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alv alveolin [ Oryzias latipes (Japanese medaka) ]

Gene ID: 100049214, updated on 9-Nov-2023

Summary

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Gene symbol
alv
Gene description
alveolin
See related
EnsemblRapid:ENSORLG00000020369
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryzias latipes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
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Genomic context

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Location:
chromosome: 24
Exon count:
10
Annotation release Status Assembly Chr Location
103 current ASM223467v1 (GCF_002234675.1) 24 NC_019882.2 (616664..618323, complement)
102 previous assembly ASM31367v1 (GCF_000313675.1) Unplaced Scaffold NW_004089794.1 (36829..38576)

Chromosome 24 - NC_019882.2Genomic Context describing neighboring genes Neighboring gene BTB (POZ) domain containing 9 Neighboring gene AN1-type zinc finger protein 3 Neighboring gene insulin-like growth factor 2 receptor Neighboring gene uncharacterized LOC111947057 Neighboring gene solute carrier family 22 member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An oocyte-specific astacin family protease, alveolin, is released from cortical granules to trigger egg envelope hardening during fertilization in medaka (Oryzias latipes). Shibata Y, et al. Dev Biol, 2012 Dec 15. PMID 23022660
  2. Identification and cDNA cloning of alveolin, an extracellular metalloproteinase, which induces chorion hardening of medaka (Oryzias latipes) eggs upon fertilization. Shibata Y, et al. J Biol Chem, 2000 Mar 24. PMID 10722665
  3. Systematic identification of genes expressed during early oogenesis in medaka. Kanamori A. Mol Reprod Dev, 2000 Jan. PMID 10602271
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. alveolin transcript was detected only in ovarian preparations, confirming the specific expression of alveolin in the ovary
    Title: An oocyte-specific astacin family protease, alveolin, is released from cortical granules to trigger egg envelope hardening during fertilization in medaka (Oryzias latipes).
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alveolin
Names
choriolysin L-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104669.1 → NP_001098139.1  alveolin precursor

    See identical proteins and their annotated locations for NP_001098139.1

    Status: PROVISIONAL

    Source sequence(s)
    AB030957
    UniProtKB/TrEMBL
    A0A3P9IQA9, H2N1E5, Q9IBE7
    Related
    ENSORLP00000025247.3, ENSORLT00000025248.3
    Conserved Domains (2) summary
    cd04280
    Location:88 → 259
    ZnMc_astacin_like; Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to ...
    pfam01400
    Location:84 → 263
    Astacin; Astacin (Peptidase family M12A)

RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM223467v1 Primary Assembly

Genomic

  1. NC_019882.2 Reference ASM223467v1 Primary Assembly

    Range
    616664..618323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023952690.1 → XP_023808458.1  alveolin isoform X2

    UniProtKB/TrEMBL
    A0A3B3INV8, A0A3P9IQA9
    Conserved Domains (1) summary
    cd04280
    Location:77 → 248
    ZnMc_astacin_like; Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to ...

  2. XM_011493153.3 → XP_011491455.1  alveolin isoform X1

    UniProtKB/TrEMBL
    A0A3P9IQA9
    Conserved Domains (2) summary
    cd04280
    Location:90 → 261
    ZnMc_astacin_like; Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to ...
    pfam01400
    Location:86 → 265
    Astacin; Astacin (Peptidase family M12A)
Nucleotide Protein
Heading Accession and Version

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