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PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [ Equus caballus (horse) ]

Gene ID: 100064130, updated on 8-Mar-2024

Summary

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Official Symbol
PIK3C2Gprovided by VGNC
Official Full Name
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gammaprovided by VGNC
Primary source
VGNC:VGNC:21444
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See PIK3C2G in Genome Data Viewer
Location:
chromosome: 6
Exon count:
35
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (46341187..46683355)
102 previous assembly EquCab2.0 (GCF_000002305.2) 6 NC_009149.2 (45205716..45546327)

Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111773801 Neighboring gene RERG like Neighboring gene serine/threonine-protein phosphatase PGAM5, mitochondrial pseudogene Neighboring gene 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like Neighboring gene F-actin-capping protein subunit alpha-3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
Names
phosphoinositide-3-kinase, class 2, gamma polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009149.3 Reference EquCab3.0 Primary Assembly

    Range
    46341187..46683355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023643190.1 → XP_023498958.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1

    Conserved Domains (6) summary
    cd04012
    Location:540 → 695
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:712 → 880
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:279 → 367
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:1268 → 1368
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl14603
    Location:1390 → 1502
    C2; C2 domain
    cl21453
    Location:887 → 1239
    PKc_like; Protein Kinases, catalytic domain

  2. XM_023643189.1 → XP_023498957.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1

    Conserved Domains (6) summary
    cd04012
    Location:540 → 695
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:712 → 880
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:279 → 367
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:1268 → 1368
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl14603
    Location:1390 → 1502
    C2; C2 domain
    cl21453
    Location:887 → 1239
    PKc_like; Protein Kinases, catalytic domain

  3. XM_023643191.1 → XP_023498959.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X2

    Conserved Domains (6) summary
    cd04012
    Location:520 → 675
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:692 → 860
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:279 → 367
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:1248 → 1348
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl14603
    Location:1370 → 1482
    C2; C2 domain
    cl21453
    Location:867 → 1219
    PKc_like; Protein Kinases, catalytic domain

  4. XM_023643192.1 → XP_023498960.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X3

    Conserved Domains (6) summary
    cd04012
    Location:479 → 634
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cl00271
    Location:651 → 819
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:279 → 367
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl02563
    Location:1207 → 1307
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl14603
    Location:1329 → 1441
    C2; C2 domain
    cl21453
    Location:826 → 1178
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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