
D-loop      	Displacement loop
D_segment	Span of the D immunological feature
enhancer	Cis-acting enhancer of promoter function
exon		Region that codes for part of spliced mRNA
gene            Region that defines a functional gene, possibly
                including upstream (promotor, enhancer, etc)
		and downstream control elements, and for which
		a name has been assigned.
GC_signal	`GC box' in eukaryotic promoters
iDNA		Intervening DNA eliminated by recombination
intron		Transcribed region excised by mRNA splicing
J_region	Span of the J immunological feature
LTR		Long terminal repeat
mat_peptide	Mature peptide coding region (does not include stop codon)
misc_binding	Miscellaneous binding site
misc_difference	Miscellaneous difference feature
misc_feature	Region of biological significance that cannot be described
		by any other feature
misc_recomb	Miscellaneous recombination feature
misc_RNA	Miscellaneous transcript feature not defined by other RNA keys
misc_signal	Miscellaneous signal
misc_structure	Miscellaneous DNA or RNA structure
modified_base	The indicated base is a modified nucleotide
mRNA		Messenger RNA
mutation 	Obsolete: see variation feature key
N_region	Span of the N immunological feature
old_sequence	Presented sequence revises a previous version
polyA_signal	Signal for cleavage & polyadenylation
polyA_site	Site at which polyadenine is added to mRNA
precursor_RNA	Any RNA species that is not yet the mature RNA product
prim_transcript	Primary (unprocessed) transcript
primer		Primer binding region used with PCR
primer_bind	Non-covalent primer binding site
promoter	A region involved in transcription initiation
protein_bind	Non-covalent protein binding site on DNA or RNA
RBS		Ribosome binding site
rep_origin	Replication origin for duplex DNA
repeat_region	Sequence containing repeated subsequences
repeat_unit	One repeated unit of a repeat_region
rRNA		Ribosomal RNA
S_region	Span of the S immunological feature
satellite	Satellite repeated sequence
scRNA		Small cytoplasmic RNA
sig_peptide	Signal peptide coding region
snRNA		Small nuclear RNA
source		Biological source of the sequence data represented by
		a GenBank record. Mandatory feature, one or more per record.
		For organisms that have been incorporated within the
		NCBI taxonomy database, an associated /db_xref="taxon:NNNN"
		qualifier will be present (where NNNNN is the numeric
		identifier assigned to the organism within the NCBI taxonomy
		database).
stem_loop	Hair-pin loop structure in DNA or RNA
STS		Sequence Tagged Site; operationally unique sequence that
		identifies the combination of primer spans used in a PCR assay
TATA_signal	`TATA box' in eukaryotic promoters
terminator	Sequence causing transcription termination
transit_peptide	Transit peptide coding region
transposon	Transposable element (TN)
tRNA 		Transfer RNA
unsure		Authors are unsure about the sequence in this region
V_region	Span of the V immunological feature
variation 	A related population contains stable mutation
- (hyphen)	Placeholder
-10_signal	`Pribnow box' in prokaryotic promoters
-35_signal	`-35 box' in prokaryotic promoters
3'clip		3'-most region of a precursor transcript removed in processing
3'UTR		3' untranslated region (trailer)
5'clip		5'-most region of a precursor transcript removed in processing
5'UTR		5' untranslated region (leader)


3.4.12.2 Feature Location

  The second column of the feature descriptor line designates the
location of the feature in the sequence. The location descriptor
begins at position 22. Several conventions are used to indicate
sequence location.

  Base numbers in location descriptors refer to numbering in the entry,
which is not necessarily the same as the numbering scheme used in the
published report. The first base in the presented sequence is numbered
base 1. Sequences are presented in the 5 to 3 direction.

Location descriptors can be one of the following:

1. A single base;

2. A contiguous span of bases;

3. A site between two bases;

4. A single base chosen from a range of bases;

5. A single base chosen from among two or more specified bases;

6. A joining of sequence spans;

7. A reference to an entry other than the one to which the feature
belongs (i.e., a remote entry), followed by a location descriptor
referring to the remote sequence;

  A site between two residues, such as an endonuclease cleavage site, is
indicated by listing the two bases separated by a carat (e.g., 23^24).

  A single residue chosen from a range of residues is indicated by the
number of the first and last bases in the range separated by a single
period (e.g., 23.79). The symbols < and > indicate that the end point
of the range is beyond the specified base number.

  A contiguous span of bases is indicated by the number of the first and
last bases in the range separated by two periods (e.g., 23..79). The
symbols < and > indicate that the end point of the range is beyond the
specified base number. Starting and ending positions can be indicated
by base number or by one of the operators described below.

  Operators are prefixes that specify what must be done to the indicated
sequence to locate the feature. The following are the operators
available, along with their most common format and a description.

complement (location): The feature is complementary to the location
indicated. Complementary strands are read 5 to 3.

join (location, location, .. location): The indicated elements should
be placed end to end to form one contiguous sequence.

order (location, location, .. location): The elements are found in the
specified order in the 5 to 3 direction, but nothing is implied about
the rationality of joining them.

3.4.12.3  Feature Qualifiers

  Qualifiers provide additional information about features. They take
the form of a slash (/) followed by a qualifier name and, if
applicable, an equal sign (=) and a qualifier value. Feature
qualifiers begin at column 22.

Qualifiers convey many types of information. Their values can,
therefore, take several forms:

1. Free text;
2. Controlled vocabulary or enumerated values;
3. Citations or reference numbers;
4. Sequences;
5. Feature labels.

  Text qualifier values must be enclosed in double quotation marks. The
text can consist of any printable characters (ASCII values 32-126
decimal). If the text string includes double quotation marks, each set
must be `escaped' by placing a double quotation mark in front of it
(e.g., /note="This is an example of ""escaped"" quotation marks").

  Some qualifiers require values selected from a limited set of choices.
For example, the `/direction' qualifier has only three values `left,'
`right,' or `both.' These are called controlled vocabulary qualifier
values. Controlled qualifier values are not case sensitive; they can
be entered in any combination of upper- and lowercase without changing
their meaning.

  Citation or published reference numbers for the entry should be
enclosed in square brackets ([]) to distinguish them from other
numbers.

  A literal sequence of bases (e.g., "atgcatt") should be enclosed in
quotation marks. Literal sequences are distinguished from free text by
context. Qualifiers that take free text as their values do not take
literal sequences, and vice versa.

  The `/label=' qualifier takes a feature label as its qualifier.
Although feature labels are optional, they allow unambiguous
references to the feature. The feature label identifies a feature
within an entry; when combined with the accession number and the name
of the data bank from which it came, it is a unique tag for that
feature. Feature labels must be unique within an entry, but can be the
same as a feature label in another entry. Feature labels are not case
sensitive; they can be entered in any combination of upper-and
lowercase without changing their meaning.

The following is a partial list of feature qualifiers.

/anticodon	Location of the anticodon of tRNA and the amino acid
		for which it codes

/bound_moiety	Moiety bound

/citation	Reference to a citation providing the claim of or
		evidence for a feature

/codon		Specifies a codon that is different from any found in the
		reference genetic code

/codon_start	Indicates the first base of the first complete codon
		in a CDS (as 1 or 2 or 3)

/cons_splice	Identifies intron splice sites that do not conform to
		the 5'-GT... AG-3' splice site consensus

/db_xref	A database cross-reference; pointer to related information
		in another database. A description of all cross-references
		can be found at:

		http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/collab/db_xref.html

/direction	Direction of DNA replication

/EC_number	Enzyme Commission number for the enzyme product of the
		sequence

/evidence	Value indicating the nature of supporting evidence

/frequency	Frequency of the occurrence of a feature

/function	Function attributed to a sequence

/gene		Symbol of the gene corresponding to a sequence region (usable
		with all features)

/label		A label used to permanently identify a feature

/map		Map position of the feature in free-format text

/mod_base	Abbreviation for a modified nucleotide base

/note		Any comment or additional information

/number		A number indicating the order of genetic elements
		(e.g., exons or introns) in the 5 to 3 direction

/organism	Name of the organism that is the source of the
		sequence data in the record. 

/partial	Differentiates between complete regions and partial ones

/phenotype	Phenotype conferred by the feature

/product	Name of a product encoded by a coding region (CDS)
		feature

/pseudo		Indicates that this feature is a non-functional
		version of the element named by the feature key

/rpt_family	Type of repeated sequence; Alu or Kpn, for example

/rpt_type	Organization of repeated sequence

/rpt_unit	Identity of repeat unit that constitutes a repeat_region

/standard_name	Accepted standard name for this feature

/transl_except	Translational exception: single codon, the translation
		of which does not conform to the reference genetic code

/translation	Amino acid translation of a coding region

/type		Name of a strain if different from that in the SOURCE field

/usedin		Indicates that feature is used in a compound feature
		in another entry

3.4.12.4 Cross-Reference Information

  One type of information in the feature table lists cross-references to
the annual compilation of transfer RNA sequences in Nucleic Acids
Research, which has kindly been sent to us on CD-ROM by Dr. Sprinzl.
Each tRNA entry of the feature table contains a /note= qualifier that
includes a reference such as `(NAR: 1234)' to identify code 1234 in
the NAR compilation. When such a cross-reference appears in an entry
that contains a gene coding for a transfer RNA molecule, it refers to
the code in the tRNA gene compilation. Similar cross-references in
entries containing mature transfer RNA sequences refer to the
companion compilation of tRNA sequences published by D.H. Gauss and M.
Sprinzl in Nucleic Acids Research.

3.4.12.5 Feature Table Examples

  In the first example a number of key names, feature locations, and
qualifiers are illustrated, taken from different sequences. The first
table entry is a coding region consisting of a simple span of bases
and including a /gene qualifier. In the second table entry, an NAR
cross-reference is given (see the previous section for a discussion of
these cross-references). The third and fourth table entries use the
symbols `<`and `>' to indicate that the beginning or end of the
feature is beyond the range of the presented sequence. In the fifth
table entry, the symbol `^' indicates that the feature is between
bases.

1       10        20        30        40        50        60        70       79
---------+---------+---------+---------+---------+---------+---------+---------
     CDS             5..1261
                     /product="alpha-1-antitrypsin precursor"
                     /map="14q32.1"
                     /gene="PI"
     tRNA            1..87
                     /note="Leu-tRNA-CAA (NAR: 1057)"
                     /anticodon=(pos:35..37,aa:Leu)
     mRNA            1..>66
                     /note="alpha-1-acid glycoprotein mRNA"
     transposon      <1..267
                     /note="insertion element IS5"
     misc_recomb     105^106
                     /note="B.subtilis DNA end/IS5 DNA start"
     conflict        258
                     /replace="t"
                     /citation=[2]
---------+---------+---------+---------+---------+---------+---------+---------
1       10        20        30        40        50        60        70       79

Example 10. Feature Table Entries


The next example shows the representation for a CDS that spans more
than one entry.

1       10        20        30        40        50        60        70       79
---------+---------+---------+---------+---------+---------+---------+---------
LOCUS       HUMPGAMM1    3688 bp ds-DNA             PRI       15-OCT-1990
DEFINITION  Human phosphoglycerate mutase (muscle specific isozyme) (PGAM-M)
            gene, 5' end.
ACCESSION   M55673 M25818 M27095
KEYWORDS    phosphoglycerate mutase.
SEGMENT     1 of 2
  .
  .
  .
FEATURES             Location/Qualifiers
     CAAT_signal     1751..1755
                     /gene="PGAM-M"
     TATA_signal     1791..1799
                     /gene="PGAM-M"
     exon            1820..2274
                     /number=1
                     /EC_number="5.4.2.1"
                     /gene="PGAM-M"
     intron          2275..2377
                     /number=1
                     /gene="PGAM2"
     exon            2378..2558
                     /number=2
                     /gene="PGAM-M"
  .
  .
  .
//
LOCUS       HUMPGAMM2     677 bp ds-DNA             PRI       15-OCT-1990
DEFINITION  Human phosphoglycerate mutase (muscle specific isozyme) (PGAM-M),
            exon 3.
ACCESSION   M55674 M25818 M27096
KEYWORDS    phosphoglycerate mutase.
SEGMENT     2 of 2
  .
  .
  .
FEATURES             Location/Qualifiers
     exon            255..457
                     /number=3
                     /gene="PGAM-M"
     intron          order(M55673:2559..>3688,<1..254)
                     /number=2
                     /gene="PGAM-M"
     mRNA            join(M55673:1820..2274,M55673:2378..2558,255..457)
                     /gene="PGAM-M"
     CDS             join(M55673:1861..2274,M55673:2378..2558,255..421)
                     /note="muscle-specific isozyme"
                     /gene="PGAM2"
                     /product="phosphoglycerate mutase"
                     /codon_start=1
                     /translation="MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKA
                     IKDAKMEFDICYTSVLKRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAE
                     TAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTI
                     ARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVY
                     ELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK"
  .
  .
  .
//
---------+---------+---------+---------+---------+---------+---------+---------
1       10        20        30        40        50        60        70       79

Example 11. Joining Sequences


3.4.13 ORIGIN Format

  The ORIGIN record may be left blank, may appear as `Unreported.' or
may give a local pointer to the sequence start, usually involving an
experimentally determined restriction cleavage site or the genetic
locus (if available). The ORIGIN record ends in a period if it
contains data, but does not include the period if the record is left
empty (in contrast to the KEYWORDS field which contains a period
rather than being left blank).

3.4.14 SEQUENCE Format

  The nucleotide sequence for an entry is found in the records following
the ORIGIN record. The sequence is reported in the 5 to 3 direction.
There are sixty bases per record, listed in groups of ten bases
followed by a blank, starting at position 11 of each record. The
number of the first nucleotide in the record is given in columns 4 to
9 (right justified) of the record.


4. ALTERNATE RELEASES

  NCBI is supplying sequence data in the GenBank flat file format to
maintain compatibility with existing software which require that
particular format.  Although we have made every effort to ensure
that these data are presented in the traditional flat file format,
if you encounter any problems in using these data with software which
is based upon the flat file format, please contact us at:

              info@ncbi.nlm.nih.gov

  The flat file is just one of many possible report formats that can be
generated from the richer representation supported by the ASN.1 form of the
data.  Developers of new software tools should consider using the ASN.1 form
directly to take advantage of those features.  Documentation and a Software
Developer's Toolkit for ASN.1 are available through NCBI.  You may call NCBI
at (301)496-2475, or subscribe to a developers' electronic newsgroup by
sending your name, address, affiliation, and e-mail address to:

              bits-request@ncbi.nlm.nih.gov

  The Software Developer's Toolkit and PostScript documentation for UNIX,
VMS, Ultrix, AIX, MacOS, DOS, and Microsoft Windows systems is available
in a compressed UNIX tar file by anonymous ftp from 'ftp.ncbi.nih.gov',
in the toolbox/ncbi_tools directory. The file is 'ncbi.tar.Z'.


5. KNOWN PROBLEMS OF THE GENBANK DATABASE

5.1 Incorrect Gene Symbols in Entries and Index

  The /gene qualifier for many GenBank entries contains values other than the
official gene symbol, such as the product or the standard name of the gene. The
gene symbol index (gbgen.idx) is created from the data in the /gene qualifier
and therefore may contain data other than official gene symbols.


6. GENBANK ADMINISTRATION 

  The National Center for Biotechnology Information (NCBI), National Library
of Medicine, National Institutes of Health, is responsible for the production
and distribution of the NIH GenBank Sequence Database.  NCBI distributes
GenBank sequence data by anonymous FTP, e-mail servers and other
network services.  For more information, you may contact NCBI at the
e-mail address:  info@ncbi.nlm.nih.gov  or by phone: 301-496-2475.

6.1 Registered Trademark Notice

  GenBank (R) is a registered trademark of the U.S. Department of Health
and Human Services for the Genetic Sequence Data Bank.

6.2 Citing GenBank

  If you have used GenBank in your research, we would appreciate it if
you would include a reference to GenBank in all publications related
to that research.

  When citing data in GenBank, it is appropriate to give the sequence
name, primary accession number, and the publication in which the
sequence first appeared.  If the data are unpublished, we urge you to
contact the group which submitted the data to GenBank to see if there
is a recent publication or if they have determined any revisions or
extensions of the data.

  It is also appropriate to list a reference for GenBank itself.  The
following publication, which describes the GenBank database, should
be cited:

    Benson D.A., Karsch-Mizrachi I., Lipman D.J., Ostell J., Rapp B.A., 
    Wheeler D.L.  GenBank. Nucl. Acids Res. 28(1):15-18 (2000)

  The following statement is an example of how you may cite GenBank
data.  It cites the sequence, its primary accession number, the group
who determined the sequence, and GenBank.  The numbers in parentheses
refer to the GenBank citation above and to the REFERENCE in the
GenBank sequence entry.

`We scanned the GenBank (1) database for sequence similarities and
found one sequence (2), GenBank accession number J01016, which showed
significant similarity...'

  (1) Benson, D.A. et al. Nucl. Acids Res. 28(1):15-18 (2000)
  (2) Nellen, W. and Gallwitz, D. J. Mol. Biol. 159, 1-18 (1982)

6.3 GenBank Distribution Formats and Media

  Complete flat file releases of the GenBank database are available via
NCBI's anonymous ftp server:

	ftp://ftp.ncbi.nih.gov

  Each release is cumulative, incorporating all previous GenBank data.
No retrieval software is provided. GenBank distribution via CD-ROM
ceased as of GenBank Release 106.0 (April, 1998).

  Mirrors of the GenBank FTP site at the NCBI are available from the
San Diego Supercomputer Center and the University of Indiana:

	ftp://genbank.sdsc.edu/pub
	ftp://bio-mirror.net/biomirror/genbank/

6.4 Other Methods of Accessing GenBank Data

  Entrez is a molecular biology database system that presents an integrated
view of DNA and protein sequence data, 3D structure data, complete genomes,
and associated MEDLINE entries. The system is produced by the National
Center for Biotechnology Information (NCBI), and is available only via
the Internet (using the Web-Entrez and Network-Entrez applications).

  Accessing Entrez is easy: if you have a World Wide Web browser, such as
Netscape or Internet-Explorer, simply point your browser to:

	 http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/

  The Web version of Entrez has all the capabilities of the network version,
but with the visual style of the World Wide Web. If you prefer the "look and
feel" of Network-Entrez, you may download Network-Entrez from the NCBI's
FTP server:

	ftp://ftp.ncbi.nih.gov/

Versions are available for PC/Windows, Macintosh and several Unix variants.

  For information about Network-Entrez, Web-Entrez or any other NCBI
services, you may contact NCBI by e-mail at info@ncbi.nlm.nih.gov or by
phone at 301-496-2475.

6.5 Request for Corrections and Comments

  We welcome your suggestions for improvements to GenBank. We are
especially interested to learn of errors or inconsistencies in the
data.  BankIt or Sequin can be used to submit revisions to previous
submissions.  In addition, suggestions and corrections can be sent by
electronic mail to:  update@ncbi.nlm.nih.gov.  Please be certain to
indicate the GenBank release number (e.g., Release 142.0) and the
primary accession number of the entry to which your comments apply; it
is helpful if you also give the entry name and the current contents of
any data field for which you are recommending a change.

6.6  Credits and Acknowledgments

Credits -

GenBank Release Coordination	
	Mark Cavanaugh

GenBank Submission Coordination	
	Ilene Mizrachi

GenBank Annotation Staff
	Lori Black, Larissa Brown, Larry Chlumsky, Karen Clark, Irene Fang,
	Linda Frisse, Michael Fetchko, Anjanette Johnston, William Klimke,
	Pierre Ledoux, Richard McVeigh, Ilene Mizrachi, DeAnne Olsen Cravaritis,
	Chris O'Sullivan, Leigh Riley, Gert Roosen, MJ Rosovitz, Susan Schafer,
	Suh-suh Wang, and Linda Yankie

Data Management and Preparation
	Vladimir Alekseyev, Serge Bazhin, Anton Butanaev, Mark Cavanaugh,
	Hsiu-Chuan Chen, Olga Cherenkov, Jonathan Kans, Michael Kimelman,
	Jim Ostell, Karl Sirotkin, Vladimir Soussov, Elena Starchenko,
	Hanzhen Sun, Tatiana Tatusova, Carolyn Tolstoshev, Jane Weisemann,
	Eugene Yaschenko

Database Administration
	Slava Khotomliansky, Joe Pepersack, Tony Stearman

User Support
	Medha Bhagwat, Peter Cooper, Susan Dombrowski, Andrei Gabrielian
	Renata Geer, Scott McGinnis, Donna Messersmith, Rana Morris, Vyvy Pham,
	Monica Romiti, Eric Sayers, Tao Tao, David Wheeler 

Project Direction
	David Lipman


Acknowledgments - 

  Contractor support for GenBank production and distribution has been
provided by Management Systems Designers, Inc., ComputerCraft Corporation,
and The KEVRIC Company, Inc.

6.7 Disclaimer

  The United States Government makes no representations or warranties
regarding the content or accuracy of the information.  The United States
Government also makes no representations or warranties of merchantability
or fitness for a particular purpose or that the use of the sequences will
not infringe any patent, copyright, trademark, or other rights.  The
United States Government accepts no responsibility for any consequence
of the receipt or use of the information.

  For additional information about GenBank releases, please contact
NCBI by e-mail at info@ncbi.nlm.nih.gov, by phone at (301) 496-2475,
or by mail at:

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Support Center