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CLU clusterin [ Equus caballus (horse) ]

Gene ID: 100034172, updated on 27-Jun-2020

Summary

Official Symbol
CLUprovided by VGNC
Official Full Name
clusterinprovided by VGNC
Primary source
VGNC:VGNC:16642
See related
Ensembl:ENSECAG00000007010
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Summary
This gene encodes a protein that is similar to the human clusterin protein, a secreted chaperone that can also be found in the cell cytosol under certain stress conditions. The human protein has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. [provided by RefSeq, May 2011]
Orthologs
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Genomic context

See CLU in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 2 NC_009145.3 (56547413..56562966, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 2 NC_009145.2 (56197758..56213307, complement)

Chromosome 2 - NC_009145.3Genomic Context describing neighboring genes Neighboring gene epoxide hydrolase 2 Neighboring gene L-gulonolactone oxidase Neighboring gene scavenger receptor class A member 3 Neighboring gene coiled-coil domain containing 25 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081944.1NP_001075413.1  clusterin precursor

    See identical proteins and their annotated locations for NP_001075413.1

    Status: PROVISIONAL

    Source sequence(s)
    L46797
    UniProtKB/Swiss-Prot
    Q29482
    Related
    ENSECAP00000005450.2, ENSECAT00000007460.3
    Conserved Domains (3) summary
    smart00030
    Location:22227
    CLb; CLUSTERIN Beta chain
    smart00035
    Location:228443
    CLa; CLUSTERIN alpha chain
    pfam01093
    Location:29445
    Clusterin; Clusterin

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009145.3 Reference EquCab3.0 Primary Assembly

    Range
    56547413..56562966 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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