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CTTNBP2 cortactin binding protein 2 [ Ovis aries (sheep) ]

Gene ID: 100126575, updated on 8-Mar-2024

Summary

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Gene symbol
CTTNBP2
Gene description
cortactin binding protein 2
See related
EnsemblRapid:ENSOARG00020016233
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
CORTBP2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 4 NC_056057.1 (51988687..52161248)

Chromosome 4 - NC_056057.1Genomic Context describing neighboring genes Neighboring gene T-cell receptor gamma chain C region C10.5-like Neighboring gene actin-related protein 2/3 complex subunit 1A-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC121819401 Neighboring gene CF transmembrane conductance regulator Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056057.1 Chromosome 4 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cortactin-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195311.1 → NP_001182240.1  cortactin-binding protein 2

    See identical proteins and their annotated locations for NP_001182240.1

    Status: PROVISIONAL

    Source sequence(s)
    DP000179
    UniProtKB/Swiss-Prot
    Q09YI1
    UniProtKB/TrEMBL
    A0A836D2C4
    Related
    ENSOARP00020020695.2, ENSOART00020024931.2
    Conserved Domains (9) summary
    PRK11331
    Location:1070 → 1359
    PRK11331; 5-methylcytosine-specific restriction enzyme subunit McrB; Provisional
    cd00204
    Location:731 → 856
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam09727
    Location:36 → 180
    CortBP2; Cortactin-binding protein-2
    pfam12718
    Location:124 → 245
    Tropomyosin_1; Tropomyosin like
    pfam12796
    Location:741 → 832
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:705 → 757
    Ank_4; Ankyrin repeats (many copies)
    pfam13863
    Location:187 → 271
    DUF4200; Domain of unknown function (DUF4200)
    sd00045
    Location:769 → 800
    ANK; ANK repeat [structural motif]
    cl09111
    Location:123 → 246
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056057.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    51988687..52161248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042248274.2 → XP_042104208.1  cortactin-binding protein 2 isoform X2

    Conserved Domains (4) summary
    PRK11331
    Location:378 → 667
    PRK11331; 5-methylcytosine-specific restriction enzyme subunit McrB; Provisional
    COG0666
    Location:13 → 134
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:77 → 108
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:113 → 163
    Ank_4; Ankyrin repeats (many copies)

  2. XM_060414347.1 → XP_060270330.1  cortactin-binding protein 2 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09YI1.1 GenPept UniProtKB/Swiss-Prot:Q09YI1

Gene LinkOut

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