LGALS3 galectin 3 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: LGALS3provided by VGNC
Official Full Name: galectin 3provided by VGNC
Primary source: VGNC:VGNC:89694
See related: Ensembl:ENSSSCG00000005055
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Biased expression in lung (RPKM 119.3), subcutaneous adipose (RPKM 57.4) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	1	NC_010443.5 (184478639..184496155)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	1	NC_010443.4 (204956478..204974108)

Chromosome 1 - NC_010443.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Altrenogest affects expression of galectin-3 and fibroblast growth factor 9 in the reproductive tract of sows.
Title: Altrenogest affects expression of galectin-3 and fibroblast growth factor 9 in the reproductive tract of sows.
Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12.
Title: Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12 in vitro.
these results suggest that galectin-3 is transiently expressed in follicular cells in the unilaminar ovarian follicles (primordial and primary) but not in multilaminar ovarian follicles (primary to tertiary), implying that galectin-3 is embryologically involved in ovum generation
Title: Unilaminar follicular cells transiently express galectin-3 during ovarian folliculogenesis in pigs.
galectin-3 plays a role in cell survival and cell adhesion in the epithelium of the porcine vomeronasal organ in all age groups.
Title: Galectin-3 immunohistochemistry in the vomeronasal organ of the domestic pig, Sus scrofa.
Galectin-3 is detected in the retinas of two-day-old pigs and that the expression in Muller cells increases with postnatal development.[galectin-3]
Title: Immunohistochemical localization of galectin-3 in the pig retina during postnatal development.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables IgE binding	IEA Inferred from Electronic Annotation more info	PubMed
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables laminin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in eosinophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in macrophage chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of extrinsic apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of calcium ion import	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in immunological synapse	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: galectin-3

Names: lectin galactoside-binding soluble 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.