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Ly6c2 lymphocyte antigen 6 complex, locus C2 [ Mus musculus (house mouse) ]

Gene ID: 100041546, updated on 5-Jan-2022

Summary

Official Symbol
Ly6c2provided by MGI
Official Full Name
lymphocyte antigen 6 complex, locus C2provided by MGI
Primary source
MGI:MGI:3712069
See related
Ensembl:ENSMUSG00000022584
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly-6C2; Ly-6C.2
Summary
Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Located in cell surface. Orthologous to human LY6H (lymphocyte antigen 6 family member H). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in spleen adult (RPKM 66.9), mammary gland adult (RPKM 63.7) and 21 other tissues See more
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Genomic context

See Ly6c2 in Genome Data Viewer
Location:
15; 15 D3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74980010..74983878, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75108161..75112066, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (74938591..74942379, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 complex, locus C1 Neighboring gene predicted gene 5960 Neighboring gene lymphocyte antigen 6 complex, locus A2 Neighboring gene lymphocyte antigen 6 complex, locus G

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Clone Names

  • MGC103163

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetylcholine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acetylcholine receptor inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in acetylcholine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
lymphocyte antigen 6C2
Names
lymphocyte antigen 6C precursor (Ly-6C)
lymphocyte differentiation antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099217.2NP_001092687.1  lymphocyte antigen 6C2 precursor

    See identical proteins and their annotated locations for NP_001092687.1

    Status: VALIDATED

    Source sequence(s)
    AC116498
    Consensus CDS
    CCDS49638.1
    UniProtKB/Swiss-Prot
    P0CW03
    Related
    ENSMUSP00000098110.4, ENSMUST00000100542.10
    Conserved Domains (1) summary
    pfam00021
    Location:29102
    UPAR_LY6; u-PAR/Ly-6 domain
  2. NM_001357693.1NP_001344622.1  lymphocyte antigen 6C2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC116498
    Consensus CDS
    CCDS49638.1
    Related
    ENSMUSP00000139556.2, ENSMUST00000191451.2
    Conserved Domains (1) summary
    pfam00021
    Location:29102
    UPAR_LY6; u-PAR/Ly-6 domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    74980010..74983878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245390.4XP_011243692.1  lymphocyte antigen 6C2 isoform X1

    See identical proteins and their annotated locations for XP_011243692.1

    UniProtKB/Swiss-Prot
    P0CW03
    Conserved Domains (1) summary
    pfam00021
    Location:29102
    UPAR_LY6; u-PAR/Ly-6 domain
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