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LTF lactotransferrin [ Equus caballus (horse) ]

Gene ID: 100033944, updated on 8-Mar-2024

Summary

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Official Symbol
LTFprovided by VGNC
Official Full Name
lactotransferrinprovided by VGNC
Primary source
VGNC:VGNC:56831
See related
Ensembl:ENSECAG00000021499
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
LF
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 16 NC_009159.3 (41879030..41907637)
102 previous assembly EquCab2.0 (GCF_000002305.2) 16 NC_009159.2 (40297513..40326126)

Chromosome 16 - NC_009159.3Genomic Context describing neighboring genes Neighboring gene cripto, EGF-CFC family member Neighboring gene leucine rich repeat containing 2 Neighboring gene receptor transporter protein 3 Neighboring gene C-C motif chemokine receptor like 2 Neighboring gene C-C chemokine receptor type 5 Neighboring gene C-C motif chemokine receptor 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lactoferrin expression and secretion in the stallion epididymis. Pearl CA, et al. Reprod Biol, 2014 Apr. PMID 24856474
  2. Lactoferrin, a glycoprotein with immunomodulatory and mast cell stabilising properties, in skin of horses suffering from Culicoides hypersensitivity. Kolm G, et al. Res Vet Sci, 2007 Oct. PMID 17222435
  3. Three-dimensional structure of mare diferric lactoferrin at 2.6 A resolution. Sharma AK, et al. J Mol Biol, 1999 Jun 4. PMID 10366507
  4. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in antibacterial humoral response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in recycling endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lactotransferrin
Names
lactoferrin
NP_001157446.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163974.1 → NP_001157446.1  lactotransferrin precursor

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000017
    UniProtKB/Swiss-Prot
    O77811
    UniProtKB/TrEMBL
    A0A3Q2HKG3
    Related
    ENSECAP00000033689.2, ENSECAT00000033748.3
    Conserved Domains (4) summary
    smart00094
    Location:364 → 692
    TR_FER; Transferrin
    cd13617
    Location:361 → 692
    PBP2_transferrin_C; The C-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    cd13618
    Location:24 → 351
    PBP2_transferrin_N; The N-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    pfam00405
    Location:25 → 352
    Transferrin; Transferrin

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009159.3 Reference EquCab3.0 Primary Assembly

    Range
    41879030..41907637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77811.1 GenPept UniProtKB/Swiss-Prot:O77811

Gene LinkOut

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